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Case Report: Anti-PL-12 Antisynthetase syndrome complicated by natural killer/T cell non-Hodgkin’s lymphoma [PDF]
Frontiers in ImmunologyAntisynthetase syndrome (ASS) is a systemic autoimmune disorder classified as a subtype of the idiopathic inflammatory myopathies (IIM). The condition is defined by the presence of mutually exclusive autoantibodies directed against an aminoacyl-tRNA ...
Kun Li +4 more
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Antisynthetase Syndrome With Paraneoplastic Antibodies. [PDF]
Cureus, 2023 Antisynthetase syndrome (ASyS) is an uncommon systemic autoimmune disorder characterized by the presence of autoantibodies targeting aminoacyl-transfer RNA (tRNA) synthetase. The syndrome displays a diverse range of clinical manifestations affecting multiple organs, thereby posing a diagnostic challenge.
Pokharel A +4 more
europepmc +3 more sources
Unusual presentation of antisynthetase syndrome: a case series and review of the literature
Journal of Medical Case Reports, 2023 Background Antisynthetase syndrome is an inflammatory myopathy that is characterized by the presence of anti-aminoacyl-tRNA synthetase antibodies. Only 30% of those who suffer from the disease can be identified.
Juan Estrada-Maya +9 more
doaj +2 more sources
Antisynthetase syndrome: a case report [PDF]
Quantitative Imaging in Medicine and Surgery, 2016 The case is about a 48-year-old man with one week history of progressively worsening shortness of breath and reduced exercise tolerance. Laboratory investigations revealed raised ESR, creatine kinase (CK) and positive anti-aminoacyl-transfer RNA synthetase.
Mehwish Asif, Qureshi +3 more
openaire +3 more sources
RMD Open, 2023 No standardised and universal treatment is available for antisynthetase syndrome. In particular, there is an unmet need for a single efficient treatment acting on its various manifestations, including interstitial lung disease, myositis and polyarthritis.
Jean Dudler, Fleur Baumann Benvenuti
doaj +2 more sources
Reclassification of Seronegative Rheumatoid Arthritis as Anti-PL-12 Antisynthetase Syndrome with Interstitial Lung Disease and Joint Involvement–Case Report [PDF]
ReportsBackground and Clinical Significance: Antisynthetase syndrome (ASyS) is a rare autoimmune entity defined by the presence of anti-aminoacyl-t ribonucleic acid (RNA) synthetase autoantibodies and classically associated with a triad of interstitial lung ...
Diana Elena Cosău +8 more
doaj +2 more sources
Antisynthetase Syndrome: The Classical Phenotype With a Twist. [PDF]
Cureus, 2023 Antisynthetase syndrome is a systemic autoimmune rheumatic disease characterized by multiple organ involvement, including interstitial lung disease, myositis, non-erosive arthritis, fever, Raynaud's phenomenon, "mechanic's hands," and the presence of autoantibodies against aminoacyl-tRNA synthetases, mainly anti-Jo1 (histidyl) antibodies. Patients with
Betsikos A +4 more
europepmc +3 more sources
Journal of Clinical and Scientific Research, 2019 We report the case of a 39-year-old female who presented with breathlessness on exertion, cough, myalgias for the past 6 months and fever for 1 month. Chest X-ray revealed bilateral multilobar consolidation.
V Arun Raja +6 more
doaj +3 more sources
Diffuse Alveolar Hemorrhage in a Patient with Antisynthetase Syndrome
Case Reports in Rheumatology, 2019 An alveolar hemorrhage case is reported as the initial manifestation of antisynthetase syndrome in a 40-year-old man, who is admitted to the Emergency Department for diagnostic approach of chronic cough and progressive dyspnea.
D. A. Vargas-Gutiérrez +7 more
doaj +2 more sources
Case Reports in Rheumatology, 2023 Antisynthetase syndrome is a rare autoimmune disease within the subset of idiopathic inflammatory myopathies. The diagnostic criteria include the presence of an aminoacyl-tRNA synthetase antibody, and typical clinical findings, including myositis ...
Anusha Vege, Jesse Beery, Areeba Kara
doaj +2 more sources