Results 61 to 70 of about 2,848 (185)

A Review of Antisynthetase Syndrome-Associated Interstitial Lung Disease [PDF]

International Journal of Molecular Sciences
P Patel, Aamir Ajmeri
exaly   +2 more sources

Influence of MUC5B gene on antisynthetase syndrome [PDF]

Scientific Reports, 2020
AbstractMUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity pneumonitis (CHP). Due to this, we evaluated the implication of MUC5B rs35705950 in antisynthetase syndrome (ASSD), a pathology ...
Raquel López-Mejías, Sara Remuzgo-Martínez, Fernanda Genre, Verónica Pulito-Cueto, Sonia M. Fernández Rozas, Javier Llorca, David Iturbe Fernández, Víctor M. Mora Cuesta, Norberto Ortego-Centeno, Nair Pérez Gómez, Antonio Mera-Varela, Julia Martínez-Barrio, Francisco Javier López-Longo, Verónica Mijares, Leticia Lera-Gómez, María Piedad Usetti, Rosalía Laporta, Virginia Pérez, Alicia De Pablo Gafas, María Aránzazu Alfranca González, Jaime Calvo-Alén, Fredeswinda Romero-Bueno, Olga Sanchez-Pernaute, Laura Nuno, Gema Bonilla, Alejandro Balsa, Fernanda Hernández-González, Ignacio Grafia, Sergio Prieto-González, Javier Narvaez, Ernesto Trallero-Araguas, Albert Selva-O’Callaghan, Oreste Gualillo, Santos Castañeda, Lorenzo Cavagna, José M. Cifrian, Miguel A. González-Gay   +36 more
openaire   +11 more sources

Development of myasthenia gravis 8 years after interstitial lung disease associated with antisynthetase (anti‐EJ antibody) syndrome

Clinical Case Reports, 2017
Key Clinical Message Patients with antisynthetase‐positive interstitial lung disease (ILD) alone sometimes develop myositis during follow‐up, but myasthenia gravis (MG) overlapping on antisynthetase syndrome is unusual.
Takashi Ishiguro, Naho Kagiyama, Eriko Kawate, Kyuto Odashima, Yotaro Takaku, Kazuyoshi Kurashima, Noboru Takayanagi   +6 more
doaj   +1 more source

Early predominant inflammatory myopathy in anti‐glycyl‐tRNA synthetase (EJ) antibody positive antisynthetase syndrome

Clinical Case Reports, 2021
It is important to consider antisynthetase syndrome in the differential diagnosis of patients presenting with weakness, respiratory distress, and a constellation of complaints spanning multiple organ systems, as this will change clinical management.
Robin Warner, Derrece Reid
doaj   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Improved Detection of Myositis‐Specific Autoantibodies Using Luciferase Immunoprecipitation Systems Assay: Comparison With Line Blot and Conventional Immunoprecipitation

Arthritis &Rheumatology, EarlyView.
Objective Myositis‐specific autoantibodies guide the diagnosis and classification of idiopathic inflammatory myopathies, but current immunoassays vary in accuracy, particularly for autoantibodies associated with interstitial lung disease. To compare the performance of the luciferase immunoprecipitation systems (LIPS) assay with line blot and ...
Peter D. Burbelo, Iago Pinal‐Fernandez, Maria Casal‐Dominguez, Xin Tian, Shijinqiu Gao, Neha Gupta, Eric W. Robbins, John A. Chiorini, Christopher A. Mecoli, Lisa Christopher‐Stine, Livia Casciola‐Rosen, Andrew L. Mammen, Sonye K. Danoff, Anthony F. Suffredini, Julio A. Huapaya   +14 more
wiley   +1 more source

Antisynthetase syndrome presenting as interstitial lung disease: a case report

Journal of Medical Case Reports, 2019
Background Antisynthetase syndrome is a relatively uncommon entity, and can be easily missed if not specifically looked for in adults whose initial presentation is with interstitial lung disease. Its presentation with interstitial lung disease alters its
Aliena Badshah, Iqbal Haider, Shayan Pervez, Mohammad Humayun   +3 more
doaj   +1 more source

New Onset of Dermatomyositis/Polymyositis during Anti-TNF-α Therapies: A Systematic Literature Review

The Scientific World Journal, 2014
We performed a systematic search of databases from 1990 to 2013 to identify articles concerning the new onset of dermatomyositis/polymyositis (DM/PM) in patients treated with anti-TNF-α therapy.
Alexandra Maria Giovanna Brunasso, Werner Aberer, Cesare Massone   +2 more
doaj   +1 more source

Chimeric Antigen Receptor T‐Cells in Myasthenia Gravis: Advances, Safety Challenges, and Future Directions

Muscle &Nerve, Volume 73, Issue 6, Page 942-951, June 2026.
ABSTRACT This review examines the emerging application of chimeric antigen receptor (CAR) T‐cell therapy in myasthenia gravis (MG), with emphasis on safety, efficacy signals, and future therapeutic potential in treatment‐refractory disease. A comprehensive literature search was conducted across PubMed, medRxiv, bioRxiv, and Google Scholar for studies ...
Tobias Hegelmaier, Alexander Duscha, Christiane Desel, Sarah Stassen, Tim Krzemien, Ann‐Katrin Hennemann, Vaia Pappa, Aiden Haghikia   +7 more
wiley   +1 more source

[Acute interstitial lung disease revealing antisynthetase syndrome].

, 2011
International audienceINTRODUCTION: The antisynthetase syndrome is characterized by the presence of myositis, interstitial lung disease, arthritis, Raynaud's phenomenon, mechanics hands and anti-Jo1 antibody (histidyl tRNA synthetase).
Bizien, Nicolas, N. Bizien, J.-M. Boles, Renault, Anne, A. Delluc, Boles, Jean-Michel, Delluc, Aurélien, A. Renault   +7 more
core   +1 more source