Results 81 to 90 of about 2,848 (185)

Multi‐Frame Image Registration for Automated Ventricular Function Assessment in Single Breath‐Hold Cine MRI Using Limited Labels

Magnetic Resonance in Medicine, Volume 95, Issue 3, Page 1762-1777, March 2026.
ABSTRACT Purpose This study aims to develop an automated framework for operator‐independent assessment of cardiac ventricular function from highly accelerated images. Methods We introduce a deep learning framework that generates reliable ventricular volumetric parameters and strain measures from fully sampled and retrospectively accelerated MR images ...
Aya Ghoul, Paxstan Cassal Paulson, Andreas Lingg, Patrick Krumm, Kerstin Hammernik, Daniel Rueckert, Sergios Gatidis, Thomas Küstner   +7 more
wiley   +1 more source

Antisynthetase syndrome in pregnancy: a case report and review of the literature

, 2021
Aim: Antisynthetase syndrome (anti-SS) is a rare systemic autoimmune disease characterised by autoantibodies against aminoacyl-tRNA synthetases manifesting as one or more components of the classic triad: interstitial lung disease (ILD), arthritis and ...
Chakradeo, Katrina, Wolski, Penny, Hennessey, Ashleigh, Kowitz, Monique   +3 more
core   +1 more source

Use of anti-B-cell therapy in case of antisynthetase syndrome as the severest subtype of polymyositis/dermatomyositis

Терапевтический архив, 2014
Antisynthetase syndrome encompassing a symptom complex with severe interstitial lung disease is the severest subtype of polymyositis and dermatomyositis.
O A Antelava, A N Khelkovskaia-Sergeeva, G M Tarasova, N Iu Nikishina, N E Lopatina, S G Pal'shina, T P Fedina, E G Sazhina   +7 more
doaj  

A Case of Anti-Jo-1 Myositis with Unique Biopsy Findings

Case Reports in Rheumatology, 2022
Antisynthetase syndrome (ASS) or anti-Jo-1 antibody syndrome has a classic clinical presentation including arthritis, myositis, interstitial lung disease, mechanic hands, and/or Raynaud’s phenomenon.
Beenish Zulfiqar, Pavel Aksionav, Mohamad Bittar, Cathy Chapman   +3 more
doaj   +1 more source

ABNORMAL NAILFOLD VIDEOCAPILLAROSCOPY IN PATIENTS WITH ANTISYNTHETASE SYNDROME: CASE REPORTS AND REVIEW OF THE LITERATURE [PDF]

Romanian Journal of Rheumatology, 2017
Classified as a distinct subset of idiopathic inflammatory myopathies, anti-synthetase syndrome is an orphan autoimmune disease characterized by the presence of anti-aminoacyl-tRNA synthetase antibodies associated with a spectrum of clinical features ...
Cristina Pomirleanu, Georgiana Strugariu, Iulian Resmerita, Andreea Axinte, Codrina Ancuta   +4 more
doaj   +1 more source

Clinical Characteristics and Evolution of Interstitial Lung Disease in Subtypes of Idiopathic Inflammatory Myositis With Prevalent Lung Manifestation: A Retrospective Analysis

ACR Open Rheumatology, Volume 8, Issue 2, February 2026.
Objective Interstitial lung disease (ILD) is common in idiopathic inflammatory myositis (IIM), particularly in antisynthetase syndrome (ASyS), antimelanoma differentiation‐associated protein 5 (anti‐MDA5) syndrome, and scleromyositis. ILD can progress despite resolution of extrapulmonary symptoms, termed postmyopathic progressive pulmonary fibrosis ...
Julia Clark, Dora Chan, Damon Dhillon, Jan Dutz, Gillian Goobie, Kun Huang   +5 more
wiley   +1 more source

EGFR‐mutant lung adenocarcinoma associated with antisynthetase syndrome successfully treated with osimertinib

Thoracic Cancer, 2021
Here, we report a rare case involving a 66‐year‐old man with epidermal growth factor receptor (EGFR)‐mutant lung adenocarcinoma and antisynthetase syndrome (ASS) treated with osimertinib.
Reina Hara, Masaki Kanazu, Ami Iwai, Tomoki Kuge, Mikako Ishijima, Takeshi Uenami, Yuki Akazawa, Yukihiro Yano, Toshihiko Yamaguchi, Masahide Mori   +9 more
doaj   +1 more source

Anti-PL-7 antisynthetase syndrome with onset of diffuse interstitial lung disease and myopathy: a case report [PDF]

Beyond Rheumatology
Introduction: Antisynthetase syndrome (ASyS) is a rare autoimmune disorder belonging to the spectrum of idiopathic inflammatory myopathies, with an estimated incidence of 0.56 cases per 100,000 person-years and a prevalence of 9.21 per 100,000 ...
K. Burbano, M. Benavides, J. Zambrano
doaj   +1 more source

Steroid‐Refractory Cryptogenic Organising Pneumonia (COP) in a Patient With Mannose‐Binding Lectin (MBL) Deficiency

Respirology Case Reports, Volume 14, Issue 2, February 2026.
A 67‐year‐old man with cryptogenic organising pneumonia developed recurrent relapses despite corticosteroid and mycophenolate therapy. A complete absence of mannose‐binding lectin was identified, suggesting impaired apoptotic cell clearance as a contributor to persistent inflammation.
Ilias E. Dimeas, Sotirios I. Sinis, Paraskevi Kirgou, Cormac McCarthy, Zoe Daniil   +4 more
wiley   +1 more source

Alu Overexpression Leads to an Increased Double‐Stranded RNA Signature in Dermatomyositis

Arthritis &Rheumatology, Volume 78, Issue 1, Page 209-222, January 2026.
Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the noncoding genome in disease pathogenesis.
Rayan Najjar, Andrew Mammen, Tomas Mustelin   +2 more
wiley   +1 more source