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A case of antisynthetase syndrome [PDF]
Respiratory complaints alone or in association with musculoskeletal complaints can be the predominant presenting feature of antisynthetase syndrome. Therefore, antibodies to cellular antigens should be evaluated in such clinical settings.
Clio P. Mavragani +1 more
doaj +5 more sources
A multidisciplinary approach to the diagnosis of antisynthetase syndrome [PDF]
Antisynthetase syndrome is a subtype of idiopathic inflammatory myopathy, strongly associated with the presence of interstitial lung disease. Diagnosis is made by identifying myositis-specific antibodies directed against aminoacyl tRNA synthetase, and ...
Matthew Wells +10 more
doaj +6 more sources
Syndrome in question: antisynthetase syndrome (anti-PL-7) [PDF]
: Antisynthetase syndrome is a rare autoimmune disease characterized by interstitial lung disease and/or inflammatory myositis, with positive antisynthetase antibodies (anti-Jo-1, anti-PL-7, anti-PL-12, ZO, OJ, anti-KE or KS).
Ana Cláudia Cavalcante Esposito +2 more
doaj +6 more sources
A Rare Case Report of Antisynthetase Syndrome With Progressive Myopathy and Interstitial Lung Disease in a 38‐Year‐Old Male [PDF]
Antisynthetase syndrome is a rare autoimmune disorder characterized by a range of clinical features, most commonly associated with autoantibodies targeting aminoacyl‐tRNA synthetases.
Masab Ali +4 more
doaj +3 more sources
Nailfold videocapillaroscopy in antisynthetase syndrome [PDF]
A 57-year-old woman with a diagnosis of antisynthetase syndrome (ASSD) underwent a nailfold videocapillaroscopy (NVC) showing a scleroderma pattern. Alterations in capillary morphology have been reported in adults with inflammatory myositis (IM) but only
G. Cassone +6 more
doaj +8 more sources
Antisynthetase Syndrome with Severe Interstitial Lung Disease in Pregnancy
Antisynthetase syndrome is a rare multisystem autoimmune disorder which clinically manifests with myositis, arthritis, interstitial lung disease, Raynaud phenomenon, and skin hyperkeratosis. Lung involvement represents the most severe form of disease and
Catalina I. Dumitrascu +4 more
doaj +2 more sources
Objective: Antisynthetase syndrome is a condition that includes interstitial lung disease and inflammatory myositis in its definition. The interstitial lung disease of this syndrome can vary in severity and if not identified soon enough, can lead to ...
Michelle Cancel, M.D. +1 more
doaj +2 more sources
Polymyositis (PM) and dermatomyositis (DM) are autoimmune skeletal muscle diseases of unknown etiology, which are referred to as systemic connective tissue diseases and united under the common term Tidiopathic inflammatory myopathiesy.
Olga Alekseyevna Antelava +5 more
doaj +3 more sources
Efficacy and safety of telitacicept in patients with progressive interstitial lung disease associated with antisynthetase syndrome, rheumatoid arthritis, or Sjögren’s syndrome: a prospective observational study [PDF]
Background Interstitial lung disease (ILD) is a severe complication of antisynthetase syndrome, rheumatoid arthritis, and Sjögren’s syndrome, contributing significantly to patient mortality. Standard treatment options remain limited. This study evaluated
Xue Chen +6 more
doaj +2 more sources
Echocardiographic characteristics of patients with antisynthetase syndrome
Right ventricular (RV) dysfunction and pulmonary hypertension (PH) occurs in approximately one‐third of patients with interstitial lung disease (ILD) and is associated with reduced 6‐minute walk distance (6MWD), and increased hospitalizations and ...
Jaimie L. Bryan +11 more
doaj +3 more sources

