Results 11 to 20 of about 1,433 (211)

Insight into Residues Critical for Antithrombin Function from an Expanded Database of Sequences That Includes Frog, Turtle and Ostrich Antithrombins

The Scientific World Journal, 2002
Marija Backovic, Peter G.W. Gettins
doaj   +3 more sources

The Influence of Calcium on the Binding of Antithrombin by Antithrombin Inhibitor.

Experimental Biology and Medicine, 1966
Summary and Conclusions1. The reaction between antithrombin and inhibitor has a quantitative requirement for calcium. 2. Calcium is not the inhibitor of antithrombin. 3. Calcium is not required for neutralization of thrombin by antithrombin.
H H, Henstell, M, Kligerman
openaire   +2 more sources

A test for antithrombin in the blood [PDF]

Experimental Biology and Medicine, 1914
A test is described for the estimation of antithrombin in the blood. The chief advantage of the test is that it is simple, and does not require the preparation of fibrinogen and of thrombin, which are difficult to prepare and to maintain in a pure state.
openaire   +2 more sources

O novo modelo da cascata de coagulação baseado nas superfícies celulares e suas implicações A cell-based model of coagulation and its implications

Revista Brasileira de Hematologia e Hemoterapia, 2010
O conceito da cascata da coagulação descreve as interações bioquímicas dos fatores da coagulação, entretanto, tem falhado como um modelo do processo hemostático in vivo. A hemostasia requer a formação de um tampão de plaquetas e fibrina no local da lesão
Cláudia Natália Ferreira, Marinez de Oliveira Sousa, Luci Maria Sant'Ana Dusse, Maria das Graças Carvalho   +3 more
doaj   +1 more source

Use of Antithrombin and Thrombomodulin in the Management of Disseminated Intravascular Coagulation in Patients with Acute Cholangitis

Gut and Liver, 2013
Background/AimsTo evaluate the usefulness and safety of treating disseminated intravascular coagulation (DIC) complicating cholangitis primarily with antithrombin (AT) and thrombomodulin (rTM).Methods : A DIC treatment algorithm was determined on the ...
doaj   +1 more source

Insight into Residues Critical for Antithrombin Function from Analysis of an Expanded Database of Sequences That Includes Frog, Turtle, and Ostrich Antithrombins

, 2016
Complete sequences were determined for frog, turtle, and ostrich antithrombins. Protein sequence comparisons with the other 10 known antithrombin sequences and with sequences of other serpins have provided striking evidence for the conservation of the ...
Peter G. W. Gettins (3087792), Marija Backovic (3087789)   +1 more
core   +1 more source

Efficacy and safety of direct oral anticoagulants compared with warfarin in antiphospholipid syndrome. Results of a multicenter retrospective cohort study

Research and Practice in Thrombosis and Haemostasis
Background: Direct oral anticoagulants (DOACs) have become firstline treatment for many thrombotic conditions, but their use in antiphospholipid syndrome (APS) patients remains controversial.
Maha A.T. Elsebaie, Zoe Wickham, Stephanie DeBragga, Stacey Fedewa, Mohamed Amgad, Jane Jungyoon Park, Allen Li, Ali Eshaghpour, Juan Li, Mark Crowther, Manila Gaddh   +10 more
doaj   +1 more source

Thrombin-Fibrin(ogen) Interactions, Host Defense and Risk of Thrombosis

, 2021
Fibrinogen is a well-known risk factor for arterial and venous thrombosis. Its function is not restricted to clot formation, however, as it partakes in a complex interplay between thrombin, soluble plasma fibrinogen, and deposited fibrin matrices ...
Hemker, H Coenraad, Henri M. H. Spronk, Hulshof, Anne-Marije, Spronk, Henri M H, Hugo ten Cate, Anne-Marije Hulshof, Yvonne M. C. Henskens, Ten Cate, Hugo, Henskens, Yvonne M C, H. Coenraad Hemker   +9 more
core   +1 more source

Antiangiogenic antithrombin down-regulates the expression of the proangiogenic heparan sulfate proteoglycan, perlecan, in endothelial cells

, 2010
[[abstract]]Antithrombin, a key serpin family regulator of blood coagulation proteases, is transformed into a potent antiangiogenic factor by limited proteolysis or mild heating.
Zhang, WQ;Chuang, YJ;Swanson, R;Li, J;Seo, KG;Leung, L;Lau, LF;Olson, ST
core   +1 more source

Assessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli, Cecilia Nalli, Francesca Crisafulli, Carlo Garaffoni, Marcello Govoni, Giulia Voltarel, Alba C. Pozzi, Beatrice Maranini, Ettore Silvagni, Alessandra Bortoluzzi, Angela Tincani   +10 more
wiley   +1 more source