Results 71 to 80 of about 1,527,893 (148)

ABNORMAL NAILFOLD VIDEOCAPILLAROSCOPY IN PATIENTS WITH ANTISYNTHETASE SYNDROME: CASE REPORTS AND REVIEW OF THE LITERATURE [PDF]

Romanian Journal of Rheumatology, 2017
Classified as a distinct subset of idiopathic inflammatory myopathies, anti-synthetase syndrome is an orphan autoimmune disease characterized by the presence of anti-aminoacyl-tRNA synthetase antibodies associated with a spectrum of clinical features ...
Cristina Pomirleanu, Georgiana Strugariu, Iulian Resmerita, Andreea Axinte, Codrina Ancuta   +4 more
doaj   +1 more source

Outcomes of Immune Check Point Inhibitor Use in US Veterans With Pre‐Existing Idiopathic Inflammatory Myopathies: Case Series and Literature Review

ACR Open Rheumatology, Volume 8, Issue 8, August 2026.
Objective Our objective was to identify and describe the clinical characteristics and outcomes in patients with pre‐existing idiopathic inflammatory myopathies (IIMs) in the Veterans Health Administration (VHA) treated with immune checkpoint inhibitors (ICIs). Methods All veterans receiving ICI infusions were identified.
Denis Krutko, Selene Rubino, Gary A. Kunkel, Jessica A. Walsh, Jorge Rojas, Brian C. Sauer, Shardool Patel, Grant W. Cannon, Tawnie J. Braaten   +8 more
wiley   +1 more source

Efficacy and safety of telitacicept in patients with progressive interstitial lung disease associated with antisynthetase syndrome, rheumatoid arthritis, or Sjögren’s syndrome: a prospective observational study

Respiratory Research
Background Interstitial lung disease (ILD) is a severe complication of antisynthetase syndrome, rheumatoid arthritis, and Sjögren’s syndrome, contributing significantly to patient mortality. Standard treatment options remain limited. This study evaluated
Xue Chen, MingFang Sun, Ying Zhou, Fei Xiao, MengShan Li, YanLong Yang, HuanZi Dai   +6 more
doaj   +1 more source

EGFR‐mutant lung adenocarcinoma associated with antisynthetase syndrome successfully treated with osimertinib

Thoracic Cancer, 2021
Here, we report a rare case involving a 66‐year‐old man with epidermal growth factor receptor (EGFR)‐mutant lung adenocarcinoma and antisynthetase syndrome (ASS) treated with osimertinib.
Reina Hara, Masaki Kanazu, Ami Iwai, Tomoki Kuge, Mikako Ishijima, Takeshi Uenami, Yuki Akazawa, Yukihiro Yano, Toshihiko Yamaguchi, Masahide Mori   +9 more
doaj   +1 more source

Comparison of Rule‐Based Algorithms to Identify Patients With Idiopathic Inflammatory Myopathies in Electronic Health Records

ACR Open Rheumatology, Volume 8, Issue 7, July 2026.
Objective Studying rare diseases requires assembling robust, correctly classified cohorts. We compared the performance of seven published International Classification of Diseases, Ninth Revision (ICD‐9) and International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD‐10) code rule‐based algorithms in the ...
Ana Lucia Valle, Amy Vo, Rochelle L. Castillo, Yumeko Kawano, Leah M. Santacroce, Daniel H. Solomon, Katherine P. Liao, Candace H. Feldman   +7 more
wiley   +1 more source

Anti-PL-7 antisynthetase syndrome with onset of diffuse interstitial lung disease and myopathy: a case report [PDF]

Beyond Rheumatology
Introduction: Antisynthetase syndrome (ASyS) is a rare autoimmune disorder belonging to the spectrum of idiopathic inflammatory myopathies, with an estimated incidence of 0.56 cases per 100,000 person-years and a prevalence of 9.21 per 100,000 ...
K. Burbano, M. Benavides, J. Zambrano
doaj   +1 more source

T‐cell engagers in autoimmune rheumatic diseases: From concept to clinical practice

Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.
Christina Düsing, Andrea‐Hermina Györfi, Jörg H. W. Distler   +2 more
wiley   +1 more source

An Exploratory Analysis of Antibody Dynamics in Isolated Organ Involvement of Antisynthetase Syndrome: A Single‐Center Experience

ACR Open Rheumatology, Volume 8, Issue 6, June 2026.
Objective To characterize longitudinal anti–aminoacyl–tRNA synthetase (anti‐ARS) antibody kinetics in antisynthetase syndrome (ASyS) with isolated organ involvement (IOI) and examine associations with clinical trajectories versus multiple organ involvement (MOI).
Takeshi Suzuki, Misa Yamaji, Hiroaki Harada, Kimito Kawahata   +3 more
wiley   +1 more source

Chimeric Antigen Receptor T‐Cells in Myasthenia Gravis: Advances, Safety Challenges, and Future Directions

Muscle &Nerve, Volume 73, Issue 6, Page 942-951, June 2026.
ABSTRACT This review examines the emerging application of chimeric antigen receptor (CAR) T‐cell therapy in myasthenia gravis (MG), with emphasis on safety, efficacy signals, and future therapeutic potential in treatment‐refractory disease. A comprehensive literature search was conducted across PubMed, medRxiv, bioRxiv, and Google Scholar for studies ...
Tobias Hegelmaier, Alexander Duscha, Christiane Desel, Sarah Stassen, Tim Krzemien, Ann‐Katrin Hennemann, Vaia Pappa, Aiden Haghikia   +7 more
wiley   +1 more source

Etiopathogenesis of Immune‐Mediated Necrotizing Myopathy: A Comprehensive Review of Recent Advances

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
This review systematically clarifies that the core of IMNM begins with specific autoantibodies, which in turn trigger complement activation, immune cell infiltration, and a storm of inflammatory factors. Together, these processes induce regulatory cell death and mitochondrial dysfunction, ultimately leading to muscle fiber necrosis. Genetic factors and
Chang Gao, Wenli Li, Qingyan Liu, Guochun Wang, Qinglin Peng   +4 more
wiley   +1 more source