Results 191 to 200 of about 3,598,763 (344)

Pharmacokinetics of dolutegravir, tenofovir and lamivudine during venous–venous extracorporeal membrane oxygenation (VV‐ECMO): A case report

British Journal of Clinical Pharmacology, EarlyView.
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart, Emiel Leegwater, Thomas H. Ottens, Emile F. Schippers, Erik B. Wilms, David M. Burger, Cees van Nieuwkoop, Liesbeth B. E. Bosma   +7 more
wiley   +1 more source

Prioritizing Feasible and Impactful Actions to Enable Secure AI Development and Use in Biology

Biotechnology and Bioengineering, EarlyView.
ABSTRACT As artificial intelligence continues to enhance biological innovation, the potential for misuse must be addressed to fully unlock the potential societal benefits. While significant work has been done to evaluate general‐purpose AI and specialized biological design tools (BDTs) for biothreat creation risks, actionable steps to mitigate the risk
Josh Dettman, Emily Lathrop, Aurelia Attal‐Juncqua, Matthew Nicotra, Allison Berke   +4 more
wiley   +1 more source

Potential of <i>Artemisia annua</i> Bioactives as Antiviral Agents Against SARS-CoV-2 and Other Health Complications. [PDF]

Pharmaceuticals (Basel)
Shaer NA, Mohamed AA, Schnug E.
europepmc   +1 more source

In vitro antiviral effect of sulfated pectin from Mangifera indica against the infection of the viral agent of childhood bronchiolitis (Respiratory Syncytial Virus - RSV)

Mário Gabriel Lopes Barboza, André Luiz Dyna, Thiago Ferreira de Lima, Eliandro Reis Tavares, Sueli Fumie Yamada‐Ogatta, Flávia Deduch, Alexandre Orsato, Karina Alves Toledo, Arcelina Pacheco Cunha, Nágila Maria Pontes Silva Ricardo, Lígia Carla Faccin‐Galhardi   +10 more
openalex   +2 more sources

Hepatitis B Virus Reactivation in Patients Receiving Interferon-Free Direct-Acting Antiviral Agents for Chronic Hepatitis C Virus Infection [PDF]

, 2017
Chen‐Hua Liu, Chun‐Jen Liu, Tung‐Hung Su, Yu‐Jen Fang, Hung‐Chih Yang, Pei‐Jer Chen, Ding‐Shinn Chen, Jia‐Horng Kao   +7 more
openalex   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Polyphenols as Antiviral Agents: Their Potential Against a Range of Virus Types. [PDF]

Nutrients
Coşkun N, Demir R, Canbolat AA, Sarıtaş S, Pekdemir B, Bechelany M, Karav S.   +6 more
europepmc   +1 more source

Chemical Profiling, In Silico and In Vitro Studies to Identify Potential CDK2 and mTOR Inhibitor From Selaginella inaequalifolia (Hook. & Grev.) Spring Ethanolic Extracts

Chemistry &Biodiversity, EarlyView.
ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy, Sivaraman Arumugam, Robin Charles Antony Arulraj, Anne Wincy Jacob Thomas, Henrique D. M. Coutinho   +4 more
wiley   +1 more source

Treatment guidelines for Hepatitis C in Spain

Revista Española de Sanidad Penitenciaria
The discovery of new orally administered drugs that can block different targets of the replication cycle of the hepatitis C virus (HCV) with major antiviral activity, has revolutionized treatment of this infection and relegated interferon-based ...
M. Crespo-Casal
doaj  

Balancing Host Defense and Viral Tolerance for the Development of Next-Generation Broad-Spectrum Antiviral Agents. [PDF]

Pathogens
Zhao X, Du R, Rong L.
europepmc   +1 more source