Clinical profiles associated with rapidly progressive interstitial lung disease in antisynthetase syndrome: A multicentric cohort study (TYPASS study). [PDF]
Abstract Objectives To assess factors associated with rapidly progressive interstitial lung disease (ILD) (RP‐ILD) at time of ILD diagnosis in a multicentric retrospective cohort study of antisynthetase syndrome (ASyS). We used a complementary unsupervised approach, hierarchical clustering, to delineate distinct phenotypes among ASyS patients with ILD.
Billotte M +16 more
europepmc +2 more sources
ANTISYNTHETASE SYNDROME: COURSE OF A RARE DISEASE ON EXAMPLE OF CLINICAL CASE
Systemic disorders of connective tissue refer to rare and poorly studied diseases. This group of diseases associated with the variable course and makes it interesting for either medical scientists and researchers or practitioner.
Boateng H. K. +2 more
doaj +2 more sources
An atypical presentation of antisynthetase syndrome
Mayank Kapoor +2 more
doaj +2 more sources
Antisynthetase syndrome (AS) is a rare autoimmune disease characterized by autoantibodies against aminoacyl-transfer RNA synthetase and clinical features which can include interstitial lung disease (ILD).
Soran Peshbahar +2 more
doaj +1 more source
A case of antisynthetase syndrome with chilblains‐like lesions and microangiopathy
We present the case of a 50‐year‐old woman with febrile myalgia, chilblains‐like lesions, and cough. Antinuclear antibodies and anti‐PL‐12 antisynthetase autoantibodies were found in complementary examinations.
Tom Abrassart +3 more
doaj +1 more source
Coexistence of two antisynthetases in a patient with the antisynthetase syndrome [PDF]
AbstractWe describe the immunologic findings in a patient with the antisynthetase syndrome characterized by prominent arthritis, lung fibrosis, and subclinical myositis. At disease onset and during the followup, this patient's serum showed 2 different subsets of antisynthetase autoantibodies: anti–Jo‐1, which reacted with histidyl–transfer RNA (tRNA ...
C, Gelpí +4 more
openaire +2 more sources
273rd ENMC International workshop:Clinico-Sero-morphological classification of the Antisynthetase syndrome. Amsterdam, The Netherlands, 27-29 October 2023 [PDF]
Among the idiopathic inflammatory myopathies, patients harbouring an Antisynthetase syndrome exhibit a unique clinical picture, with characteristic signs such as myositis, interstitial lung disease, arthritis, rash, and/or fever.
Holzer, Marie-Therese +24 more
core +5 more sources
Difficulties in the diagnosis of antisynthetase syndrome
Antisynthetase syndrome is a rare subtype of idiopathic inflammatory myopathies, characterised by co-ocurrence of myositis, arthritis, interstitial lung disease, Raynaud phenomenon, fever and mechanic’s hands.
Opinc, Aleksandra; Department of Rheumatology, Medical University of Lodz, Żeromskiego 113, 90-549 Łódź, Poland +1 more
core +1 more source
Nonspecific interstitial pneumonia revealing an antisynthetase syndrome
One of the most common interstitial lung diseases in antisynthetase syndrome is nonspecific interstitial pneumonia (NSIP). A 49-year-old woman presented with slow progression exertional dyspnea, myalgia, and arthralgia.
Nedia Moussa +5 more
doaj +1 more source
Premature live birth in a woman with antisynthetase syndrome following recurrent miscarriages
Antisynthetase syndrome (anti-SS) is a rare systemic autoimmune disease characterised by autoantibodies against aminoacyl-tRNA synthetases manifesting as one or more components of the classic triad: interstitial lung disease, arthritis and myositis ...
Chakradeo, Katrina +3 more
core +1 more source

