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Antisynthetase syndrome is a rare autoimmune disease within the subset of idiopathic inflammatory myopathies. The diagnostic criteria include the presence of an aminoacyl-tRNA synthetase antibody, and typical clinical findings, including myositis ...
Anusha Vege, Jesse Beery, Areeba Kara
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Diffuse Alveolar Hemorrhage in a Patient with Antisynthetase Syndrome
An alveolar hemorrhage case is reported as the initial manifestation of antisynthetase syndrome in a 40-year-old man, who is admitted to the Emergency Department for diagnostic approach of chronic cough and progressive dyspnea.
D. A. Vargas-Gutiérrez +7 more
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We report the case of a 39-year-old female who presented with breathlessness on exertion, cough, myalgias for the past 6 months and fever for 1 month. Chest X-ray revealed bilateral multilobar consolidation.
V Arun Raja +6 more
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IVIG for refractory dysphagia in Antisynthetase syndrome: A truth hard to swallow [PDF]
Refractory dysphasia could be the main symptom of Antisynthetase syndrome (ASS). IVIG may have a major impact in the successful treatment of dysphasia in patients with ASS.
Mais Alnoukari +6 more
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18F-FDG PET/CT IN ANTISYNTHETASE SYNDROME: CASE REPORT
Introduction/Justification: Antisynthetase syndrome is an autoimmune pathology characterized by production of autoantibodies against aminoacyl tRNA synthetase, mainly anti-Jo-1. Report: Male patient presenting a clinical picture of polyarthritis in hands
Felipe Piccarone Gonçalves Ribeiro +7 more
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Severe finger necrosis in antisynthetase syndrome with positive anti‐OJ antibodies
Key Clinical Message In a patient with anti‐aminoacyl tRNA synthetase antibody and anti‐OJ antibody syndrome, interventions likes warming, prostaglandins, and antiplatelets failed. However, prednisolone pulse treatment rapidly halted disease progression.
Yugo Horiuchi +7 more
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The antisynthetase syndrome [PDF]
Antisynthetase syndrome is an autoimmune disease affecting multiple organ systems that was first described as a triad of polymyositis, interstitial lung disease, and the presence of autoantibodies to aminoacyl-transfer ribonucleic acid synthetases. We describe a patient who developed respiratory symptoms following fume exposures. Following a prednisone
Drew, Robinson, Beth, Scholz
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[Antisynthetase syndrome - a case report]. [PDF]
Twenty-eight year-old woman with predominant signs of polymyositis, pulmonary interstitium involvement and with positive anti-Jo1 antibodies was suspected for antisynthetase syndrome. Over the next three months sores and ulcerations have appeared at the fingertips.
Prus, Višnja +6 more
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Difficulties in the diagnosis of antisynthetase syndrome [PDF]
Antisynthetase syndrome is a rare subtype of idiopathic inflammatory myopathies, characterised by co-ocurrence of myositis, arthritis, interstitial lung disease, Raynaud phenomenon, fever and mechanic’s hands.
Opinc, Aleksandra; Department of Rheumatology, Medical University of Lodz, Żeromskiego 113, 90-549 Łódź, Poland +1 more
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Anti–Jo-1–Positive Antisynthetase Syndrome and Myocarditis: An Underrecognized Clinical Presentation
Antisynthetase syndrome is a distinct entity of overlap myositis in adults and is characterized by muscle weakness, arthritis, mechanic's hands, interstitial lung disease, and Raynaud phenomenon.
Rania Al Asmar +4 more
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