Results 91 to 100 of about 9,108 (207)
Protein design and RNA design: Perspectives
Abstract Advances in deep learning and generative modeling have transformed the landscape of protein and RNA design, enabling rapid and precise creation of novel biomolecules with tailored structures and functions. In protein design, generative deep learning frameworks now support backbone generation, sequence optimization, and joint sequence–structure
Xi Chen, Xu Dai, Peilong Lu
wiley +1 more source
A randomised controlled trial of two infusion rates to decrease reactions to antivenom.
BackgroundSnake envenoming is a major clinical problem in Sri Lanka, with an estimated 40,000 bites annually. Antivenom is only available from India and there is a high rate of systemic hypersensitivity reactions.
Geoffrey K Isbister +5 more
doaj +1 more source
Guidelines for Essential Trauma Care: Second Edition (2026)
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock +41 more
wiley +1 more source
High-throughput epitope identification for snakebite antivenom [PDF]
Insight into the epitopic recognition pattern for polyclonal antivenoms is a strong tool for accurate prediction of antivenom cross-reactivity and provides a basis for design of novel antivenoms.
Engmark, Mikael +6 more
core
BackgroundEnvenoming from snakebites is most effectively treated by antivenom. However, the antivenom available in South Asian countries commonly causes acute allergic reactions, anaphylactic reactions being particularly serious.
H Asita de Silva +12 more
doaj +1 more source
Landscape heterogeneity is an important predictor of snake–human encounters in Eswatini
Our results suggest that large‐scale land use changes, such as disintegration of natural habitat into smaller patches of habitat, are associated with a significant increased likelihood of encountering a snake. This has important implications for both snakebite prevention and landscape conservation in southern Africa as habitats change and populations ...
Sara Padidar +4 more
wiley +1 more source
Antivenom for snake venom-induced neuromuscular paralysis [PDF]
To assess the effects of antivenom on neuromuscular paralysis in people with neurotoxic snake envenoming.
Maduwage, Kalana +11 more
core +1 more source
Antivenom Evaluation by Electrophysiological Analysis
Scorpion stings on humans are medically relevant because they may contain toxins that specifically target ion channels. During antivenom production, pharmaceutical companies must use a large number of experimental animals to ensure the antivenom’s ...
Lourival D. Possani +5 more
core +1 more source
Summary of studies performing 20WBCT after antivenom.
Summary of studies performing 20WBCT after antivenom.
Eli Harriss (5636576) +14 more
core +1 more source
Three horse-derived antivenoms were tested for their ability to neutralize lethal, hemorrhagic, edema-forming, defibrinating and myotoxic activities induced by the venom of Bothrops atrox from Antioquia and Chocó (Colombia). The following antivenoms were
R. Otero +8 more
doaj +1 more source

