Results 71 to 80 of about 2,848 (185)

Antisynthetase Syndrome Associated with Sarcoidosis

Internal Medicine, 2006
A 30-year-old man complained of polyarthralgia and fatigue. The clinical findings and laboratory data included myositis, polyarthritis, interstitial pneumonia, Raynaud's phenomenon, mechanic's hand, and anti PL-7 antibody (threonyl-tRNA synthetase antibody). All of these signs were consistent with antisynthetase syndrome.
Asanuma, Yu, Koichihara, Reiko, Koyama, Shinichiro, Kawabata, Yoshinori, Kobayashi, Shio, Mimori, Tsuneyo, Moriguchi, Masato   +6 more
openaire   +3 more sources

Timing of onset affects arthritis presentation pattern in antisynthetase syndrome

, 2018
Objective To evaluate if the timing of appearance with respect to disease onset may influence the arthritis presentation pattern in antisynthetase syndrome (ASSD). Methods The patients were selected from a retrospective large international cohort of ASSD
AENAS (American and European Network of Antisynthetase Syndrome) collaborative group, Lund University.   +1 more
core   +1 more source

IVIG for refractory dysphagia in Antisynthetase syndrome: A truth hard to swallow

Clinical Case Reports, 2022
Refractory dysphasia could be the main symptom of Antisynthetase syndrome (ASS). IVIG may have a major impact in the successful treatment of dysphasia in patients with ASS.
Mais Alnoukari, Oziel Garza De La Garza, Karrar Al Gburi, Niral Patel, Henderson Lopez, Muhammad Shamim, Henry Kwang   +6 more
doaj   +1 more source

Case of late diagnosis of dermatomyositis with anti-synthetic syndrome

Лечащий Врач, 2021
Polymyositis (PM) and dermatomyositis (DM) are autoimmune diseases of skeletal muscles of unknown etiology, which belong to systemic diseases of the connective tissue and are collectively called «idiopathic inflammatory myopathies».
L. A. Smirnova, O. V. Simonova, E. N. Sukhikh   +2 more
doaj   +1 more source

Etiopathogenesis of Immune‐Mediated Necrotizing Myopathy: A Comprehensive Review of Recent Advances

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
This review systematically clarifies that the core of IMNM begins with specific autoantibodies, which in turn trigger complement activation, immune cell infiltration, and a storm of inflammatory factors. Together, these processes induce regulatory cell death and mitochondrial dysfunction, ultimately leading to muscle fiber necrosis. Genetic factors and
Chang Gao, Wenli Li, Qingyan Liu, Guochun Wang, Qinglin Peng   +4 more
wiley   +1 more source

Overlap Syndrome of Antisynthetase Syndrome and Rheumatoid Arthritis: A Case Report [PDF]

, 2011
The antisynthetase syndrome is characterized by anti-Jo-1 antibody production, interstitial lung disease, inflammatory muscle disease, and, in many cases, fever, polyarthritis, Raynaud’s phenomenon, and mechanic’s hands. Joint signs and symptoms occur in
장희원, 이수곤, 하유정, 이광훈, 강윤, 박용범   +5 more
core  

Risk Factors for Recurrence of the Anti‐Synthetase Syndrome Related Interstitial Lung Disease

Immunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
ABSTRACT Purpose This current study aimed to detect the risk factors for recurrence of the anti‐synthetase syndrome related interstitial lung disease (ASSD‐ILD). Methods Patients who were diagnosed with ASSD‐ILD and achieved the improving standards after treatment at a single clinical center from January 1, 2017 to January 1, 2022 were retrospectively ...
Zhen‐Yu Ren, Xue Yang, Jing Yang, Ping Kou, Xiao‐Kui Tang   +4 more
wiley   +1 more source

Genetic Susceptibility to Antisynthetase Syndrome Associated With Single-Nucleotide Variants in the IL1B Gene That Lead Variation in IL-1β Serum Levels

Frontiers in Medicine, 2020
The antisynthetase syndrome (ASSD) is an autoimmune disorder characterized by myositis, arthritis, mechanic's hands, fever, Raynaud phenomenon, and interstitial lung disease (ILD).
Marco Antonio Ponce-Gallegos, Espiridión Ramos-Martínez, Adriana García-Carmona, Mayra Mejía, Karol J. Nava-Quiroz, Gloria Pérez-Rubio, Enrique Ambrocio-Ortiz, Montserrat I. González-Pérez, Ivette Buendía-Roldán, Jorge Rojas-Serrano, Ramcés Falfán-Valencia   +10 more
doaj   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Antisynthetase Syndrome after chikungunya infection: A case report

Clinical Case Reports, 2022
Chikungunya is an arboviral disease caused by a virus with wide geographical distribution in endemic areas. This case report documents a patient with antisynthetase syndrome post‐chikungunya infection.
Raiza Cansian Tuão, Mariana de Oliveira Macabú, Paula dos Santos Athayde, Isac Ribeiro Moulaz, Barbara Ferraço Dalmaso, Valéria Valim Cristo, Ketty Lysie Libardi Lira Machado   +6 more
doaj   +1 more source