Results 31 to 40 of about 49,507 (253)

Fetal loss in women with hereditary thrombophilic defects and concomitance of other thrombophilic defects:a retrospective family study [PDF]

, 2012
Objective To assess the absolute risk of fetal loss associated with hereditary deficiencies of antithrombin (AT), protein C (PC) and protein S (PS), and the contribution of additional thrombophilic defects to this risk.
Brouwer, J-L P., Erwich, J. J. H. M., Folkeringa, N., Holm, J. P., Korteweg, F. J., van der Meer, J., Veeger, N. J. G. M.   +6 more
core   +5 more sources

Supplementation therapy with Antithrombin Drugs in the Combined Treatment of Sepsis

Общая реаниматология, 2019
Purpose — to assess the efficacy of supplementation therapy for antithrombin deficiency in the combined treatment of sepsis.Materials and methods. A prospective-retrospective study of the efficacy of supplementation therapy for antithrombin deficiency ...
I. V. Redkin, A. F. Lopatin, A. G. Yavorovskiy, V. V. Likhvantsev   +3 more
doaj   +1 more source

An antibody that prevents serpin polymerisation acts by inducing a novel allosteric behavior [PDF]

, 2016
Serpins are important regulators of proteolytic pathways with an antiprotease activity that involves a conformational transition from a metastable to a hyperstable state. Certain mutations permit the transition to occur in the absence of a protease; when
Faull, Sarah V., Haq, Imran, Heyer Chauhan, Narinder, Irving, James A., Jagger, Alistair M., Kay, Christopher W. M., Liedtke, Maximilian, Lomas, David A., MIRANDA BANOS, MARIA ELENA, Motamedi Shad, Neda, Nanda, Arjun Scott, Ordóñez, Adriana, Perez, Juan, Salvadori, Enrico, Wort, Joshua L.   +14 more
core   +1 more source

Correction of Antithrombin III Deficiency in Disseminated Intravascular Coagulation

Общая реаниматология, 2008
Although antithrombin (AT) III concentrate therapy is attended by an increased risk of hemorrhage, the data available in the literature suggest that the agent may have a positive effect on outcome in disseminated intravascular coagulation (DIC ...
Ye. L. Neporada, N. A. Vorobyeva, E. V. Nedashkovsky   +2 more
doaj   +1 more source

Prevalence of thrombophilia in indian patients with deep venous thrombosis – An 8-year single-center study

Indian Journal of Vascular and Endovascular Surgery, 2022
Background: Thrombophilia is a recognized risk factor for deep venous thrombosis (DVT) and its recurrence. Routine thrombophilia testing is controversial because of low yield and high cost.
Vivek Agrawal, Sanjeev Kumar Deshpande, Brijesh Biswas, Suresh Reddy Thupakula, Vembu Anand   +4 more
doaj   +1 more source

Antithrombin Debrecen (p.Leu205Pro) - Clinical and molecular characterization of a novel mutation associated with severe thrombotic tendency [PDF]

, 2017
K
Bereczky, Zsuzsanna, Boda, Zoltán, Bárdos, Helga, Fekete, Attila, Gindele, Réka, Ilonczai, Péter, Komáromi, István, Kovács, Kitti Bernadett, Molnárné Rázsó, Katalin, Muszbek, László, Oláh, Zsolt, Schlammadinger, Ágota, Selmeczi, Anna, Ádány, Róza   +13 more
core   +1 more source

Frequency of Protein C, S and Antithrombin III Deficiency and Presence of Antibodies of Antiphospholipid Syndrome in Women with Recurrent Abortion [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2019
Introduction: Recurrent abortion is defined as three or more spontaneous miscarriages before first trimester of pregnancy. Protein C, S, Antithrombin III deficiency is of the min factors of this disease.
Mohammad Matin, Davoud Bashash, Kambiz Hasrak, Ahmadreza Baghestani, Mohsen Hamidpour   +4 more
doaj   +1 more source

Antithrombin III Deficiency in Indian Patients with Deep Vein Thrombosis: Identification of First India Based AT Variants Including a Novel Point Mutation (T280A) that Leads to Aggregation

PLoS ONE, 2015
Antithrombin III (AT) is the main inhibitor of blood coagulation proteases like thrombin and factor Xa. In this study we report the identification and characterization of several variants of AT for the first time in Indian population.
Teena Bhakuni, Amit Sharma, Qudsia Rashid, Charu Kapil, R. Saxena, M. Mahapatra, M. A. Jairajpuri   +6 more
semanticscholar   +1 more source

Comparison of Protective Effects of Recombinant Antithrombin Gamma and Plasma-Derived Antithrombin on Sepsis-Induced Disseminated Intravascular Coagulation and Multiple Organ Failure

Clinical and Applied Thrombosis/Hemostasis, 2020
In Japan, the dose of the new recombinant antithrombin III concentrate (rAT-gamma) is titrated according to patient body weight (BW), while conventional plasma-derived antithrombin concentrates (AT) are administered as a fixed dose.
Hiromitsu Kuroda MD, Yoshiki Masuda MD, PhD   +1 more
doaj   +1 more source

Hemostatic system changes predictive value in patients with ischemic brain disorders [PDF]

Vojnosanitetski Pregled, 2002
The aim of this research was to determine the importance of tracking the dynamics of changes of the hemostatic system factors (aggregation of thrombocytes, D-dimer, PAI-1, antithrombin III, protein C and protein S, factor VII and factor VIII, fibrin ...
Raičević Ranko, Jovičić Aco, Mandić-Radić Slavka, Đorđević Dragana, Magdić Bratislav, Marković Ljubo, Veljančić Dragana, Dinčić Evica, Obradović Slobodan   +8 more
doaj   +1 more source