Results 71 to 80 of about 22,631 (237)

The Association between the Level of Antithrombin III and Mortality in Children with Sepsis

, 2019
BACKGROUND: Sepsis is a significant cause of morbidity and mortality in children. The diagnosis of sepsis remains continuing to develop which determines treatment and prognostic.
Lubis, Munar, Lestari, Indah Nur, Yoel, Chairul   +2 more
core   +1 more source

Gene Editing for Haemophilia—The Next Frontier

Haemophilia, EarlyView.
ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti, Gregory A. Newby, Sundar Selvaraj, Steven W. Pipe   +3 more
wiley   +1 more source

Antithrombin III Alleviates Myocardial Ischemia/Reperfusion Injury by Inhibiting Excessive Autophagy in a Phosphoinositide 3-Kinase/Akt-Dependent Manner

Frontiers in Pharmacology, 2019
Autophagy is fundamental to myocardial ischemia/reperfusion (I/R) injury. Antithrombin III (AT) has been shown to protect cardiomyocytes against I/R injury; however, it is unknown whether it modulates autophagy.
Kai-yu Huang, Jiao-ni Wang, Ying-ying Zhou, Shao-ze Wu, Shao-ze Wu, Lu-yuan Tao, Lu-yuan Tao, Yang-pei Peng, Jia-qun Que, Yang-jing Xue, Kang-ting Ji   +10 more
doaj   +1 more source

Impact of Treatment Response to Anticoagulant Therapy on Liver‐Related Events in Patients With Cirrhosis and Portal Vein Thrombosis

Hepatology Research, EarlyView.
In patients with cirrhosis and a first portal vein thrombosis treated with intravenous anticoagulant therapy, the 3‐year cumulative rates of liver‐related events were 56.7% and 75.5% in the effective and ineffective groups, respectively. A good radiological response was associated with fewer liver‐related hospitalizations.
Atsushi Maeda, Yuki Tahata, Hayato Hikita, Hisashi Ishida, Takayuki Yakushijin, Masanori Nakahara, Kazuyoshi Ohkawa, Fumihiko Nakanishi, Sadaharu Iio, Ryotaro Sakamori, Mitsuru Sakakibara, Masanori Miyazaki, Yuta Myoin, Kazuki Maesaka, Kumiko Shirai, Kazuhiro Murai, Yuki Makino, Yoshinobu Saito, Takahiro Kodama, Tetsuo Takehara   +19 more
wiley   +1 more source

Haemostatic disorders in nonsplenectomized and splenectomized thalassaemic children

, 1999
1171-1177A group of 40 thalassaemic patients [20 splenectomized and 20 nonsplenectomized] from the Haematology Unit of Tanta University Hospital [age range: 3-14 years] were studied to identify the mechanisms by which haemorrhagic and thrombotic ...
El Sharkawy, H.M., El Fadaly, N.H., Shebl, S.   +2 more
core  

Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications

Journal of Periodontal Research, EarlyView.
Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu, Yuan Chen, Mario Romandini, Håvard Jostein Haugen, Sašo Ivanovski   +4 more
wiley   +1 more source

Influence of transgenic recombinant Antithrombin-III compared with human Antithrombin-III in heparinresistent patients

, 2007
Diese Studie untersucht die Wirkung von genetisch rekombinantem Antithrombin-III im Vergleich zu humanen Plasma-Antithrombin-III bei heparinresistenten Patienten, die sich einer elektiver aortocoronarer Bypass-Operation unter Einsatz einer Herz-Lungen ...
Dube, Daniela
core  

Antithrombin activity of fucoidan. The interaction of fucoidan with heparin cofactor II, antithrombin III, and thrombin

, 1989
Fucoidan, poly(L-fucopyranose) linked primarily alpha 1----2 with either a C3- or a C4-sulfate, is an effective anticoagulant in vitro and in vivo (Springer, G. F., Wurzel, H. A., McNeal, G. M., Jr., Ansell, N. J., and Doughty, M. F. (1957) Proc.
Meade, J B, Church, F C, Treanor, R E, Whinna, H C   +3 more
core   +1 more source

Transfusion of blood products to neonatal and pediatric extracorporeal membrane oxygenation patients: A prospective, observational study

Transfusion, EarlyView.
Abstract Study Question To describe the blood product utilization during neonatal and pediatric extracorporeal membrane oxygenation (ECMO) and to determine whether its usage correlates with clinical outcomes of bleeding, thrombosis or mortality. Design Prospective observational study of neonatal and pediatric ECMO patients from September 2016, until ...
Rebecca Barton, Suelyn Van Den Helm, Hui Ping Yaw, Chantal Attard, Graeme MacLaren, Vera Ignjatovic, Natasha Letunica, Vasiliki Karlaftis, Tengyi Cai, Amy Johansen, Derek Best, Roberto Chiletti, Yves d'Udekem, Jo McKittrick, Warwick Butt, Paul Monagle   +15 more
wiley   +1 more source

Prevalence of Inherited Thrombophilia in Women with Recurrent Pregnancy Loss During the First Trimester of Pregnancy

Journal of Blood Medicine, 2023
Tagwa Yousif Elsayed Yousif1,2 1Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Gizan, 45142, Saudi Arabia; 2Department of Medical Laboratory Sciences, College of Medical Laboratory Sciences, Alneelian ...
Yousif TYE
doaj