Results 91 to 100 of about 9,108 (207)

Protein design and RNA design: Perspectives

open access: yesQuantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Advances in deep learning and generative modeling have transformed the landscape of protein and RNA design, enabling rapid and precise creation of novel biomolecules with tailored structures and functions. In protein design, generative deep learning frameworks now support backbone generation, sequence optimization, and joint sequence–structure
Xi Chen, Xu Dai, Peilong Lu
wiley   +1 more source

A randomised controlled trial of two infusion rates to decrease reactions to antivenom.

open access: yesPLoS ONE, 2012
BackgroundSnake envenoming is a major clinical problem in Sri Lanka, with an estimated 40,000 bites annually. Antivenom is only available from India and there is a high rate of systemic hypersensitivity reactions.
Geoffrey K Isbister   +5 more
doaj   +1 more source

Guidelines for Essential Trauma Care: Second Edition (2026)

open access: yesWorld Journal of Surgery, Volume 50, Issue 6, Page 1409-1450, June 2026.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock   +41 more
wiley   +1 more source

High-throughput epitope identification for snakebite antivenom [PDF]

open access: yes, 2015
Insight into the epitopic recognition pattern for polyclonal antivenoms is a strong tool for accurate prediction of antivenom cross-reactivity and provides a basis for design of novel antivenoms.
Engmark, Mikael   +6 more
core  

Low-dose adrenaline, promethazine, and hydrocortisone in the prevention of acute adverse reactions to antivenom following snakebite: a randomised, double-blind, placebo-controlled trial.

open access: yesPLoS Medicine, 2011
BackgroundEnvenoming from snakebites is most effectively treated by antivenom. However, the antivenom available in South Asian countries commonly causes acute allergic reactions, anaphylactic reactions being particularly serious.
H Asita de Silva   +12 more
doaj   +1 more source

Landscape heterogeneity is an important predictor of snake–human encounters in Eswatini

open access: yesJournal of Applied Ecology, Volume 63, Issue 6, June 2026.
Our results suggest that large‐scale land use changes, such as disintegration of natural habitat into smaller patches of habitat, are associated with a significant increased likelihood of encountering a snake. This has important implications for both snakebite prevention and landscape conservation in southern Africa as habitats change and populations ...
Sara Padidar   +4 more
wiley   +1 more source

Antivenom for snake venom-induced neuromuscular paralysis [PDF]

open access: yes, 2017
To assess the effects of antivenom on neuromuscular paralysis in people with neurotoxic snake envenoming.
Maduwage, Kalana   +11 more
core   +1 more source

Antivenom Evaluation by Electrophysiological Analysis

open access: yes, 2017
Scorpion stings on humans are medically relevant because they may contain toxins that specifically target ion channels. During antivenom production, pharmaceutical companies must use a large number of experimental animals to ensure the antivenom’s ...
Lourival D. Possani   +5 more
core   +1 more source

Summary of studies performing 20WBCT after antivenom.

open access: yes, 2021
Summary of studies performing 20WBCT after antivenom.
Eli Harriss (5636576)   +14 more
core   +1 more source

Neutralizing capacity of a new monovalent anti-Bothrops atrox antivenom: comparison with two commercial antivenoms

open access: yesBrazilian Journal of Medical and Biological Research, 1997
Three horse-derived antivenoms were tested for their ability to neutralize lethal, hemorrhagic, edema-forming, defibrinating and myotoxic activities induced by the venom of Bothrops atrox from Antioquia and Chocó (Colombia). The following antivenoms were
R. Otero   +8 more
doaj   +1 more source

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