Results 71 to 80 of about 5,757 (219)

Identification of New KCNT1‐Epilepsy Drugs by In Silico, Cell, and Drosophila Modeling

open access: yesAnnals of Neurology, Volume 98, Issue 6, Page 1261-1274, December 2025.
Objective Hyperactive KCNT1 potassium channels, caused by gain‐of‐function mutations, are associated with a range of epilepsy disorders. Patients typically experience drug‐resistant seizures and, in cases with infantile onset, developmental regression can follow.
Michael G. Ricos   +9 more
wiley   +1 more source

Measuring Exposure to Opioids Using Self‐Reported Medication Use Data Versus General Practitioner Prescription Records in the UK Biobank Study

open access: yesPharmacoepidemiology and Drug Safety, Volume 34, Issue 12, December 2025.
ABSTRACT Purpose The ongoing global increase in opioid use necessitates studies examining long‐term health impacts. Prospective cohorts frequently rely on self‐reported medication use data which may be subject to several types of bias compared to more objective measurements.
Allison Domingues   +7 more
wiley   +1 more source

Department of Kampo Diagnostics [PDF]

open access: yes, 2007
この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されまし
条 美智子   +3 more
core   +2 more sources

Hierarchical Superposition Framework Reveals the Complex Effects of Natural Medicine Formulas

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 11, November 2025.
A novel hierarchical superposition pharmacological model incorporates the principle of hierarchical structures from physics to simulate the spatiotemporal dynamics of drug combinations, to elucidate the universal law underlying drug combination effects. By modeling cross‐level causal transmission and attenuation, it advances beyond traditional additive
Weifeng Liang   +3 more
wiley   +1 more source

PEDIATRICIAN’S APPROACH TO THE CHOICE OF MEDICATION AGAINST COUGH IN CHILDREN

open access: yesМедицинский совет, 2016
Cough is a common symptom in respiratory pathology which is associated with 30% of all visits to therapist and more than 50% to pediatrician, especially during the period of respiratory infection outbreak.
I. N. Zakharova, I. V. Berezhnaya
doaj   +1 more source

A Review of Antioxidant Activity, Anti‐Inflammatory Properties, Apoptosis‐Regulatory Effects, and Immune System Modulation of Juglans regia L. (Walnut)

open access: yesFood Science &Nutrition, Volume 13, Issue 11, November 2025.
J. regia L. represents a valuable natural source of antioxidants, anti‐inflammatory agents, apoptosis‐regulatory agents, and immunomodulators. The walnut‐rich phytochemical profile contributes to its therapeutic potential in combating oxidative stress and inflammation, regulating apoptosis and immune responses.
Mahboobeh Ghasemzadeh Rahbardar   +2 more
wiley   +1 more source

Acute Brochitis [PDF]

open access: yes, 2006
A 40-year-old man with no underlying lung disease has a 7-day history of mild shortness of breath with exertion, as well as cough that is now productive of purulent sputum. He reports no paroxysms of cough and no contact with ill persons in his community.
Fowler III, Alpha A., Wenzel, Richard P.
core   +1 more source

Drug‐facilitated crime: A review of findings between 2019 and 2023

open access: yesJournal of Forensic Sciences, Volume 70, Issue 6, Page 2442-2464, November 2025.
Abstract Drug‐facilitated crime (DFC) is a criminal act (e.g., assault, robbery, or sexual assault) in which the perpetrator uses drugs to impair the victim's ability to resist, remember, or recognize the crime being committed. Ethanol is commonly implicated in DFC casework, but limited data are published on other substances currently implicated in ...
Meaghan R. Hessler   +2 more
wiley   +1 more source

The effects of Crocus sativus (saffron) and its constituents on nervous system: A review [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2015
Saffron or Crocus sativus L. (C. sativus) has been widely used as a medicinal plant to promote human health, especially in Asia. The main components of saffron are crocin, picrocrocin and safranal. The median lethal doses (LD50) of C.
Mohammad Reza Khazdair   +4 more
doaj  

Chemical composition, efficacy and safety of Pistacia vera (var. Fandoghi) to inactivate protoscoleces during hydatid cyst surgery [PDF]

open access: yes, 2016
At present, various scolicidal agents have been used for inactivation of protoscoleces during hydatid cyst surgery, however, they are associated with serious adverse side effects including sclerosing colangititis (biliary tract fibrosis), liver ...
Fasihi Harandi, Majid.   +4 more
core   +1 more source

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