Results 41 to 50 of about 193,162 (335)
Antiviral activity of silver nanoparticles against the influenza A virus
Journal of Virus Eradication, 2023 Viral infections occupy an essential place in modern medicine, particularly a large group of diseases caused by the influenza viruses. They are rapidly transmitted and mutate quickly, which can lead to significant socio-economic consequences.
Krystyna Naumenko +3 more
doaj +1 more source
IFNα and IFNγ Impede Marek’s Disease Progression [PDF]
, 2019 Marek’s disease virus (MDV) is an alphaherpesvirus that causes Marek’s disease, a malignant lymphoproliferative disease of domestic chickens. While MDV vaccines protect animals from clinical disease, they do not provide sterilizing immunity and allow ...
Bertzbach, Luca D. +6 more
core +1 more source
Seven classes of antiviral agents
Cellular and Molecular Life Sciences, 2022 AbstractThe viral epidemics and pandemics have stimulated the development of known and the discovery of novel antiviral agents. About a hundred mono- and combination antiviral drugs have been already approved, whereas thousands are in development. Here, we briefly reviewed 7 classes of antiviral agents: neutralizing antibodies, neutralizing recombinant
Aleksandr Ianevski +7 more
openaire +3 more sources
Cardiovascular risk in chronic hepatitis B patients treated with tenofovir disoproxil fumarate or tenofovir alafenamide [PDF]
Clinical and Molecular HepatologyBackground/Aims Tenofovir disoproxil fumarate (TDF) is known to have a lipid-lowering effect. This is in contrast to tenofovir alafenamide (TAF), which has a lipid-neutral effect.
Hyeyeon Hong +7 more
doaj +1 more source
Discovery of Retro-1 Analogs Exhibiting Enhanced Anti-vaccinia Virus Activity
Frontiers in Microbiology, 2020 Orthopoxviruses (OPXVs) are an increasing threat to human health due to the growing population of OPXV-naive individuals after the discontinuation of routine smallpox vaccination.
Lalita Priyamvada +7 more
doaj +1 more source
mBio, 2021 Virus-host interactions are complicated processes, and multiple cellular proteins promote or inhibit viral replication through different mechanisms. Recent progress has implicated circular RNAs (circRNAs) in cancer biology and progression; however, the ...
Zhiyuan Qu +11 more
doaj +1 more source
A Novel Small Molecule Inhibits Hepatitis C Virus Propagation in Cell Culture
Microbiology Spectrum, 2021 Hepatitis C virus (HCV) can cause acute and chronic infection that is associated with considerable liver-related morbidity and mortality. In recent years, there has been a shift in the treatment paradigm with the discovery and approval of agents that ...
Ahmed K. Oraby +10 more
doaj +1 more source
A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]
, 2017 Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel +1 more
core +2 more sources
In vitro and in vivo antiviral activity of monolaurin against Seneca Valley virus
Frontiers in Veterinary Science, 2023 IntroductionSurveillance of the Seneca Valley virus (SVV) shows a disproportionately higher incidence on Chinese pig farms. Currently, there are no vaccines or drugs to treat SVV infection effectively and effective treatment options are urgently needed ...
Bo Su +11 more
doaj +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source