Results 271 to 280 of about 3,625,809 (366)

Role of indirubin-3'-oxime as antiviral and immunomodulatory agent in influenza H5N1 virus infected human alveolar epithelial cells

, 2012
Sa-rang Kang
openalex   +1 more source

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses

Science Translational Medicine, 2017
T. Sheahan, A. Sims, Rachel L. Graham, Vineet D. Menachery, Lisa E. Gralinski, J. Case, S. Leist, K. Pyrć, Joy Y. Feng, Iva Trantcheva, R. Bannister, Yeojin Park, D. Babusis, M. Clarke, R. Mackman, Jamie E. Spahn, Christopher A. Palmiotti, D. Siegel, A. Ray, T. Cihlář, R. Jordan, M. Denison, R. Baric   +22 more
semanticscholar   +1 more source

Catalytic Amyloids: Turning Fibrils Into Biocatalysts

Chemistry – A European Journal, EarlyView.
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito, Linda Leone, Flavia Nastri, Angela Lombardi   +3 more
wiley   +1 more source

Immunoliposomes As a Promising Antiviral Agent against SARS-CoV-2. [PDF]

Dokl Biochem Biophys
Bobik TV, Simonova MA, Rushkevich NU, Kostin NN, Skryabin GA, Knorre VD, Schulga AA, Konovalova EV, Proshkina GM, Gabibov AG, Deev SM.   +10 more
europepmc   +1 more source

Safety, Tolerability, and Pharmacokinetics of the Novel Antiviral Agent Ensitrelvir Fumaric Acid, a SARS-CoV-2 3CL Protease Inhibitor, in Healthy Adults. [PDF]

Antimicrob Agents Chemother, 2022
Shimizu R, Sonoyama T, Fukuhara T, Kuwata A, Matsuo Y, Kubota R.   +5 more
europepmc   +1 more source

Synthesis and Evaluation of the First Generation of Glycosylated Nucleoside Analogues as Potential Inhibitors of the Base J Metabolism in Kinetoplastid Parasites

Chemistry – A European Journal, EarlyView.
Novel analogues of the kinetoplastid‐specific DNA base J unlock a new way to target parasite epigenetic regulation. Some compounds selectively inhibit Leishmania and Trypanosoma species without harming human cells, revealing a promising route toward innovative antiparasitic therapies.
Océane Monfret, Dan Liu, Manon Louis, Sihem Rebei, Dominique Urban, Yann Bourdreux, Elisabeth Mouray, Philippe Grellier, Gilles Doisneau, Dominique Guianvarc'h   +9 more
wiley   +1 more source

The α-dystroglycan N-terminus is a broad-spectrum antiviral agent against SARS-CoV-2 and enveloped viruses

, 2023
Bigotti MG, Klein K, Gan ES, Anastasina M, Andersson S, Vapalahti O, Katajisto P, Erdmann M, Davidson AD, Butcher SJ, Collinson I, Ooi EE, Balistreri G, Brancaccio A, Yamauchi Y.   +14 more
europepmc   +1 more source

Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential

Proceedings of the National Academy of Sciences of the United States of America, 2011
M. Zasloff, A. P. Adams, B. Beckerman, A. Campbell, Ziying Han, Erik Luijten, I. Meza, J. Julander, Abhijit Mishra, Wei Qu, Johnm . Taylor, S. Weaver, G. Wong   +12 more
semanticscholar   +1 more source

Monodentate Phosphine Modulation in Cyclometallated Platinum(II) Complexes for Antileishmanial, Antiviral, and Antitumor Applications

ChemMedChem, EarlyView.
Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto, Gustavo Clauss, Jennyfer Castro, Marcus S. A. Garcia, Natasha M. Cassani, Bruna C. Sandim, Ana Laura C. Oliveira, Stephanie P. B. Reyes, Nádija N. P. da Silva, Fillipe V. Rocha, Ana C. G. Jardim, Danilo C. Miguel, Camilla Abbehausen   +12 more
wiley   +1 more source

Could Molnupiravir Be the First-Line Alternative Oral Antiviral Agent for COVID-19 Patients at High Risk? [PDF]

J Korean Med Sci
Lee JY.
europepmc   +1 more source