Results 31 to 40 of about 2,848 (185)

Pericarditis as the Initial Manifestation of Antisynthetase Syndrome: A Case Report

Case Reports in Rheumatology
Antisynthetase syndrome is a subtype of idiopathic inflammatory myopathy characterized by clinical manifestations that include myositis with a distinctive muscle biopsy pattern. Cardiac involvement has traditionally been considered a rare feature of this
Gianni Lucchetti, Per Sundbom
doaj   +2 more sources

18F-FDG PET/CT IN ANTISYNTHETASE SYNDROME: CASE REPORT

Hematology, Transfusion and Cell Therapy
Introduction/Justification: Antisynthetase syndrome is an autoimmune pathology characterized by production of autoantibodies against aminoacyl tRNA synthetase, mainly anti-Jo-1. Report: Male patient presenting a clinical picture of polyarthritis in hands
Felipe Piccarone Gonçalves Ribeiro, Dihego Ferreira dos Santos, Bárbara Juarez Amorim, Allan de Oliveira Santos, Elba Cristina Sá de Camargo Etchebehere, Ludmila Santiago Almeida, Celso Darío Ramos, Mariana da Cunha Lopes de Lima   +7 more
doaj   +2 more sources

Severe finger necrosis in antisynthetase syndrome with positive anti‐OJ antibodies [PDF]

Clinical Case Reports
Key Clinical Message In a patient with anti‐aminoacyl tRNA synthetase antibody and anti‐OJ antibody syndrome, interventions likes warming, prostaglandins, and antiplatelets failed. However, prednisolone pulse treatment rapidly halted disease progression.
Yugo Horiuchi, Kenichi Hashimoto, Ryochi Yoshida, Akinori Sekizawa, Akatsuki Kubota, Meiko Maeda, Tatsushi Toda, Yuji Tanaka   +7 more
doaj   +2 more sources

An Exploratory Analysis of Antibody Dynamics in Isolated Organ Involvement of Antisynthetase Syndrome: A Single-Center Experience. [PDF]

ACR Open Rheumatol
Objective To characterize longitudinal anti–aminoacyl–tRNA synthetase (anti‐ARS) antibody kinetics in antisynthetase syndrome (ASyS) with isolated organ involvement (IOI) and examine associations with clinical trajectories versus multiple organ involvement (MOI).
Suzuki T, Yamaji M, Harada H, Kawahata K.   +3 more
europepmc   +2 more sources

Hypereosinophilia Associated With Antisynthetase Syndrome With Anti-Ro52/PL12 Co-Positivity: An Unusual Presentation. [PDF]

Clin Case Rep
ABSTRACT Hypereosinophilia is uncommon in ASS and this presentation makes diagnosis more challenging. Anti‐PL12's role in the severity of ILD is controversial but its association with anti‐Ro52 seems to give a more serious disease phenotype. African ethnicity could be a negative prognostic factor, associated with lung disease severity.
Kapuczinski A, Léon M, Rossi C, Bondue B, Demeulenaere N.   +4 more
europepmc   +2 more sources

Antisynthetase Syndrome Mimicking Pulmonary Infection: A Diagnostic Lesson From County-Managed Hospital. [PDF]

Clin Case Rep
ABSTRACT Antisynthetase syndrome (ASS) is a rare chronic autoimmune disease classified as a distinct subtype of idiopathic inflammatory myopathy, characterized by the presence of anti–aminoacyl‐transfer RNA synthetase (anti‐ARS) antibodies. Typical clinical features include myositis, interstitial lung disease (ILD), arthritis, fever, mechanic's hands ...
Cheng J.
europepmc   +2 more sources

The antisynthetase syndrome [PDF]

Baylor University Medical Center Proceedings, 2020
Antisynthetase syndrome is an autoimmune disease affecting multiple organ systems that was first described as a triad of polymyositis, interstitial lung disease, and the presence of autoantibodies to aminoacyl-transfer ribonucleic acid synthetases. We describe a patient who developed respiratory symptoms following fume exposures. Following a prednisone
Drew, Robinson, Beth, Scholz
openaire   +2 more sources

Anti–Jo-1–Positive Antisynthetase Syndrome and Myocarditis: An Underrecognized Clinical Presentation

Annals of Internal Medicine: Clinical Cases, 2023
Antisynthetase syndrome is a distinct entity of overlap myositis in adults and is characterized by muscle weakness, arthritis, mechanic's hands, interstitial lung disease, and Raynaud phenomenon.
Rania Al Asmar, Rabia Cheema, Samera Vaseer, Ira Targoff, Mary Beth Humphrey   +4 more
doaj   +1 more source

Atypical Presentation of Antisynthetase Syndrome: A Case Report

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2023
Antisynthetase syndrome is characterized by autoantibodies against one of many aminoacyl transfer RNA synthetases. The clinical features include interstitial lung disease (ILD), non-erosive arthritis, Raynaud’s phenomenon, myositis, unexplained fever ...
Shalesh Rohatgi, Prajwal Rao, Satish Nirhale, Pravin Naphade   +3 more
doaj   +1 more source

The Antisynthetase Syndrome [PDF]

The American Journal of Medicine, 2011
The antisynthetase syndrome (ASS) was first described by Marguerie and coworkers in 1990 as a triad of polymyositis, diffuse interstitial lung disease (ILD) and serum autoantibodies to aminoacyl transfer RNA synthetases (anti-ARS) (1). Later, cohort studies have indicated that 20-25 % of patients diagnosed with polymyositis (PM) or dermatomyositis (DM)
Jan Tore, yvind Molberg
openaire   +2 more sources