Results 71 to 80 of about 48,883 (257)

The vapB-vapC operon of Acidovorax citrulli functions as a bona-fide toxin-antitoxin module

open access: yesFrontiers in Microbiology, 2016
Toxin–antitoxin systems are commonly found on plasmids and chromosomes of bacteria and archaea. These systems appear as biscystronic genes encoding a stable toxin and a labile antitoxin, which protects the cells from the toxin’s activity. Under specific,
Reut eShavit   +4 more
doaj   +1 more source

Comparative Genomics of 9 Novel Paenibacillus Larvae Bacteriophages [PDF]

open access: yes, 2016
American Foulbrood Disease, caused by the bacterium Paenibacillus larvae, is one of the most destructive diseases of the honeybee, Apis mellifera. Our group recently published the sequences of 9 new phages with the ability to infect and lyse P.
Amy, Penny S.   +4 more
core   +2 more sources

Expanded Functional Characterization and Optimization of Protein Expression in Treponema denticola Shuttle Plasmids

open access: yesMolecular Oral Microbiology, EarlyView.
We report optimization of the Treponema denticola shuttle plasmid system by minimizing its size and by characterizing an array of promoter‐gene constructs for genetic complementation, including the first use in Treponema of a Tet‐inducible system for controlled expression of potentially toxic genes.
M. Paula Goetting‐Minesky   +8 more
wiley   +1 more source

The Sole Mycobacterium smegmatis MazF Toxin Targets tRNALys to Impart Highly Selective, Codon-Dependent Proteome Reprogramming

open access: yesFrontiers in Genetics, 2020
Survival of mycobacteria, both free-living and host-dependent pathogenic species, is dependent on their ability to evade being killed by the stresses they routinely encounter.
Valdir Cristovao Barth   +2 more
doaj   +1 more source

Force for ancient and recent life: viral and stem-loop RNA consortia promote life. [PDF]

open access: yes, 2014
Lytic viruses were thought to kill the most numerous host (i.e., kill the winner). But persisting viruses/defectives can also protect against viruses, especially in a ubiquitous virosphere. In 1991, Yarmolinsky et al.
Villarreal, Luis P
core   +1 more source

Viable but Nonculturable State, a Survival Strategy for Salmonella in Aquatic Environments

open access: yesWater and Environment Journal, EarlyView.
Transition of Salmonella from a culturable state to a viable but nonculturable state under various environmental stresses and current methods for detecting viable Salmonella in environmental samples. ABSTRACT In the relentless battle for survival, Salmonella has evolved mechanisms to withstand harsh conditions such as extreme temperatures, fluctuating ...
Sanelisiwe Thinasonke Duze   +3 more
wiley   +1 more source

Detoxification of Peptide-Containing Biotoxins

open access: yesВестник войск РХБ защиты
Highlights. Peptide biotoxins are important problem for human health and as lethal agents due to their wild diversity of chemical structures and biological sources.Such peptide biotoxins and prion proteins can be effectively neutralized by different ...
Ilya V. Lyagin   +4 more
doaj   +1 more source

Immunological Characterization and Neutralizing Ability of Monoclonal Antibodies Directed Against Botulinum Neurotoxin Type H. [PDF]

open access: yes, 2016
BackgroundOnly Clostridium botulinum strain IBCA10-7060 produces the recently described novel botulinum neurotoxin type H (BoNT/H). BoNT/H (N-terminal two-thirds most homologous to BoNT/F and C-terminal one-third most homologous to BoNT/A) requires ...
Arnon, Stephen S   +5 more
core   +1 more source

Protein design and RNA design: Perspectives

open access: yesQuantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Advances in deep learning and generative modeling have transformed the landscape of protein and RNA design, enabling rapid and precise creation of novel biomolecules with tailored structures and functions. In protein design, generative deep learning frameworks now support backbone generation, sequence optimization, and joint sequence–structure
Xi Chen, Xu Dai, Peilong Lu
wiley   +1 more source

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