Results 51 to 60 of about 3,507,689 (226)

Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley   +1 more source

Plasma Antithrombin III Levels in Postoperative Patients

open access: yes, 2019
Aim: To determine preoperative and postoperative plasma concentration of antithrombin III in three different disciplines of surgery as well as to carry out an inter-comparison of antithrombin III levels after major surgical procedures in orthopedic ...
Syed Nadeeem Mansoor, syed moiz nadeem
core   +1 more source

A Study of Prothrombotic Factors in Human Immunodeficiency Virus-Infected Patients

open access: yesIndian Journal of Medical Specialities, 2021
Introduction: Human immunodeficiency virus (HIV) infection has been described as a hypercoagulable state. Some studies suggest that thrombotic events may be 2–10 times more prevalent in this group than in the general population.
Meena Lanjiwar   +3 more
doaj   +1 more source

The Histidine 382 Residue Influences the Thermal Stability and Binding Propensity of the E2 Domain of Amyloid Precursor Protein

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The E2 domain of amyloid precursor protein (APP_E2) plays a central role in the protein's function. We reinvestigate how the missense mutation, ΔH382L, affects the domain's thermal stability and ligand binding propensity through differential scanning fluorometry.
Sphamandla Ndlovu   +4 more
wiley   +1 more source

Evolutionary Mechanisms of Coagulation Factors in Cetaceans During Aquatic Adaptation

open access: yesIntegrative Zoology, EarlyView.
Compared with Bos taurus, T. truncatus showed shorter prothrombin time and thrombin time but prolonged activated partial thromboplastin time, indicating pathway‐specific remodeling of coagulation. Evolutionary analyses identified 18 positively selected genes and accelerated F11 evolution, while functional assays revealed increased coagulation factor ...
Wenjun Lv   +4 more
wiley   +1 more source

Comparative study of chromatographic properties of affinity resins in respect of protein of antithrombin III

open access: yesТонкие химические технологии, 2010
This paper reports the chromatographic properties of affinity resins in respect of protein antithrombin III. The capacity of resin Toyopearl AF-Heparin was found to be higher than that of resin of Heparin-Sepharose FF.
М. А. Аzhigirova   +4 more
doaj  

Improving ARTs: Microfluidics as a Tool for Sperm Selection

open access: yesAndrology, EarlyView.
ABSTRACT Sperm selection is a critical step in assisted reproductive technology (ART), as sperm quality directly influences embryo quality. In vivo, the female reproductive tract imposes several physical and physiological barriers that favors only the most optimal spermatozoa reaching the fertilization site.
A. Pérez‐Gómez   +7 more
wiley   +1 more source

Venous Thromboembolism in Hematologic Malignancies: Incidence, Risk Factors, and the Role of Direct Oral Anticoagulants

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Thrombotic events, particularly venous thromboembolism (VTE), are a significant source of morbidity and mortality among patients with hematologic malignancies. These patients face unique challenges due to treatment‐related complications such as thrombocytopenia, coagulopathy, and heightened bleeding risk.
Mario Biglietto   +12 more
wiley   +1 more source

Cerebral infarction in a heterozygote with variant antithrombin III.

open access: yes, 1992
We report a heterozygous case of familial qualitative deficiency of antithrombin III associated with cerebral infarction. A 33-year-old man had a history of recurrent transient ischemic attacks from the age of 28.
S Nagataki   +6 more
core   +1 more source

Comparison of Protective Effects of Recombinant Antithrombin Gamma and Plasma-Derived Antithrombin on Sepsis-Induced Disseminated Intravascular Coagulation and Multiple Organ Failure

open access: yesClinical and Applied Thrombosis/Hemostasis, 2020
In Japan, the dose of the new recombinant antithrombin III concentrate (rAT-gamma) is titrated according to patient body weight (BW), while conventional plasma-derived antithrombin concentrates (AT) are administered as a fixed dose.
Hiromitsu Kuroda MD   +1 more
doaj   +1 more source

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