Results 31 to 40 of about 2,373 (163)
Drug-induced antisynthetase syndrome [PDF]
Postgraduate Medical Journal, 1997 Summary We present a case of antisynthetase syndrome whose predominant feature was fibrosing alveolitis and which may have been drug-induced. This responded well to steroids and cyclophosphamide.
D R, Thickett, A B, Millar
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Coronary artery dilation associated with anti-synthetase syndrome in an adolescent
Pediatric Rheumatology Online Journal, 2019 Background Idiopathic inflammatory myopathies (IIM) are a group of systemic autoimmune disorders primarily affecting skeletal muscle. Pediatric coronary artery dilation is frequently discussed in Kawasaki disease.
Karim Asi +2 more
doaj +1 more source
Antisynthetase Syndrome: The Classical Phenotype With a Twist. [PDF]
Cureus, 2023 Antisynthetase syndrome is a systemic autoimmune rheumatic disease characterized by multiple organ involvement, including interstitial lung disease, myositis, non-erosive arthritis, fever, Raynaud's phenomenon, "mechanic's hands," and the presence of autoantibodies against aminoacyl-tRNA synthetases, mainly anti-Jo1 (histidyl) antibodies. Patients with
Betsikos A +4 more
europepmc +3 more sources
The Diagnosis and Treatment of Antisynthetase Syndrome [PDF]
Clinical Pulmonary Medicine, 2016 Anti-synthetase syndrome is an autoimmune condition, characterized by antibodies directed against an aminoacycl transfer RNA synthetase along with clinical features that can include interstitial lung disease, myositis, Raynaud's phenomenon, and arthritis.
Leah J, Witt +2 more
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Clinical utility of anti‐cytosolic 5’‐nucleotidase 1A antibody in idiopathic inflammatory myopathies
Annals of Clinical and Translational Neurology, 2021 Objective To define the clinicopathologic features and diagnostic utility associated with anti‐cytosolic 5′‐nucleotidase 1A (NT5C1A) antibody seropositivity in idiopathic inflammatory myopathies (IIMs).
Chiseko Ikenaga +13 more
doaj +1 more source
Journal of Medical Case Reports, 2022 Background Overlap syndromes account for about 25% of autoimmune diseases. They are many possible combinations of known autoimmune diseases increasingly diagnosed with the identification of of a large number of autoantibodies.
W. S. Weerasinghe, Chandrika Jayasinghe
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European Journal of Case Reports in Internal Medicine, 2022 A patient with antisynthetase syndrome with pulmonary and muscular involvement was treated with immunosuppressive agents without corticosteroids. Rituximab was added to mycophenolate mofetil therapy with improvement in lung functional and imaging ...
Agnieszka Ewa Sieradzka +2 more
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Respirology Case Reports, 2023 Immune checkpoint inhibitors (ICIs) unleash potent anti‐tumour responses but with frequent off‐target immune‐mediated adverse events (irAE). ICIs can induce a spectrum of rheumatologic manifestations including inflammatory arthritis, Sjögren's syndrome ...
Peter T. Bell +4 more
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Antisynthetase syndrome: a case report [PDF]
Quantitative Imaging in Medicine and Surgery, 2016 The case is about a 48-year-old man with one week history of progressively worsening shortness of breath and reduced exercise tolerance. Laboratory investigations revealed raised ESR, creatine kinase (CK) and positive anti-aminoacyl-transfer RNA synthetase.
Mehwish Asif, Qureshi +3 more
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Case Reports in Rheumatology, 2023 Antisynthetase syndrome is a rare autoimmune disease within the subset of idiopathic inflammatory myopathies. The diagnostic criteria include the presence of an aminoacyl-tRNA synthetase antibody, and typical clinical findings, including myositis ...
Anusha Vege, Jesse Beery, Areeba Kara
doaj +1 more source