Results 131 to 140 of about 3,970 (174)
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Archives of Dermatology and Syphilology, 1948
Recently certain synthetic materials have been found that oppose the formation of thyroxin, the active principle of the thyroid gland. This newer group consists of a number of substances, of which thiouracil and propylthiouracil have become the best known.
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Recently certain synthetic materials have been found that oppose the formation of thyroxin, the active principle of the thyroid gland. This newer group consists of a number of substances, of which thiouracil and propylthiouracil have become the best known.
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Endocrinology, 1965
Several congeners of salicylate, previously shown to inhibit the binding of thyroxine in serum and to alter its peripheral metabolism in man, have been found to inhibit thyroid hormone synthesis. The most potent were 2,3-dihydroxybenzoic acid, 3,5- dihydroxybenzoic acid, 2,4-dihydroxybenzoic (beta-resorcylic) acid, and 2,6-dihydroxybenzoic (gamma ...
K A, WOEBER, S H, INGBAR
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Several congeners of salicylate, previously shown to inhibit the binding of thyroxine in serum and to alter its peripheral metabolism in man, have been found to inhibit thyroid hormone synthesis. The most potent were 2,3-dihydroxybenzoic acid, 3,5- dihydroxybenzoic acid, 2,4-dihydroxybenzoic (beta-resorcylic) acid, and 2,6-dihydroxybenzoic (gamma ...
K A, WOEBER, S H, INGBAR
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Recurrent agranulocytosis induced by two different antithyroid agents
Medical Journal of Australia, 1983A 45-year-old woman with thyrotoxicosis developed agranulocytosis after treatment with propylthiouracil. When the thyrotoxicosis recurred, accompanied by a severe psychotic reaction, administration of antithyroid medication was recommenced. The patient was given methimazole instead of propylthiouracil but, 10 weeks later, agranulocytosis again occurred.
B, Chen, R, Lang, Y, Jutrin, M, Ravid
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[Fever due to antithyroid agents].
Nederlands tijdschrift voor geneeskunde, 1999Three patients, females aged 62, 67 and 32 years, were presented with fever and sore throat and had severe agranulocytosis (granulocyte count < 100/microliter). All had Graves' disease and were being treated with thiamazole 30 mg once a day. Thiamazole was discontinued and treatment with antibiotics initiated.
S O, Shamelian, J W, Nortier
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Acta Endocrinologica, 1992
We studied the antithyroid action of cigarette smoking products (nicotine, cotinine, and thiocyanate) in the physiological culture system of porcine thyroid follicles. Iodide uptake, iodine organification, de novo thyroid hormone formation, and iodide efflux were measured in the presence of 0–200 μmol/l nicotine, cotinine, or potassium thiocyanate ...
H, Fukayama +3 more
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We studied the antithyroid action of cigarette smoking products (nicotine, cotinine, and thiocyanate) in the physiological culture system of porcine thyroid follicles. Iodide uptake, iodine organification, de novo thyroid hormone formation, and iodide efflux were measured in the presence of 0–200 μmol/l nicotine, cotinine, or potassium thiocyanate ...
H, Fukayama +3 more
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[Antithyroid agents and embryopathies].
Annales d'endocrinologie, 2004First cause of hyperthyroidism among women of childbearing age, Graves' disease raises the risk of maternal and fetal complications, including eclampsia, cardiac failure, abortion, prematurity, fetal death, all of which can be avoided if maternal hyperthyroidism is closely controlled.
Cl, Bournaud, J, Orgiazzi
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Beta blocking agents and antithyroid drugs as adjuncts to radioiodine therapy
Seminars in Nuclear Medicine, 1971Since the major beneficial effects of 131 I therapy are often delayed for 3 to 5 mo or even longer, it is essential to provide more rapid control of thyrotoxic manifestations, particularly in severely ill patients or in those with complications, such as heart failure or psychosis.
K, Sterling, R, Hoffenberg
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131I treatment of diffuse and nodular toxic goitre with or without antithyroid agents
Acta Endocrinologica, 1982Abstract. The results of 131I treatment in combination with pre- and post-treatment with carbimazole (n = 122) were compared to the results of 131I used as the only antithyroid treatment (n = 203). The two groups of patients were fully comparable in regard to age, size of goitre and time of observation, and the same diagnostic criteria and dosage ...
H, Bliddal +5 more
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[Antithyroid agents related agranulocytosis: Literature review].
La Revue de medecine interne, 2017The antithyroid agents (carbimazole, methimazole, thiamazole, propylthiouracil and benzylthiouracile) are the drug class that is associated with a high risk of agranulocytosis. Acute and profound (
E, Andrès +7 more
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