Results 51 to 60 of about 2,848 (185)

Drug-induced antisynthetase syndrome [PDF]

Postgraduate Medical Journal, 1997
Summary We present a case of antisynthetase syndrome whose predominant feature was fibrosing alveolitis and which may have been drug-induced. This responded well to steroids and cyclophosphamide.
D R, Thickett, A B, Millar
openaire   +2 more sources

Coronary artery dilation associated with anti-synthetase syndrome in an adolescent

Pediatric Rheumatology Online Journal, 2019
Background Idiopathic inflammatory myopathies (IIM) are a group of systemic autoimmune disorders primarily affecting skeletal muscle. Pediatric coronary artery dilation is frequently discussed in Kawasaki disease.
Karim Asi, Anand Gourishankar, Ankur Kamdar   +2 more
doaj   +1 more source

Clinical utility of anti‐cytosolic 5’‐nucleotidase 1A antibody in idiopathic inflammatory myopathies

Annals of Clinical and Translational Neurology, 2021
Objective To define the clinicopathologic features and diagnostic utility associated with anti‐cytosolic 5′‐nucleotidase 1A (NT5C1A) antibody seropositivity in idiopathic inflammatory myopathies (IIMs).
Chiseko Ikenaga, Andrew R. Findlay, Namita A. Goyal, Sarah Robinson, Jonathan Cauchi, Yessar Hussain, Leo H. Wang, Joshua C. Kershen, Brent A. Beson, Michael Wallendorf, Robert C. Bucelli, Tahseen Mozaffar, Alan Pestronk, Conrad C. Weihl   +13 more
doaj   +1 more source

The Diagnosis and Treatment of Antisynthetase Syndrome [PDF]

Clinical Pulmonary Medicine, 2016
Anti-synthetase syndrome is an autoimmune condition, characterized by antibodies directed against an aminoacycl transfer RNA synthetase along with clinical features that can include interstitial lung disease, myositis, Raynaud's phenomenon, and arthritis.
Leah J, Witt, James J, Curran, Mary E, Strek   +2 more
openaire   +2 more sources

Overlapping rheumatoid arthritis and antisynthetase syndrome with secondary Sjögren’s syndrome: a case report and review of the literature

Journal of Medical Case Reports, 2022
Background Overlap syndromes account for about 25% of autoimmune diseases. They are many possible combinations of known autoimmune diseases increasingly diagnosed with the identification of of a large number of autoantibodies.
W. S. Weerasinghe, Chandrika Jayasinghe
doaj   +1 more source

Anti‐synthetase syndrome associated interstitial lung disease after combination dual immune checkpoint inhibition

Respirology Case Reports, 2023
Immune checkpoint inhibitors (ICIs) unleash potent anti‐tumour responses but with frequent off‐target immune‐mediated adverse events (irAE). ICIs can induce a spectrum of rheumatologic manifestations including inflammatory arthritis, Sjögren's syndrome ...
Peter T. Bell, Thomas Beaton, Matthew Terrill, David Gillis, John Goddard   +4 more
doaj   +1 more source

A Case of Anti-Synthetase Syndrome Successfully Treated with Mycophenolate Mofetil and Rituximab but No Corticosteroids

European Journal of Case Reports in Internal Medicine, 2022
A patient with antisynthetase syndrome with pulmonary and muscular involvement was treated with immunosuppressive agents without corticosteroids. Rituximab was added to mycophenolate mofetil therapy with improvement in lung functional and imaging ...
Agnieszka Ewa Sieradzka, Bruno Naccini, Massimiliano Fontana   +2 more
doaj   +1 more source

ANTISITETASE SYNDROME: SERIES OF CASES DIAGNOSED IN A COMARCAL HOSPITAL

Galicia Clínica
Introduction: The antisynthetase syndrome is a rare autoimmune disease that affects multiple organs. It typically presents with polymyositis, interstitial lung disease, and antisynthetase autoantibodies.
Ignacio Lasierra Lavilla, Julien Paola Caballero Castro, Mario Nicolás Albani Pérez, Juan Salas Jarque, Lidia Estopiñan Fortea, Ignacio Vallés Tormo   +5 more
doaj   +1 more source

Antisynthetase Syndrome Masquerading as Hypersensitivity Pneumonitis

Respiration, 2021
Interstitial lung diseases (ILDs) cover a wide heterogeneous group of disorders, both of unknown and known causes. Accurate diagnosis is essential but, at the same time, presents many challenges. Typically, the distinction between idiopathic pulmonary fibrosis and fibrotic hypersensitivity pneumonitis (HP) can prove extremely difficult.
Tzilas, Vasilios, Sfikakis, Petros P., Bouros, Demosthenes   +2 more
openaire   +3 more sources

Acute respiratory distress syndrome secondary to antisynthetase syndrome is reversible with tacrolimus

, 2008
Polymyositis and interstitial lung diseases, predominantly nonspecific interstitial pneumonia (NSIP), are known to be frequent in antisynthetase syndrome, where anti-aminoacyl-tRNA synthetase antibodies are often identified.
Merz, T M, Suter, C, Nicod, L P, Gugger, M, Guglielmi, S   +4 more
core   +1 more source