Results 41 to 50 of about 3,507,689 (226)

The Association between the Level of Antithrombin III and Mortality in Children with Sepsis [PDF]

open access: yes, 2019
BACKGROUND: Sepsis is a significant cause of morbidity and mortality in children. The diagnosis of sepsis remains continuing to develop which determines treatment and prognostic.
Lubis, Munar   +2 more
core   +1 more source

Supplementation therapy with Antithrombin Drugs in the Combined Treatment of Sepsis

open access: yesОбщая реаниматология, 2019
Purpose — to assess the efficacy of supplementation therapy for antithrombin deficiency in the combined treatment of sepsis.Materials and methods. A prospective-retrospective study of the efficacy of supplementation therapy for antithrombin deficiency ...
I. V. Redkin   +3 more
doaj   +1 more source

Unfractionated Heparin and Low‐Molecular‐Weight Heparin in Sepsis: Anti‐Inflammatory and Anticoagulant Effects Versus No Anticoagulation—A Propensity Score‐Matched Analysis

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This propensity score‐matched study compared unfractionated heparin (UFH) and low‐molecular‐weight heparin (LMWH) in 1362 sepsis patients, finding that both significantly improved survival without increasing 90‐day bleeding risk. However, their therapeutic mechanisms differed: UFH demonstrated broader anti‐inflammatory effects by reducing IL‐6, IL‐8 ...
Peili Chen   +7 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

The antithrombin activity of [alpha]-I-protease inhibitor: The antitrypsin activity of antithrombin III

open access: yes, 1976
Antithrombin III and [alpha]-I-protease inhibitor ([alpha]-I-antitrypsin) were purified from human plasma and the cross-reactivities of the two inhibitors were examined.
Learned, L. A.   +2 more
core   +1 more source

Antithrombin activity of fucoidan. The interaction of fucoidan with heparin cofactor II, antithrombin III, and thrombin [PDF]

open access: yes, 1989
Fucoidan, poly(L-fucopyranose) linked primarily alpha 1----2 with either a C3- or a C4-sulfate, is an effective anticoagulant in vitro and in vivo (Springer, G. F., Wurzel, H. A., McNeal, G. M., Jr., Ansell, N. J., and Doughty, M. F. (1957) Proc.
Meade, J B   +3 more
core   +1 more source

Antithrombin III Regulates Complement Activity

open access: yes, 1991
Journal of Immunology, 146, 3889-3894Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY.
Linhardt, Robert J., Weiler, J.M.
core   +1 more source

Hemophilia A: An Ideal Disease for Prenatal Therapy

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada   +2 more
wiley   +1 more source

Haemostatic disorders in nonsplenectomized and splenectomized thalassaemic children [PDF]

open access: yes, 1999
1171-1177A group of 40 thalassaemic patients [20 splenectomized and 20 nonsplenectomized] from the Haematology Unit of Tanta University Hospital [age range: 3-14 years] were studied to identify the mechanisms by which haemorrhagic and thrombotic ...
El Sharkawy, H.M.   +2 more
core  

Pemberian Antitrombin III pada Sepsis Neonatal

open access: yesSari Pediatri, 2016
Latar belakang. Kadar antitrombin III (AT III) dalam darah rendah pada pasien sakit berat dan penurunan kadarnya berkorelasi dengan derajat penyakit. Fungsi AT III sebagai antikoagulan, mempunyai peran penting untuk mencegah disfungsi mikrovaskular dan ...
Nathanne Septhiandi   +2 more
doaj   +1 more source

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