Results 61 to 70 of about 3,197 (112)
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Evaluation of a New Antitussive Agent
New England Journal of Medicine, 1953DEXTRO-3-methoxy-N-methylmorphinan§ hydrobromide (dextromethorphan hydrobromide) is an experimental drug that has shown cough-inhibiting properties in animals, but the degree of this effect in human beings was not known. Therefore, a study was undertaken to determine the antitussive effect of this substance clinically. The merits of another compound of
L J, CASS, W S, FREDERIK
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The Use of Noscapine (Narcotine) as an Antitussive Agent
Diseases of the Chest, 1957and similar compounds is based on a phenanthrene nucleus, whereas Noscapine is an isoquinoline derivative (related to papaverine). It is readily absorbed after oral or parenteral administration, disappears rapidly from the blood stream, and only traces appear in the urine. Its fate is unknown.
M S, SEGAL +2 more
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Clinical pharmacology of antitussive agents
Clinical Pharmacology & Therapeutics, 1962The cough reflex as part of an integrated protective mechanism for adequate bronchoelimination is vital in maintaining the integrity of the pulmonary parenchyma. While it is undoubtedly true that more patients have died from an inability to cough effectively than from the act of coughing itself, adequate control of useless cough is often necessary in ...
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PHARMACOLOGICAL STUDIES ON NEW SYNTHETIC ANTITUSSIVE AGENTS
Canadian Journal of Biochemistry and Physiology, 1958In an attempt to overcome the inherent disadvantage of narcotic antitussive therapy, three basic alkoxy-alkyl esters of phenothiazine-10-carboxylic acid were synthesized and tested for pharmacological activity. These compounds possessed antitussive activity in the cat in the range of activity of codeine.
C I, CHAPPEL, M G, STEGEN, G A, GRANT
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Latency of cough response as a measure of antitussive agents
Clinical Pharmacology & Therapeutics, 1967The cough reflex was stimulated in selected healthy male subjects with a single nebulized threshold dose of citric acid. The essential components of the method were deep inhalation by the subjects and the measurement of the required time to elicit the cough reflex. Prolongation of latency was used as a measure of antitussive action.
B, Calesnick, J A, Christensen
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Pharmacological studies of antitussive agents
2021This thesis was scanned from the print manuscript for digital preservation and is copyright the author. Researchers can access this thesis by asking their local university, institution or public library to make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
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[Cariogenic antitussive agents].
Schweizerische Monatsschrift fur Zahnheilkunde = Revue mensuelle suisse d'odonto-stomatologie, 1978Nine cough mixtures available on the Swiss market and randomly chosen were tested telemetrically. With the exception of Sinecod all syrups effected immediate and long-lasting pH-depressions in interdental plaque. Patients should be informed on the pronounced caries-promoting potential of these medications.
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Novel α7 nicotinic acetylcholine receptor modulators as potential antitussive agents
Bioorganic and Medicinal Chemistry Letters, 2023Anatoly Mazurov +2 more
exaly
The Evaluation of Antitussive Agents
The Journal of Clinical Pharmacology and New Drugs, 1973openaire +2 more sources