Results 271 to 280 of about 125,197 (343)

The MdERF17–MdbHLH149 Module Mediates Ethylene‐Induced Starch Degradation Through the Transcriptional Repression of α‐Amylase MdAMY1 in Apple

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3141-3157, May 2026.
ABSTRACT The ripening of climacteric fruits is characterised by a sharp increase in ethylene production, coinciding with the conversion of starch into soluble sugars. However, the regulatory interplay between ethylene and starch degradation in apple remains largely unclear. Here, we report a negative correlation between starch accumulation and ethylene
Fan Xiao, Chu‐Kun Wang, Jiu‐Cheng Zhang, Xin‐Yue Jian, Ying Xiang, Wang‐Jiang Zhang, Jin‐Chao Meng, Wen‐Yan Wang, Da‐Gang Hu   +8 more
wiley   +1 more source

Targeting FANCM using the antisense oligonucleotides to treat the ALT-positive cancers. [PDF]

Mol Ther Nucleic Acids
Naji S, Tong C, Ragupathi A, Xiao M, Zhang D.   +4 more
europepmc   +1 more source

Inhibition of calreticulin by protein nanoparticles carrying antisense oligonucleotides reduce gene expression and infection of <i>Trypanosoma cruzi</i> trypomastigotes on mammalian cells. [PDF]

Nanomedicine (Lond)
Prestegui-Martel B, Martínez I, Cárdenas-Guerra RE, Cortés-Coss AK, Del Toro-Ríos X, Hernández-Garcia A, Espinoza B.   +6 more
europepmc   +1 more source

Unraveling and controlling late-onset neurotoxicity of antisense oligonucleotides through strategic chemical modifications. [PDF]

Mol Ther Nucleic Acids
Kuroda T, Yoshioka K, Mon SSL, Katsuyama M, Sato K, Isogai E, Yoshida-Tanaka K, Iwata-Hara R, Yamaguchi T, Obika S, Yokota T.   +10 more
europepmc   +1 more source

The Regulation and Function of Hippo/YAP Pathway in Cancer

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Hippo/YAP pathway signaling plays critical roles in the progression of multiple cancer types. This review summarizes current knowledge of Hippo/YAP pathway regulation and function in cancer. We discuss the core components of the Hippo/YAP pathway; its crosstalk with other signaling pathways; regulation by non‐coding RNAs; roles of YAP signaling in ...
Chinmoy Ghosh, Ruchi Kakar, Seline Torkamboor, Yue Sun   +3 more
wiley   +1 more source

Identifying antisense oligonucleotides for targeted inhibition of insulin receptor isoform A. [PDF]

Front Oncol
Galifi CA, Dikdan RJ, Kantak D, Bulatowicz JJ, Maingrette K, Gunderson SI, Wood TL.   +6 more
europepmc   +1 more source

Synthesis of 4'-C-α-Aminoethoxy-2'-O-Methyl-5-Methyl- and 5-Propynyl-Uridine Phosphoramidites for Structurally Optimized Antisense Oligonucleotides. [PDF]

Curr Protoc
Mahmoud EM, Ueno Y.
europepmc   +1 more source

Cycloalkane Incorporation Into the 2',4'-Bridge of Locked Nucleic Acid: Enhancing Nuclease Stability, Reducing Phosphorothioate Modifications, and Lowering Hepatotoxicity in Antisense Oligonucleotides. [PDF]

JACS Au
Yamaguchi T, Komine H, Sugiura T, Kumagai R, Yoshida T, Sasaki K, Nakayama T, Kamada H, Inoue T, Obika S.   +9 more
europepmc   +1 more source

Antisense oligonucleotide-mediated exon skipping strategies as the treatment for rare diseases

, 2020
Dunhui Li
openalex   +1 more source

Targeting FANCM by antisense oligonucleotides in ALT-positive cancers. [PDF]

Mol Ther Nucleic Acids
Tieo G, Bao Ying Lim N, Lim KW, Dröge P, Phan AT, Jeitany M.   +5 more
europepmc   +1 more source