Results 31 to 40 of about 47,153 (259)

Large-scale Purification of Type III Toxin-antitoxin Ribonucleoprotein Complex and its Components from Escherichia coli for Biophysical Studies

open access: yesBio-Protocol, 2023
Toxin–antitoxin (TA) systems are widespread bacterial immune systems that confer protection against various environmental stresses. TA systems have been classified into eight types (I–VIII) based on the nature and mechanism of action of the antitoxin ...
Parthasarathy Manikandan   +2 more
doaj   +1 more source

Antitoxin. [PDF]

open access: yesJournal of the American Medical Association, 1898
n ...
openaire   +2 more sources

Generation of Highly Efficient Equine-Derived Antibodies for Post-Exposure Treatment of Ricin Intoxications by Vaccination with Monomerized Ricin

open access: yesToxins, 2018
Ricin, a highly lethal toxin derived from the seeds of Ricinus communis (castor beans) is considered a potential biological threat agent due to its high availability, ease of production, and to the lack of any approved medical countermeasure against ...
Reut Falach   +11 more
doaj   +1 more source

Escherichia coli EHEC Germany outbreak preliminary functional annotation using BG7 system [PDF]

open access: yes, 2011
We have annotated the European outbreak E. coli EHEC genome sequenced by BGI (6-2-2011) and assembled with MIRA by Nick Loman (6-2-2011 ). Our system BG7, Bacterial Genome annotation of Era7 Bioinformatics, predicts ORFs and annotates them based on ...
Eduardo Pareja   +4 more
core   +2 more sources

Chaperone addiction of toxin–antitoxin systems

open access: yesNature Communications, 2016
Some bacterial toxin-antitoxin systems consist of a labile antitoxin that inhibits a toxin, and a chaperone that stabilizes the antitoxin. Here, Bordes et al.
Patricia Bordes   +8 more
doaj   +1 more source

An oxygen-sensitive toxin–antitoxin system

open access: yesNature Communications, 2016
Classical toxin–antitoxin systems in bacteria are based on silencing of a toxin by an antitoxin that, when inactivated, releases the toxin, resulting in a change in metabolism. Here, the authors characterize an oxygen-sensitive toxin–antitoxin system and
Oriol Marimon   +13 more
doaj   +1 more source

Postbooster Antibodies from Humans as Source of Diphtheria Antitoxin

open access: yesEmerging Infectious Diseases, 2016
Diphtheria antitoxin for therapeutic use is in limited supply. A potential source might be affinity-purified antibodies originally derived from plasma of adults who received a booster dose of a vaccine containing diphtheria toxoid. These antibodies might
Jesús F. Bermejo-Martin   +5 more
doaj   +1 more source

Toxin-Antitoxin Gene Pairs Found in Tn3 Family Transposons Appear To Be an Integral Part of the Transposition Module

open access: yesmBio, 2020
Much of the diversity of prokaryotic genomes is contributed by the tightly controlled recombination activity of transposons (Tns). The Tn3 family is arguably one of the most widespread transposon families.
Gipsi Lima-Mendez   +6 more
doaj   +1 more source

Immunological Characterization and Neutralizing Ability of Monoclonal Antibodies Directed Against Botulinum Neurotoxin Type H. [PDF]

open access: yes, 2016
BackgroundOnly Clostridium botulinum strain IBCA10-7060 produces the recently described novel botulinum neurotoxin type H (BoNT/H). BoNT/H (N-terminal two-thirds most homologous to BoNT/F and C-terminal one-third most homologous to BoNT/A) requires ...
Arnon, Stephen S   +5 more
core   +1 more source

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