Results 61 to 70 of about 37,867 (235)

Antithrombin III Alleviates Myocardial Ischemia/Reperfusion Injury by Inhibiting Excessive Autophagy in a Phosphoinositide 3-Kinase/Akt-Dependent Manner

Frontiers in Pharmacology, 2019
Autophagy is fundamental to myocardial ischemia/reperfusion (I/R) injury. Antithrombin III (AT) has been shown to protect cardiomyocytes against I/R injury; however, it is unknown whether it modulates autophagy.
Kai-yu Huang, Jiao-ni Wang, Ying-ying Zhou, Shao-ze Wu, Shao-ze Wu, Lu-yuan Tao, Lu-yuan Tao, Yang-pei Peng, Jia-qun Que, Yang-jing Xue, Kang-ting Ji   +10 more
doaj   +1 more source

Dried plasma retains hemostatic function and thermal stability during Arctic military operations

Transfusion, EarlyView.
Abstract Background Dried plasma offers a practical alternative for remote damage control resuscitation, providing hemostatic support and volume replacement. The Arctic presents challenges that necessitate the need for blood‐based resuscitation to extend the “golden hour.” To address this, we evaluated the hemostatic and thermal stability of dried ...
Kanwal Singh, Aron A. Shoara, Henry T. Peng, Viktor Prifti, Katy Moes, Cerys McGuinness, Tristan Bonnici, Maria Shiu, Sushmaa Chandralekha Selvakumar, Peter Andrisani, Pierre‐Marc Dion, Damien Miller, Sebastian Vuong, Colin A. Kretz, Philip J. Wallace, Shawn G. Rhind, Wendy Sullivan‐Kwantes, Andrew N. Beckett   +17 more
wiley   +1 more source

[Antithrombin III].

Annales de biologie clinique, 1987
The in vivo regulation of coagulation is mainly controlled by plasma inhibitors in which antithrombin III (AT III) plays an importance role. AT III is a glycoprotein which inhibits all serine proteases, except factor, VIIa, generated during the coagulation process. The proteases are inactivated by formation of an equimolecular complex and this reaction
C, Boyer-Neumann, M, Wolf, M J, Larrieu
openaire   +3 more sources

Estrogen as a therapeutic agent: Targeting endotheliopathy and coagulopathy in trauma

Transfusion, EarlyView.
Abstract Background Traumatic injury remains a leading cause of death, often due to uncontrolled hemorrhage and trauma‐induced coagulopathy (TIC). TIC is critically triggered by the endotheliopathy of trauma, involving endothelial cell injury and glycocalyx degradation. Despite conventional advances, the stable casualty rate underscores the urgent need
Niruktha Raghavan, Mira Patel, Bryan A. Cotton, Julia Coleman, Donald Jenkins   +4 more
wiley   +1 more source

An assessment of green plasma: The in vitro hemostatic superiority of a currently discarded blood product

Transfusion, EarlyView.
Abstract Introduction Recent studies have linked trauma patient outcomes to the plasma donor's sex, with premenopausal females associated with improved survival and lower organ failure. Currently, green‐colored plasma (due to oral contraceptive use) is removed from the donor pool. We set out to evaluate the hemostatic potential of green plasma.
Samantha C. Redden, David J. Sun, Yao‐Wei W. Wang, Elizabeth Hartwell, Jessica C. Cardenas, Scott D. Olson, Bryan A. Cotton   +6 more
wiley   +1 more source

Use of recombinant human antithrombin concentrate in pregnancy

International Journal of Women's Health, 2013
Lisa M Baumann Kreuziger,1 Tracy L Prosen,2 Mark T Reding1 1Division of Hematology, Oncology, and Transplantation, University of Minnesota, MN, USA; 2Obstetrics and Gynecology, Maternal Fetal Medicine Center, University of Minnesota, MN, USAWe read with ...
Baumann Kreuziger LM, Prosen TL, Reding MT   +2 more
doaj  

Prevalence of Inherited Thrombophilia in Women with Recurrent Pregnancy Loss During the First Trimester of Pregnancy

Journal of Blood Medicine, 2023
Tagwa Yousif Elsayed Yousif1,2 1Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Gizan, 45142, Saudi Arabia; 2Department of Medical Laboratory Sciences, College of Medical Laboratory Sciences, Alneelian ...
Yousif TYE
doaj  

Declaring futility after traumatic injury and the burden of failure on the surgeon

Transfusion, EarlyView.
Abstract In this edition of the THOR supplement in Transfusion, there are two articles that deal with resuscitation futility and transfusion. In one article, Yazer et al. delve into the details of the studies outlined in this editorial and summarize the literature on the topic of transfusion and futility. The second article by Dr.
Jan‐Michael Van Gent, Bryan A. Cotton
wiley   +1 more source

Initial Presentation of HIV Infection With Two Successive Acute Arterial Thromboses: A Case Report. [PDF]

, 2014
IntroductionOne of the complications of HIV infection is greater risk of thromboembolic events. A variety of mechanisms has been found to be responsible for prothrombotic tendency in patients with HIV infection.Case presentationA 27-year-old heterosexual
Moslemi, Sam, Tahamtan, Maryam, Ziaian, Bizhan   +2 more
core   +1 more source

Evaluation of the level of antithrombin in patients with glomerulonephritis and nephrotic syndrome: A cross-sectional study

Український Журнал Нефрології та Діалізу
The present study aimed to evaluate the level of antithrombin (AT)-III in blood serum in patients with primary glomerulonephritis (GN) and nephrotic syndrome (NS) and to assess its correlation with markers of NS and hypercoagulation. Methods.
I. Mykhaloiko, R. Yatsyshyn, I. Dudar, H. Kuryliv   +3 more
doaj   +1 more source