Results 91 to 100 of about 61,173 (287)

No Increased Risk of Thromboembolic Events During 6‐Month Treatment With Baricitinib in Patients With Alopecia Areata

open access: yes
International Journal of Dermatology, EarlyView.
Giacomo Caldarola   +8 more
wiley   +1 more source

Changes in Plasma Levels of Natural Anticoagulants in Disseminated Intravascular Coagulation: High Prognostic Value of Antithrombin and Protein C in Patients with Underlying Sepsis or Severe Infection

open access: yesAnnals of Laboratory Medicine, 2014
Background Dysfunctional natural anticoagulant systems enhance intravascular fibrin for mation in disseminated intravascular coagulation (DIC), and plasma levels of natural anti coagulants can be used in the diagnosis and prognosis of DIC.
Q. Choi   +3 more
semanticscholar   +1 more source

Combined Antithrombin and Heparin Supplementation to Blood for Restoring Heparin Responsiveness After Andexanet Alfa Exposure: An In Vitro Model

open access: yeseJHaem, Volume 7, Issue 1, February 2026.
ABSTRACT Background: Andexanet alfa, a Gla‐domainless mutant factor Xa (GDXa), reverses oral FXa inhibitors but can cause severe heparin resistance during cardiopulmonary bypass (CPB). Antithrombin (AT) supplementation may mitigate this effect, though dosing evidence is limited. Methods We evaluated in vitro the effectiveness of combined heparin and AT
Amir L. Butt   +6 more
wiley   +1 more source

Clinical Outcomes of Patients Hospitalized for Conventional Pacemaker Implantation With Protein‐Energy Malnutrition

open access: yesJournal of Arrhythmia, Volume 42, Issue 1, February 2026.
Protein‐energy malnutrition (PEM) was linked to higher in‐hospital mortality, longer hospital stays, and increased complications in patients undergoing pacemaker implantation. ABSTRACT Introduction The impact of protein‐energy malnutrition (PEM) on patients hospitalized for conventional pacemaker implantation remains poorly understood.
Phuuwadith Wattanachayakul   +7 more
wiley   +1 more source

A Robust Heparin‐Mimicking Polyglycerol‐Based Coating for Blood‐Contacting Devices with Long‐Term Hemocompatibility and Preliminary Anti‐Inflammatory Properties

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 2, 14 January 2026.
A robust heparin‐mimicking coating based on sulfated polyglycerol is constructed via layer‐by‐layer assembly on bloodcontacting surfaces. The coating exhibits long‐term anticoagulant and anti‐inflammatory properties by resisting protein adsorption, preventing platelet activation, and suppressing immune responses, offering a promising strategy for ...
Kunpeng Liu   +3 more
wiley   +1 more source

Conformational Activation of Antithrombin by Heparin Involves an Altered Exosite Interaction with Protease*

open access: yesJournal of Biological Chemistry, 2014
Background: Exosites are known to mediate heparin allosteric activation of antithrombin. Results: Mutagenesis revealed that an exosite differentially contributes to antithrombin reactivity with factors Xa/IXa in unactivated and heparin-activated states ...
G. Izaguirre   +7 more
semanticscholar   +1 more source

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour   +14 more
wiley   +1 more source

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