Results 91 to 100 of about 61,173 (287)
Mechanism Of The Inactivation Of Trypsin By Antithrombin III [PDF]
Åke Danielsson, Ingemar Björk
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Background Dysfunctional natural anticoagulant systems enhance intravascular fibrin for mation in disseminated intravascular coagulation (DIC), and plasma levels of natural anti coagulants can be used in the diagnosis and prognosis of DIC.
Q. Choi +3 more
semanticscholar +1 more source
ABSTRACT Background: Andexanet alfa, a Gla‐domainless mutant factor Xa (GDXa), reverses oral FXa inhibitors but can cause severe heparin resistance during cardiopulmonary bypass (CPB). Antithrombin (AT) supplementation may mitigate this effect, though dosing evidence is limited. Methods We evaluated in vitro the effectiveness of combined heparin and AT
Amir L. Butt +6 more
wiley +1 more source
Protein‐energy malnutrition (PEM) was linked to higher in‐hospital mortality, longer hospital stays, and increased complications in patients undergoing pacemaker implantation. ABSTRACT Introduction The impact of protein‐energy malnutrition (PEM) on patients hospitalized for conventional pacemaker implantation remains poorly understood.
Phuuwadith Wattanachayakul +7 more
wiley +1 more source
Estimates of Within-Subject Biological Variation of Protein C, Antithrombin, Protein S Free, Protein S Activity, and Activated Protein C Resistance in Pregnant Women [PDF]
Ann Helen Kristoffersen +3 more
openalex +1 more source
A robust heparin‐mimicking coating based on sulfated polyglycerol is constructed via layer‐by‐layer assembly on bloodcontacting surfaces. The coating exhibits long‐term anticoagulant and anti‐inflammatory properties by resisting protein adsorption, preventing platelet activation, and suppressing immune responses, offering a promising strategy for ...
Kunpeng Liu +3 more
wiley +1 more source
Background: Exosites are known to mediate heparin allosteric activation of antithrombin. Results: Mutagenesis revealed that an exosite differentially contributes to antithrombin reactivity with factors Xa/IXa in unactivated and heparin-activated states ...
G. Izaguirre +7 more
semanticscholar +1 more source
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour +14 more
wiley +1 more source
Prothrombin protects factor Xa in the prothrombinase complex from inhibition by the heparin-antithrombin complex [PDF]
Alireza R. Rezaie
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