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Small but Steady Steps in Stroke Medicine in Japan
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Kazunori Toyoda +2 more
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Orai1: a channel to safer antithrombotic therapy
, 2009 In this issue of Blood, Braun and colleagues identify Orai1 as the major component of the store-operated Ca2+ entry channel in platelets.
Authi, Kalwant S.
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Antithrombotics: backgrounds with haemostasis and antithrombotic therapy
Nederlands Tijdschrift voor Tandheelkunde, 2020The clinical guidelines on antithrombotics, published by the Dutch Institute of Expertise for Oral Healthcare, give advice on policy to be followed in cases of dental procedures involving bleeding. The guidelines allow room for professional assessment of bleeding risks, for which background knowledge about haemostasis, thrombosis and antithrombotic ...
B, van Minnen +4 more
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Seminars in Thrombosis and Hemostasis, 1998
From injury through healing, thrombin has several important functions in blood clotting, subsequent clot lysis, and tissue repair. These include edema, inflammation, cell recruitment, cellular releases, transformations, mitogenesis, and angiogenesis. Thrombin also participates in disease states, such as venous thrombosis, coronary thrombosis, stroke ...
J W, Fenton +3 more
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From injury through healing, thrombin has several important functions in blood clotting, subsequent clot lysis, and tissue repair. These include edema, inflammation, cell recruitment, cellular releases, transformations, mitogenesis, and angiogenesis. Thrombin also participates in disease states, such as venous thrombosis, coronary thrombosis, stroke ...
J W, Fenton +3 more
openaire +2 more sources
Topics in Companion Animal Medicine, 2012
Thrombosis or thromboembolism are significant concerns in companion animals and can be associated with cardiac, metabolic, neoplastic disease processes or can be one manifestation of inflammatory, infectious, and neoplastic disease conditions. Options for thromboprophylaxis available for clinical use in small animal patients are very limited, with ...
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Thrombosis or thromboembolism are significant concerns in companion animals and can be associated with cardiac, metabolic, neoplastic disease processes or can be one manifestation of inflammatory, infectious, and neoplastic disease conditions. Options for thromboprophylaxis available for clinical use in small animal patients are very limited, with ...
openaire +2 more sources
2016
Symptomatic cerebral atherosclerosis including intracranial atherosclerosis (ICAS) is associated with a high risk of recurrent stroke. Antithrombotic agents are the mainstay of therapy in these patients. Several studies have found anticoagulation (warfarin) to increase the risk of bleeding events and have an efficacy no better than that of aspirin ...
Sun U, Kwon, Jong S, Kim
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Symptomatic cerebral atherosclerosis including intracranial atherosclerosis (ICAS) is associated with a high risk of recurrent stroke. Antithrombotic agents are the mainstay of therapy in these patients. Several studies have found anticoagulation (warfarin) to increase the risk of bleeding events and have an efficacy no better than that of aspirin ...
Sun U, Kwon, Jong S, Kim
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Future Cardiology, 2007
Karjalainen PP, Porela P, Ylitalo A et al.: Safety and efficacy of combined antiplatelet-warfarin therapy after coronary stenting. Eur. Heart J. 28(6), 726-732 (2007). Chronic oral antithrombotic treatment is necessary in patients with mechanical heart valves and in the majority of patients with atrial fibrillation.
Willem, Dewilde, J M, ten Berg
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Karjalainen PP, Porela P, Ylitalo A et al.: Safety and efficacy of combined antiplatelet-warfarin therapy after coronary stenting. Eur. Heart J. 28(6), 726-732 (2007). Chronic oral antithrombotic treatment is necessary in patients with mechanical heart valves and in the majority of patients with atrial fibrillation.
Willem, Dewilde, J M, ten Berg
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Chest, 1998
The development of new antithrombotic agents has been stimulated by clinical needs and by advances in biotechnology that have made it possible to produce drugs that target specific steps in thrombogenesis. Heparin has pharmacokinetic and biophysical limitations that are overcome by new anticoagulants.
J I, Weitz, J, Hirsh
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The development of new antithrombotic agents has been stimulated by clinical needs and by advances in biotechnology that have made it possible to produce drugs that target specific steps in thrombogenesis. Heparin has pharmacokinetic and biophysical limitations that are overcome by new anticoagulants.
J I, Weitz, J, Hirsh
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Antithrombotic Reversal Agents
Hematology/Oncology Clinics of North America, 2014The actively bleeding anticoagulated patient presenting to the emergency department requires rapid evaluation and treatment, which is made increasingly complicated by the ever-evolving antithrombotic treatment options used in medicine. Even with excellent supportive care, the timeliness with which reversal decisions need to be made continues to demand ...
Matthew D, Wilson, Jonathan E, Davis
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2022
Abstract There are many reasons to consider treating patients with heart failure with antithrombotic agents, including atrial fibrillation, coronary artery disease (CAD), intracardiac thrombus, prevention and treatment of deep vein thrombosis, and to reduce thrombotic complications of left ventricular assist devices or mechanical valves.
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Abstract There are many reasons to consider treating patients with heart failure with antithrombotic agents, including atrial fibrillation, coronary artery disease (CAD), intracardiac thrombus, prevention and treatment of deep vein thrombosis, and to reduce thrombotic complications of left ventricular assist devices or mechanical valves.
openaire +1 more source