The impact of antithrombin III supplementation on prognosis during extracorporeal membrane oxygenation: a systematic review and meta-analysis. [PDF]
Zeng YT +4 more
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BMI differences on anticoagulation with bivalirudin vs. heparin during primary PCI: a BRIGHT-4 subanalysis. [PDF]
Zhang D +22 more
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A single-dose, four-cycle, fully repetitive crossover bioequivalence of dabigatran etexilate in Chinese. [PDF]
Yang Z +17 more
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The efficacy and safety of bivalirudin and heparin in patients with acute coronary syndrome: a systematic review and meta-analysis. [PDF]
Zhai Y +5 more
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Prior Anticoagulation and Risk of Hemorrhagic Transformation in Acute Stroke: A Post Hoc Analysis of the PRODAST Study. [PDF]
Grosse GM +13 more
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Dabigatran Attenuates the Binding of Thrombin to Platelets-A Novel Mechanism of Action. [PDF]
Lindahl TL +7 more
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Importance of infarct topography in determination of stroke mechanism and recurrence risk: a post-hoc analysis of the dabigatran acute treatment of stroke trial. [PDF]
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Antithrombin (AT) is a heparin cofactor and a member of the serine protease inhibitor family (serpin). The mature AT molecule is composed of 432 amino acids and it is produced mainly in the liver. Initially, several different AT activities in plasma were reported, leading to the classification of antithrombin in a range from I to IV.
Mirta, Hepner, Vasiliki, Karlaftis
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Angiogenesis is critical for several physiologic and pathophysiologic processes, and several angiogenesis inhibitors are now in clinical trials for the treatment of cancer. Antithrombin is a member of the serpin family of proteins and functions as an inhibitor of thrombin and other enzymes involved in the clotting cascade. While studying the inhibition
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