Results 41 to 50 of about 59,908 (306)
mBio, 2020 Much of the diversity of prokaryotic genomes is contributed by the tightly controlled recombination activity of transposons (Tns). The Tn3 family is arguably one of the most widespread transposon families.
Gipsi Lima-Mendez +6 more
doaj +1 more source
A case of infant botulism in a 4-month-old baby [PDF]
, 2016 This case-report highlights: i) the difficulty of IB diagnosis as it is a rare syndrome with subclinical onset, ii) the need for an accurate training for physicians involved in IB management, iii) the efficacy and safety of TEqA in IB treatment, iv ...
Bruna Auricchio +6 more
core +1 more source
THE ANTITOXIN OF TETANUS. [PDF]
JAMA: The Journal of the American Medical Association, 1896 Among the many principles on which are based our modern theories of the etiology and therapeutics of disease is that of the vaccinating or immunizing power of attenuated cultures of specific microorganisms. Although this principle is forecast by Jenner's discovery of the vaccine against variola, it is to the great Frenchman, Pasteur, that should be ...
openaire +2 more sources
A widespread toxin−antitoxin system exploiting growth control via alarmone signaling
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance The alarmone (p)ppGpp is a central signaling nucleotide that is synthesized by RelA-SpoT Homologue (RSH) enzymes, and rewires bacterial physiology in response to stress. It is an unanswered question why bacteria often carry multiple (p)ppGpp-
Steffi Jimmy +13 more
semanticscholar +1 more source
Bio-Protocol, 2023 Toxin–antitoxin (TA) systems are widespread bacterial immune systems that confer protection against various environmental stresses. TA systems have been classified into eight types (I–VIII) based on the nature and mechanism of action of the antitoxin ...
Parthasarathy Manikandan +2 more
doaj +1 more source
Phage ϕC2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains [PDF]
, 2013 UNLABELLED: In this work, we show that Clostridium difficile phage ϕC2 transduces erm(B), which confers erythromycin resistance, from a donor to a recipient strain at a frequency of 10(-6) per PFU.
Chang, Barbara J +5 more
core +3 more sources
An oxygen-sensitive toxin–antitoxin system
Nature Communications, 2016 Classical toxin–antitoxin systems in bacteria are based on silencing of a toxin by an antitoxin that, when inactivated, releases the toxin, resulting in a change in metabolism. Here, the authors characterize an oxygen-sensitive toxin–antitoxin system and
Oriol Marimon +13 more
doaj +1 more source
Toxins, 2020 Botulinum neurotoxin serotype E (BoNT/E) is one of the major causes of human botulism, which is a life-threatening disease caused by flaccid paralysis of muscles. After receptor-mediated toxin internalization into motor neurons, the translocation domain (
Kwok-Ho Lam +3 more
doaj +1 more source
Small Open Reading Frames, Non-Coding RNAs and Repetitive Elements in Bradyrhizobium japonicum USDA 110 [PDF]
, 2016 Small open reading frames (sORFs) and genes for non-coding RNAs are poorly investigated components of most genomes. Our analysis of 1391 ORFs recently annotated in the soybean symbiont Bradyrhizobium japonicum USDA 110 revealed that 78% of them contain ...
Cuklina, Jelena +5 more
core +2 more sources