Results 41 to 50 of about 2,373 (163)

A Review of Antisynthetase Syndrome-Associated Interstitial Lung Disease [PDF]

International Journal of Molecular Sciences
Aamir Ajmeri, Puja Patel
exaly   +2 more sources

ANTISITETASE SYNDROME: SERIES OF CASES DIAGNOSED IN A COMARCAL HOSPITAL

Galicia Clínica
Introduction: The antisynthetase syndrome is a rare autoimmune disease that affects multiple organs. It typically presents with polymyositis, interstitial lung disease, and antisynthetase autoantibodies.
Ignacio Lasierra Lavilla, Julien Paola Caballero Castro, Mario Nicolás Albani Pérez, Juan Salas Jarque, Lidia Estopiñan Fortea, Ignacio Vallés Tormo   +5 more
doaj   +1 more source

Antisynthetase Syndrome Masquerading as Hypersensitivity Pneumonitis

Respiration, 2021
Interstitial lung diseases (ILDs) cover a wide heterogeneous group of disorders, both of unknown and known causes. Accurate diagnosis is essential but, at the same time, presents many challenges. Typically, the distinction between idiopathic pulmonary fibrosis and fibrotic hypersensitivity pneumonitis (HP) can prove extremely difficult.
Tzilas, Vasilios, Sfikakis, Petros P., Bouros, Demosthenes   +2 more
openaire   +3 more sources

Influence of MUC5B gene on antisynthetase syndrome [PDF]

Scientific Reports, 2020
AbstractMUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity pneumonitis (CHP). Due to this, we evaluated the implication of MUC5B rs35705950 in antisynthetase syndrome (ASSD), a pathology ...
Raquel López-Mejías, Sara Remuzgo-Martínez, Fernanda Genre, Verónica Pulito-Cueto, Sonia M. Fernández Rozas, Javier Llorca, David Iturbe Fernández, Víctor M. Mora Cuesta, Norberto Ortego-Centeno, Nair Pérez Gómez, Antonio Mera-Varela, Julia Martínez-Barrio, Francisco Javier López-Longo, Verónica Mijares, Leticia Lera-Gómez, María Piedad Usetti, Rosalía Laporta, Virginia Pérez, Alicia De Pablo Gafas, María Aránzazu Alfranca González, Jaime Calvo-Alén, Fredeswinda Romero-Bueno, Olga Sanchez-Pernaute, Laura Nuno, Gema Bonilla, Alejandro Balsa, Fernanda Hernández-González, Ignacio Grafia, Sergio Prieto-González, Javier Narvaez, Ernesto Trallero-Araguas, Albert Selva-O’Callaghan, Oreste Gualillo, Santos Castañeda, Lorenzo Cavagna, José M. Cifrian, Miguel A. González-Gay   +36 more
openaire   +10 more sources

Early predominant inflammatory myopathy in anti‐glycyl‐tRNA synthetase (EJ) antibody positive antisynthetase syndrome

Clinical Case Reports, 2021
It is important to consider antisynthetase syndrome in the differential diagnosis of patients presenting with weakness, respiratory distress, and a constellation of complaints spanning multiple organ systems, as this will change clinical management.
Robin Warner, Derrece Reid
doaj   +1 more source

Improved Detection of Myositis‐Specific Autoantibodies Using Luciferase Immunoprecipitation Systems Assay: Comparison With Line Blot and Conventional Immunoprecipitation

Arthritis &Rheumatology, EarlyView.
Objective Myositis‐specific autoantibodies guide the diagnosis and classification of idiopathic inflammatory myopathies, but current immunoassays vary in accuracy, particularly for autoantibodies associated with interstitial lung disease. To compare the performance of the luciferase immunoprecipitation systems (LIPS) assay with line blot and ...
Peter D. Burbelo, Iago Pinal‐Fernandez, Maria Casal‐Dominguez, Xin Tian, Shijinqiu Gao, Neha Gupta, Eric W. Robbins, John A. Chiorini, Christopher A. Mecoli, Lisa Christopher‐Stine, Livia Casciola‐Rosen, Andrew L. Mammen, Sonye K. Danoff, Anthony F. Suffredini, Julio A. Huapaya   +14 more
wiley   +1 more source

Development of myasthenia gravis 8 years after interstitial lung disease associated with antisynthetase (anti‐EJ antibody) syndrome

Clinical Case Reports, 2017
Key Clinical Message Patients with antisynthetase‐positive interstitial lung disease (ILD) alone sometimes develop myositis during follow‐up, but myasthenia gravis (MG) overlapping on antisynthetase syndrome is unusual.
Takashi Ishiguro, Naho Kagiyama, Eriko Kawate, Kyuto Odashima, Yotaro Takaku, Kazuyoshi Kurashima, Noboru Takayanagi   +6 more
doaj   +1 more source

Pregnancy in CTD‐interstitial lung disease: Current evidence, clinical challenges, and a proposed management algorithm

Rheumatology &Autoimmunity, EarlyView.
Summary of pregnancy management in CTD‐ILD across preconception, antenatal, and postpartum phases, emphasizing risk stratification and multidisciplinary care. 6MWT, 6‐min walk test; CTD‐ILD: connective tissue disease‐interstitial lung disease; DLCO, diffusion capacity of the lung for carbon monoxide; FVC, forced vital capacity; MDT, multidisciplinary ...
Khaled Aldhuaina, Ghaydaa Aldabie, Mohammad Abdulsalam, Ali Jawad   +3 more
wiley   +1 more source

Antisynthetase syndrome presenting as interstitial lung disease: a case report

Journal of Medical Case Reports, 2019
Background Antisynthetase syndrome is a relatively uncommon entity, and can be easily missed if not specifically looked for in adults whose initial presentation is with interstitial lung disease. Its presentation with interstitial lung disease alters its
Aliena Badshah, Iqbal Haider, Shayan Pervez, Mohammad Humayun   +3 more
doaj   +1 more source

COVID‐19 Vaccination Is Not Associated With the Development of Idiopathic Inflammatory Myositis in US Veterans

Arthritis Care &Research, Volume 78, Issue 8, Page 1078-1085, August 2026.
Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández, Naomi Schlesinger, Jorge Rojas, Jessica A. Walsh, Tawnie J. Braaten, Gary A. Kunkel, Makoto Jones, Brian C Sauer, Julio Facelli, Grant W. Cannon, Dorota Lebiedz‐Odrobina   +10 more
wiley   +1 more source