Results 11 to 20 of about 23,898 (157)

Antithrombotic alternatives for stroke prevention in atrial fibrillation: critical differences and remaining questions

open access: yesDrugs in Context, 2013
Three therapeutic alternatives for prevention of stroke in patients with atrial fibrillation are available in dabigatran (an oral direct thrombin inhibitor), rivaroxaban, and apixaban (both oral blood coagulation factor Xa inhibitors).
James S Kalus
doaj   +2 more sources

Antithrombotic Management in AF Patients Following Percutaneous Coronary Intervention: A European Perspective [PDF]

open access: yes, 2023
AF is a highly prevalent disease, often requiring long-term oral anticoagulation to prevent stroke or systemic embolism. Coronary artery disease, which is common among AF patients, is often referred for myocardial revascularisation by percutaneous ...
Antonio Greco   +3 more
core   +1 more source

Marine Antithrombotics [PDF]

open access: yesMarine Drugs, 2020
Thrombosis remains a prime reason of mortality worldwide. With the available antithrombotic drugs, bleeding remains the major downside of current treatments. This raises a clinical concern for all patients undergoing antithrombotic therapy. Novel antithrombotics from marine sources offer a promising therapeutic alternative to this pathology.
Rohini Dwivedi, Vitor H. Pomin
openaire   +3 more sources

Antithrombotic dilemmas in stroke medicine: new data, unsolved challenges [PDF]

open access: yes, 2022
Antithrombotic therapy is a key element of secondary prevention in patients who have had an ischaemic stroke or transient ischaemic attack. However, its use in clinical practice is not always straightforward.
Seiffge, David J   +19 more
core   +2 more sources

Antithrombotics today [PDF]

open access: yesVnitřní lékařství, 2018
Over the last 10 years some new drugs affecting blood clotting - antithrombotics - were invented. For more than half a century only warfarin and heparin were available. A better understanding of the pathways involved in activation of blood clotting, the links between these systems, and the impact of thrombosis on inflammation, have led to ...
Miloslava, Matýšková   +2 more
openaire   +2 more sources

Multidisciplinary approach to safety of antithrombotic therapy: focus on the gastrointestinal tract

open access: yes, 2021
Multidisciplinary approach to safety of antithrombotic therapy used in clinical practice is reported. Such complications of antithrombotic therapy as gastrointestinal tract (GIT) erosion/ulceration and gastrointestinal bleeding are discussed in detail ...
Marina V. Buyanova   +2 more
core   +1 more source

P2Y12 Receptor Function and Response to Cangrelor in Neonates With Cyanotic Congenital Heart Disease

open access: yesJACC: Basic to Translational Science, 2017
Shunt thrombosis remains a major cause of morbidity and mortality, especially during the initial palliation for single-ventricle physiology. The authors present evidence that the P2Y12 inhibitor cangrelor may fill a therapeutic void in thromboprophylaxis.
Elisabeth A. Kaza, MD   +10 more
doaj   +1 more source

Antithrombotic/Antiplatelet Treatment in Transcatheter Structural Cardiac Interventions—PFO/ASD/LAA Occluder and Interatrial Shunt Devices

open access: yesFrontiers in Cardiovascular Medicine, 2019
Transcatheter interventions enable safe and efficient treatment of various structural heart diseases. However, therapy does not finished with the end of the procedure. Device thrombosis is a possible serious complication.
Anna Olasinska-Wisniewska, Marek Grygier
doaj   +1 more source

Saponins: Research Progress and Their Potential Role in the Post-COVID-19 Pandemic Era

open access: yesPharmaceutics, 2023
In the post-COVID-19 pandemic era, the new global situation and the limited therapeutic management of the disease make it necessary to take urgent measures in more effective therapies and drug development in order to counteract the negative global ...
Daniel Mieres-Castro   +1 more
doaj   +1 more source

New Prospective for the Management of Low-Risk Pulmonary Embolism: Prognostic Assessment, Early Discharge, and Single-Drug Therapy with New Oral Anticoagulants

open access: yesScientifica, 2012
Patients with pulmonary embolism (PE) can be stratified into two different prognostic categories, based on the presence or absence of shock or sustained arterial hypotension.
Alessandro Squizzato
doaj   +1 more source

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