Results 51 to 60 of about 2,373 (163)

New Onset of Dermatomyositis/Polymyositis during Anti-TNF-α Therapies: A Systematic Literature Review

open access: yesThe Scientific World Journal, 2014
We performed a systematic search of databases from 1990 to 2013 to identify articles concerning the new onset of dermatomyositis/polymyositis (DM/PM) in patients treated with anti-TNF-α therapy.
Alexandra Maria Giovanna Brunasso   +2 more
doaj   +1 more source

Outcomes of Immune Check Point Inhibitor Use in US Veterans With Pre‐Existing Idiopathic Inflammatory Myopathies: Case Series and Literature Review

open access: yesACR Open Rheumatology, Volume 8, Issue 8, August 2026.
Objective Our objective was to identify and describe the clinical characteristics and outcomes in patients with pre‐existing idiopathic inflammatory myopathies (IIMs) in the Veterans Health Administration (VHA) treated with immune checkpoint inhibitors (ICIs). Methods All veterans receiving ICI infusions were identified.
Denis Krutko   +8 more
wiley   +1 more source

Comparison of Rule‐Based Algorithms to Identify Patients With Idiopathic Inflammatory Myopathies in Electronic Health Records

open access: yesACR Open Rheumatology, Volume 8, Issue 7, July 2026.
Objective Studying rare diseases requires assembling robust, correctly classified cohorts. We compared the performance of seven published International Classification of Diseases, Ninth Revision (ICD‐9) and International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD‐10) code rule‐based algorithms in the ...
Ana Lucia Valle   +7 more
wiley   +1 more source

Antisynthetase Syndrome Associated with Sarcoidosis

open access: yesInternal Medicine, 2006
A 30-year-old man complained of polyarthralgia and fatigue. The clinical findings and laboratory data included myositis, polyarthritis, interstitial pneumonia, Raynaud's phenomenon, mechanic's hand, and anti PL-7 antibody (threonyl-tRNA synthetase antibody). All of these signs were consistent with antisynthetase syndrome.
Asanuma, Yu   +6 more
openaire   +3 more sources

IVIG for refractory dysphagia in Antisynthetase syndrome: A truth hard to swallow

open access: yesClinical Case Reports, 2022
Refractory dysphasia could be the main symptom of Antisynthetase syndrome (ASS). IVIG may have a major impact in the successful treatment of dysphasia in patients with ASS.
Mais Alnoukari   +6 more
doaj   +1 more source

Case of late diagnosis of dermatomyositis with anti-synthetic syndrome

open access: yesЛечащий Врач, 2021
Polymyositis (PM) and dermatomyositis (DM) are autoimmune diseases of skeletal muscles of unknown etiology, which belong to systemic diseases of the connective tissue and are collectively called «idiopathic inflammatory myopathies».
L. A. Smirnova   +2 more
doaj   +1 more source

Diffuse Alveolar Hemorrhage in a Patient with Antisynthetase Syndrome

open access: yesCase Reports in Rheumatology, 2019
An alveolar hemorrhage case is reported as the initial manifestation of antisynthetase syndrome in a 40-year-old man, who is admitted to the Emergency Department for diagnostic approach of chronic cough and progressive dyspnea.
D. A. Vargas-Gutiérrez   +7 more
doaj   +1 more source

Chimeric Antigen Receptor T‐Cells in Myasthenia Gravis: Advances, Safety Challenges, and Future Directions

open access: yesMuscle &Nerve, Volume 73, Issue 6, Page 942-951, June 2026.
ABSTRACT This review examines the emerging application of chimeric antigen receptor (CAR) T‐cell therapy in myasthenia gravis (MG), with emphasis on safety, efficacy signals, and future therapeutic potential in treatment‐refractory disease. A comprehensive literature search was conducted across PubMed, medRxiv, bioRxiv, and Google Scholar for studies ...
Tobias Hegelmaier   +7 more
wiley   +1 more source

Genetic Susceptibility to Antisynthetase Syndrome Associated With Single-Nucleotide Variants in the IL1B Gene That Lead Variation in IL-1β Serum Levels

open access: yesFrontiers in Medicine, 2020
The antisynthetase syndrome (ASSD) is an autoimmune disorder characterized by myositis, arthritis, mechanic's hands, fever, Raynaud phenomenon, and interstitial lung disease (ILD).
Marco Antonio Ponce-Gallegos   +10 more
doaj   +1 more source

Etiopathogenesis of Immune‐Mediated Necrotizing Myopathy: A Comprehensive Review of Recent Advances

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
This review systematically clarifies that the core of IMNM begins with specific autoantibodies, which in turn trigger complement activation, immune cell infiltration, and a storm of inflammatory factors. Together, these processes induce regulatory cell death and mitochondrial dysfunction, ultimately leading to muscle fiber necrosis. Genetic factors and
Chang Gao   +4 more
wiley   +1 more source

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