Results 41 to 50 of about 1,527,893 (148)

Coronary artery dilation associated with anti-synthetase syndrome in an adolescent

open access: yesPediatric Rheumatology Online Journal, 2019
Background Idiopathic inflammatory myopathies (IIM) are a group of systemic autoimmune disorders primarily affecting skeletal muscle. Pediatric coronary artery dilation is frequently discussed in Kawasaki disease.
Karim Asi   +2 more
doaj   +1 more source

Clinical utility of anti‐cytosolic 5’‐nucleotidase 1A antibody in idiopathic inflammatory myopathies

open access: yesAnnals of Clinical and Translational Neurology, 2021
Objective To define the clinicopathologic features and diagnostic utility associated with anti‐cytosolic 5′‐nucleotidase 1A (NT5C1A) antibody seropositivity in idiopathic inflammatory myopathies (IIMs).
Chiseko Ikenaga   +13 more
doaj   +1 more source

The Diagnosis and Treatment of Antisynthetase Syndrome [PDF]

open access: yesClinical Pulmonary Medicine, 2016
Anti-synthetase syndrome is an autoimmune condition, characterized by antibodies directed against an aminoacycl transfer RNA synthetase along with clinical features that can include interstitial lung disease, myositis, Raynaud's phenomenon, and arthritis.
Leah J, Witt   +2 more
openaire   +2 more sources

Overlapping rheumatoid arthritis and antisynthetase syndrome with secondary Sjögren’s syndrome: a case report and review of the literature

open access: yesJournal of Medical Case Reports, 2022
Background Overlap syndromes account for about 25% of autoimmune diseases. They are many possible combinations of known autoimmune diseases increasingly diagnosed with the identification of of a large number of autoantibodies.
W. S. Weerasinghe, Chandrika Jayasinghe
doaj   +1 more source

Anti‐synthetase syndrome associated interstitial lung disease after combination dual immune checkpoint inhibition

open access: yesRespirology Case Reports, 2023
Immune checkpoint inhibitors (ICIs) unleash potent anti‐tumour responses but with frequent off‐target immune‐mediated adverse events (irAE). ICIs can induce a spectrum of rheumatologic manifestations including inflammatory arthritis, Sjögren's syndrome ...
Peter T. Bell   +4 more
doaj   +1 more source

A Case of Anti-Synthetase Syndrome Successfully Treated with Mycophenolate Mofetil and Rituximab but No Corticosteroids

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2022
A patient with antisynthetase syndrome with pulmonary and muscular involvement was treated with immunosuppressive agents without corticosteroids. Rituximab was added to mycophenolate mofetil therapy with improvement in lung functional and imaging ...
Agnieszka Ewa Sieradzka   +2 more
doaj   +1 more source

Antisynthetase Syndrome Masquerading as Hypersensitivity Pneumonitis

open access: yesRespiration, 2021
Interstitial lung diseases (ILDs) cover a wide heterogeneous group of disorders, both of unknown and known causes. Accurate diagnosis is essential but, at the same time, presents many challenges. Typically, the distinction between idiopathic pulmonary fibrosis and fibrotic hypersensitivity pneumonitis (HP) can prove extremely difficult.
Tzilas, Vasilios   +2 more
openaire   +3 more sources

Antisynthetase Syndrome: The Classical Phenotype With a Twist

open access: yesCureus, 2023
Antisynthetase syndrome is a systemic autoimmune rheumatic disease characterized by multiple organ involvement, including interstitial lung disease, myositis, non-erosive arthritis, fever, Raynaud's phenomenon, "mechanic's hands," and the presence of autoantibodies against aminoacyl-tRNA synthetases, mainly anti-Jo1 (histidyl) antibodies. Patients with
Betsikos, Achilleas   +4 more
openaire   +2 more sources

Influence of MUC5B gene on antisynthetase syndrome [PDF]

open access: yesScientific Reports, 2020
AbstractMUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity pneumonitis (CHP). Due to this, we evaluated the implication of MUC5B rs35705950 in antisynthetase syndrome (ASSD), a pathology ...
Raquel López-Mejías   +36 more
openaire   +10 more sources

Antisynthetase syndrome after acute massive inhalation of wood and paint dust

open access: yes, 2016
Antisynthetase syndrome after acute massive inhalation of wood and paint ...
GGD Campos (2546200)   +5 more
core   +1 more source

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