Results 91 to 100 of about 37,722 (251)

The Necessity of Individualized Treatment for Sepsis-Associated Disseminated Intravascular Coagulation by Infected Organ

Open Access Emergency Medicine, 2022
Makoto Kobayashi,1 Yoshimatsu Ehama,2 Suguru Hirayama2 1Intensive Care Center, Hakodate Goryoukaku Hospital, Hakodate City, Hokkaido, Japan; 2Department of Emergency Medicine, Hakodate Goryoukaku Hospital, Hakodate City, Hokkaido, JapanCorrespondence ...
Kobayashi M, Ehama Y, Hirayama S
doaj  

Formation of a covalent disulfide-linked antithrombin-albumin complex by an antithrombin variant, antithrombin “Northwick Park”.

Journal of Biological Chemistry, 1987
Antithrombin is a major proteinase inhibitor of the blood coagulation system. Its inherited deficiency or abnormality is often associated with thromboembolism. Antithrombin "Northwick Park," a functionally inactive variant antithrombin, has recently been shown by us (Lane, D.A., Flynn, A., Ireland, H., Erdjument, H., Samson, D., Howarth, D., and ...
H, Erdjument, D A, Lane, H, Ireland, M, Panico, V, Di Marzo, I, Blench, H R, Morris   +6 more
openaire   +2 more sources

Antithrombin III in the prevention of thrombotic complications in high risk patients undergoing liver transplantation

Трансплантология (Москва), 2019
Introduction. Recent studies have indicated an increased incidence of thrombotic vascular complications after liver transplantation. The reasons may be associated with surgical technique and “unbalanced” hemostasis in patients with diffuse liver diseases.
N. K. Kuznetsova, E. V. Klychnikova, S. V. Zhuravel, O. D. Olisov, I. I. Utkina, M. S. Novruzbekov, V. I. Reshetnyak   +6 more
doaj   +1 more source

Evaluation of a Point‐of‐Care Viscoelastic Coagulation Monitor (VCM Vet) and Thromboelastography (TEG) in Bonobos (Pan paniscus)

Journal of Medical Primatology, Volume 55, Issue 4, August 2026.
ABSTRACT Introduction Bonobos (Pan paniscus) are endangered and uncommon in managed care. Prothrombotic and hypofibrinolytic states are encountered with cardiovascular disease, ischemic stroke, and neoplasia. Materials and Methods Twelve bonobos from one institution were evaluated during anesthetized exams.
Megan M. Roeder, Priya Bapodra‐Villaverde, Lauren E. Mumm, Alex M. Lynch, Laura R. Culbreth, Megan L. Cabot, Timothy A. Georoff, Larry J. Minter   +7 more
wiley   +1 more source

Natural History of Chronic Kidney Disease in Sickle Cell Disease

American Journal of Hematology, Volume 101, Issue 7, Page 1456-1477, July 2026.
ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley   +1 more source

Antithrombin: Deficiency, Diversity, and the Future of Diagnostics

Mass Spectrometry Reviews, Volume 45, Issue 4, Page 745-768, July/August 2026.
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt, Christa M. Cobbaert, L. Renee Ruhaak   +2 more
wiley   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, Volume 45, Issue 4, Page 800-828, July/August 2026.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

Defects of splicing in antithrombin deficiency [PDF]

, 2017
Background: There is increasing evidence supporting the relevance of aberrant splicing in multiple disorders. In antithrombin deficiency only 22 intronic mutations affecting splicing sites (7% of SERPINC1 mutations) are considered as splicing mutations.
Wypasek, Ewa, Entrena, Laura, Sevivas, Teresa S, Asenjo, Susana, María F. López, María E. de la Morena‐Barrio, López, María F, Javier Corral, Irene Martínez‐Martínez, Sevivas, Teresa S., Susana Asenjo, de la Morena-Barrio, María E, de la Morena-Barrio, Maria E., Corral, Javier, Ewa Wypasek, Vicente, Vicente, Lopez-Galvez, Raquel, Vicente Vicente, Martinez-Martinez, Irene, Teresa S. Sevivas, Lopez, Maria F., Raquel López‐Gálvez, Laura Entrena   +22 more
core   +1 more source

Variability in ACT Response to Standard UFH Bolus During PCI: A Prospective Study on Determinants of Subtherapeutic Anticoagulation

Catheterization and Cardiovascular Interventions, Volume 107, Issue 7, Page 2293-2303, June 1, 2026.
ABSTRACT Background Unfractionated heparin (UFH) remains the standard anticoagulant during percutaneous coronary intervention (PCI), with guidelines recommending a target activated clotting time (ACT) of ≥250 s. However, despite receiving a standardized bolus dose, many patients fail to achieve this target.
Manh Cuong Vu, Antonin Trimaille, Amandine Granier, Adrien Carmona, Anis Elidrissi, Marion Kibler, Laurence Jesel, Patrick Ohlmann, Laurent Sattler, Olivier Morel   +9 more
wiley   +1 more source

ROLE OF ANTITHROMBIN IN DIAGNOSTICS AND INTENSIVE THERAPY OF ACUTE DIC-SYNDROME (review of literature and evidence of actual clinical practice)

Атеротромбоз, 2017
The article considers the issues of pathogenesis, diagnostics and intensive therapy of acute DIC-syndrome with underlying dysfunction of anticoagulant system.
N. A. VOROBIEVA
doaj   +1 more source