Results 21 to 30 of about 4,679,298 (290)

Application of pseudovirus system in the development of vaccine, antiviral-drugs, and neutralizing antibodies

open access: yesMicrobiology Research, 2022
Pseudoviruses are viral particles coated with a heterologous envelope protein, which mediates the entry of pseudoviruses as efficiently as that of the live viruses possessing high pathogenicity and infectivity. Due to the deletion of the envelope protein
Qi Xiang   +4 more
semanticscholar   +1 more source

The therapeutic efficacy of quercetin in combination with antiviral drugs in hospitalized COVID-19 patients: A randomized controlled trial

open access: yesEuropean Journal of Pharmacology, 2021
In this study, the therapeutic efficacy of quercetin in combination with remdesivir and favipiravir, were evaluated in severe hospitalized COVID-19 patients.
Mojtaba Shohan   +7 more
semanticscholar   +1 more source

Clinical management, antiviral drugs and immunotherapeutics for treating monkeypox. An update on current knowledge and futuristic prospects

open access: yesInternational Journal of Surgery, 2022
The of monkeypox (MPX) outbreaks in multiple amid its rising cases. Being a neglected/rare disease, has not been paid on its management and treatment aspects.
Sandip Chakraborty   +7 more
semanticscholar   +1 more source

L3MBTL2-mediated CGA transcriptional suppression promotes pancreatic cancer progression through modulating autophagy

open access: yesiScience, 2022
Summary: L3MBTL2 is a crucial component of ncPRC1.6 and has been implicated in transcriptional repression and chromatin compaction. However, the repression mechanism of L3MBTL2 and its biological functions are largely undefined.
Hua Huang   +8 more
doaj   +1 more source

Sal synthase induced cytotoxicity of PC12 cells through production of the dopamine metabolites salsolinol and N-methyl-salsolinol

open access: yesJournal of Integrative Neuroscience, 2022
As a catechol isoquinoline, salsolinol (Sal) is widely distributed in mammalian brains, and is increased in the cerebrospinal fluid (CSF) and urine of Parkinsonian patients. Sal can be metabolized to N-methyl-salsolinol (NM-Sal), an MPP+-like neurotoxin,
Qianqian Xiong   +7 more
doaj   +1 more source

Detoxifying SARS-CoV-2 antiviral drugs from model and real wastewaters by industrial waste-derived multiphase photocatalysts

open access: yesJournal of Hazardous Materials, 2022
The use of antiviral drugs has surged as a result of the COVID-19 pandemic, resulting in higher concentrations of these pharmaceuticals in wastewater. The degradation efficiency of antiviral drugs in wastewater treatment plants has been reported to be ...
M. Hojamberdiev   +8 more
semanticscholar   +1 more source

Antiviral Drug Allergy [PDF]

open access: yesImmunology and Allergy Clinics of North America, 2014
Antiviral drugs used to treat HIV and hepatitis C are common causes of delayed drug hypersensitivities for which many of the more severe reactions have been recently shown to be immunogenetically mediated such as abacavir hypersensitivity where HLA-B(∗)57:01 is now used routinely as a screening test to exclude patients carrying this allele from ...
Milpied-Homsi, B.   +2 more
openaire   +2 more sources

Current insights into the implications of m6A RNA methylation and autophagy interaction in human diseases

open access: yesCell & Bioscience, 2021
Autophagy is a conserved degradation process crucial to maintaining the primary function of cellular and organismal metabolism. Impaired autophagy could develop numerous diseases, including cancer, cardiomyopathy, neurodegenerative disorders, and aging ...
Xuechai Chen   +6 more
doaj   +1 more source

Development and Effects of Influenza Antiviral Drugs

open access: yesMolecules, 2021
Influenza virus is a highly contagious zoonotic respiratory disease that causes seasonal outbreaks each year and unpredictable pandemics occasionally with high morbidity and mortality rates, posing a great threat to public health worldwide.
Hang Yin   +6 more
semanticscholar   +1 more source

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