Prophylactic antiviral activity of sulfated glycomimetic oligomers and polymers.
Journal of the American Chemical Society, 2020 In this work, we investigate the potential of highly sulfated synthetic glycomimetics to act as inhibitors of viral binding/infection. Our results indicate that both, long chain glycopolymers and short chain glycooligomers are capable of preventing viral
Laura Soria-Martinez +10 more
semanticscholar +1 more source
Assessment of in-vitro cytotoxicity and in-ovo virucidal antiviral efficacy of various plant extracts and bioactive molecules [PDF]
Kafkas Universitesi Veteriner Fakültesi DergisiThe viral diseases that occurred in recent years have increased the interest in non-toxic to healthy cells and naturally isolated agents to struggle with these diseases.
Furkan Ozan ÇÖVEN +7 more
doaj +1 more source
Viruses, 2023 A limited number of effective therapies are currently available to treat human coronavirus SARS-CoV-2 and other human coronaviruses, which are responsible for nearly a third of global cases of the common cold.
Sabina Andreu +3 more
doaj +1 more source
Single-domain antibodies and their formatting to combat viral infections [PDF]
, 2018 Since their discovery in the 1990s, single-domain antibodies (VHHs), also known as NanobodiesA (R), have changed the landscape of affinity reagents. The outstanding solubility, stability, and specificity of VHHs, as well as their small size, ease of ...
Ballegeer, Marlies +4 more
core +2 more sources
Clinical Pharmacology Perspectives on the Antiviral Activity of Azithromycin and Use in COVID‐19
Clinical pharmacology and therapy, 2020 Azithromycin (AZ) is a broad‐spectrum macrolide antibiotic with a long half‐life and a large volume of distribution. It is primarily used for the treatment of respiratory, enteric, and genitourinary bacterial infections.
B. Damle +4 more
semanticscholar +1 more source
Antiviral Activity of Selected Lamiaceae Essential Oils and Their Monoterpenes Against SARS-Cov-2
Frontiers in Pharmacology, 2022 This study presents the very first report on the in vitro antiviral activity of selected essential oils of Lamiaceae plant species and their monoterpenes against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Sanja Ćavar Zeljković +8 more
doaj +1 more source
Synthesis of 1,4-Disubstituted Mono and Bis-triazolocarbo-acyclonucleoside Analogues of 9-(4-Hydroxybutyl)guanine by Cu(I)-Catalyzed Click Azide-Alkyne Cycloaddition [PDF]
, 2011 A series of novel mono-1,2,3-triazole and bis-1,2,3-triazole acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine was prepared via copper(I)-catalyzed 1,3-dipolar cycloaddition of N-9 propargylpurine, N-1-propargylpyrimidines/as-triazine with the ...
Engels, Joachim W. +2 more
core +2 more sources
Antiviral Activities of Silymarin and Derivatives [PDF]
Molecules, 2019 Silymarin flavonolignans are well-known agents that typically possess antioxidative, anti-inflammatory, and hepatoprotective functions. Recent studies have also documented the antiviral activities of silymarin and its derivatives against several viruses, including the flaviviruses (hepatitis C virus and dengue virus), togaviruses (Chikungunya virus and
Hsin Ya Hsu +3 more
openaire +4 more sources
Antiviral Drug Research Proposal Activity
Journal of Microbiology & Biology Education, 2011 The development of antiviral drugs provides an excellent example of how basic and clinical research must be used together in order to achieve the final goal of treating disease.
Lisa Injaian +4 more
doaj +1 more source
Investigation of the effıciency of pomegranate (punica granatum l.) peel extract on herpes simplex virus-1 [PDF]
Eurasian Journal of Veterinary Sciences, 2022 Aim: This study, it was aimed to determine the antiviral activity of pomegranate peel (Punica granatum L.) extract on HSV-1 in vitro. Materials and Methods: Before evaluating the antiviral efficacy, the cytotoxic activity of different concentrations of ...
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