Results 41 to 50 of about 491,510 (368)

mosmoon/extracellular-acidification-impairs-T-cell-infiltration-and-antitumor-activity: extracellular-acidification-impairs-T-cell-infiltration-and-antitumor-activity [PDF]

<p>extracellular-acidification-impairs-T-cell-infiltration-and-antitumor-activity</p ...
mosmoon
core   +1 more source

Antitumor activity and biodistribution of cisplatin nanocapsules in nude mice bearing human ovarian carcinoma xenografts [PDF]

, 2008
Cisplatin nanocapsules represent a novel lipid formulation of the anticancer drug cis-diamminedichloridoplatinum(II) (cisplatin), characterized by an unprecedented cisplatin-tolipid molar ratio, and exhibiting strongly increased in-vitro cytotoxicity ...
Biochemie van Membranen, Chemical Biology & Organic Chemistry, Hamelers, I.H., Membraan enzymologie, Erkelens, C.A.M., Erkelens, CA, Boven, E., Hamelers, I.H.L., van der Born, K., de Kroon, A.I.P.M., Peters, G.J., van der Born, K, Staffhorst, R.W.H.M., Staffhorst, R.W., Dep Scheikunde, de Kroon, A.I.   +15 more
core   +1 more source

Cytochalasin H enhances sensitivity to gefitinib in non-small-cell lung cancer cells through inhibiting EGFR activation and PD-L1 expression

Scientific Reports
In our previous study, we have isolated cytochalasin H (CyH) from endophytic fungus derived from mangrove plant and found that CyH inhibited the proliferation of non-small cell lung cancer (NSCLC) cells.
Guihong Zhang, Jiao Liu, Sanzhong Li, Tianyu Wang, Li Chen, Huan Li, Qingkai Ding, Xiangyong Li, Shaoping Zhu, Xudong Tang   +9 more
doaj   +1 more source

Synergistic Anticancer Activity of Fucoidan from Lessonia trabeculata Combined with Chemotherapeutic Agents in 4T1 Breast Spheroids

Marine Drugs
Triple-negative breast cancer (TNBC) is known for being aggressive and potentially resistant to chemotherapy. This means that new ways to improve cancer treatments are a priority.
Rosa María Condori Macuri, Libertad Alzamora-Gonzales, Erasmo Honorio Colona-Vallejos, Raisa Teresa Cruz Riquelme, Laura Inés Pecho Chávez, Jherson Oscar Cisneros Gutierrez, Victor Alonso Montejo Anlas   +6 more
doaj   +1 more source

Measuring Intratumoral Heterogeneity of Immune Repertoires

Frontiers in Oncology, 2020
There is considerable clinical and fundamental value in measuring the clonal heterogeneity of T and B cell expansions in tumors and tumor-associated lymphoid structures—along with the associated heterogeneity of the tumor neoantigen landscape—but such ...
Diana Vladimirovna Yuzhakova, Lilia N. Volchkova, Mikhail Valerievich Pogorelyy, Mikhail Valerievich Pogorelyy, Ekaterina O. Serebrovskaya, Ekaterina O. Serebrovskaya, Irina A. Shagina, Irina A. Shagina, Ekaterina A. Bryushkova, Ekaterina A. Bryushkova, Tatiana O. Nakonechnaya, Tatiana O. Nakonechnaya, Tatiana O. Nakonechnaya, Anna V. Izosimova, Daria S. Zavyalova, Maria M. Karabut, Mark Izraelson, Mark Izraelson, Mark Izraelson, Igor V. Samoylenko, Vladimir E. Zagainov, Vladimir E. Zagainov, Dmitriy M. Chudakov, Dmitriy M. Chudakov, Dmitriy M. Chudakov, Dmitriy M. Chudakov, Dmitriy M. Chudakov, Elena V. Zagaynova, George Vladimirovich Sharonov, George Vladimirovich Sharonov, George Vladimirovich Sharonov   +30 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Novel Fully Human Antitumor ImmunoRNase Targeting ErbB2-Positive Tumors [PDF]

, 2010
A second generation anti-ErbB2 ImmunoRNase, called Erb-hcAb-RNase, was obtained by the fusion of Erb-hcAb, a human compact anti-ErbB2 antibody, with human pancreatic ribonuclease (HP-RNase or RNase 1).
Borriello, Marianna
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Probiotics as multifaceted oral vaccines against colon cancer: A review

Frontiers in Immunology, 2022
Probiotics are known as the live microorganisms that, upon adequate administration, elicit a health beneficial response inside the host. The probiotics are known as immunomodulators and exhibit anti-tumor properties.
Shubhi Singh, Manisha Singh, Smriti Gaur
doaj   +1 more source