Results 231 to 240 of about 545,238 (360)

Enhanced antitumor immunity of VNP20009-CCL2-CXCL9 via the cGAS/STING axis in osteosarcoma lung metastasis. [PDF]

J Immunother Cancer
Liu R, Liu Q, Wang Y, Liu T, Zhang Z, Zhao C, Tao H, Ogando-Rivas E, Castillo P, Zhang W.   +9 more
europepmc   +1 more source

Biological Studies on Peptimycin, a New Antitumor Antibiotic Produced by a Streptomyces.

, 1960
Tokuro HIKICHI
openalex   +2 more sources

Imiquimod‐Loaded Phospholipid‐Free Small Unilamellar Vesicles Activate the Tumor Immune Microenvironment to Treat Liver Cancer and Liver Metastases

Advanced Healthcare Materials, EarlyView.
Imiquimod‐loaded nanoparticles (PFSUV‐IMQ) are found to decrease liver metastasis and liver tumor burden when administered intravenously. Flow cytometry, RNA‐seq and various experiments show that the anti‐tumor response is immune‐mediated by activating dendritic cells resulting in increased CD8 T cell infiltration and activity.
Vanessa Chan, Hsin‐Mei Lee, Haruka Takata, Sheng‐Liang Cheng, Yu‐Ting Yen, Lisa Pfeifer, Luke Rushton, Po‐Han Chao, Feng Zhao, Chun Yat Ong, Nojoud Al‐Fayez, Tatsuhiro Ishida, Yunching Chen, Shyh‐Dar Li   +13 more
wiley   +1 more source

Oleic acid restores the impaired antitumor immunity of γδ-T cells induced by palmitic acid. [PDF]

Signal Transduct Target Ther
Zhang Y, Xiang Z, Xu Y, Cheung LS, Wang X, Wang M, Wong HHW, Zhu Z, Zhang W, Gao Y, Luo X, Cheuk YC, Zhou Y, Zha X, Chen Y, Li M, Luo F, Chu Y, Lau YL, Liu Y, Tu W.   +20 more
europepmc   +1 more source

Antitumor Effect of Mercury-Hematoporphyrin Complex on Solid-type Ehrlich Ascites Tumor Cells

, 1960
Mihoko Abe, Hideo Hirokawa, Yukito Masamune, Den’ichi Mizuno   +3 more
openalex   +2 more sources

cGAS is essential for the antitumor effect of immune checkpoint blockade

Proceedings of the National Academy of Sciences of the United States of America, 2017
Hua Wang, Shuiqing Hu, Xiang Chen, Heping Shi, Chuo Chen, Lijun Sun, Zhijian J. Chen   +6 more
semanticscholar   +1 more source

Tumor Microenvironment‐responsive Nanocatalyst for Targeted Chemodynamic Cancer Therapy

Advanced Healthcare Materials, EarlyView.
An Tumor microenvironment‐responsive nanocatalyst system composed of PLGA‐encapsulated Ca–Fe peroxide and polyarginine enables sustainable Fenton reaction in tumors. Low levels of H2O2 (50–100 µm) initiate the nanoparticle degradation, while polyarginine‐derived nitric oxide accelerates Fe3+ reduction, leading to self‐amplifying •OH generation for ...
Jun Ma, Jingjing Qiu, Shiren Wang
wiley   +1 more source

Review: radiotherapy-mediated B cells within the TLS influence the tumor microenvironment. [PDF]

J Immunother Cancer
Yang H, Chen K, Meng Y, Chen Z, Xu Y, Zhou D, Zhou S, Zhang X.   +7 more
europepmc   +1 more source

Synthetic Antitumor Agents

, 1962
Yoshio Sakurai
openalex   +2 more sources

A Targeted Redox‐Active Dual‐Action Pt(IV)‐Mn(II) Prodrug Displays Enhanced In Vivo Anticancer Activity

Advanced Healthcare Materials, EarlyView.
A new oxaliplatin‐based Pt(IV) prodrug bearing a Mn(II) superoxide dismutase mimic is synthesized and studied, in vitro and in vivo, in the context of colorectal cancer. Encapsulation of this prodrug in an easy‐to‐implement PEGylated micelle formulation demonstrated the highest in vivo anticancer activity among all the tested conditions, supporting the
Alvaro Lopez‐Sanchez, Henri Chédotal, Ram Pravin Kumar Muthuramalingam, Marine Thomas, Jia Ning Nicolette Yau, Priya Ranjan Sahoo, Clotilde Policar, Frédéric Batteux, Kadda Medjoubi, Andrea Somogyi, Giulia Adriani, Carole Nicco, Romain Coriat, Giorgia Pastorin, Hélène C. Bertrand   +14 more
wiley   +1 more source