Results 131 to 140 of about 140,304 (256)

A primary oseltamivir-resistant mutation in influenza hemagglutinin and its implications for antiviral resistance surveillance. [PDF]

Nat Commun
Zhang L, Shao Y, Zou X, Cui Y, Ding S, Chen Y, Wu Q, Mu S, Li X, Yang Q, Cao B, Deng T.   +11 more
europepmc   +1 more source

A comparison of induced antiviral resistance by the phytoprotein CAP-34 and isolate P1f of the rhizobacterium Pseudomonas putida. [PDF]

3 Biotech, 2021
Gupta AK, Verma J, Srivastava A, Srivastava S, Prasad V.   +4 more
europepmc   +1 more source

Characterization of Lysosomal Hydrolases and Transporters and Their Age‐Dependent Variability: Relevance to Drug Metabolism and Transport of Small Molecule and Biologic Drugs

Clinical Pharmacology &Therapeutics, EarlyView.
Lysosomes play a key role in the accumulation, catabolism, and transport of endogenous and exogenous metabolites and proteins and are involved in drug metabolism and prodrug activation. However, the protein abundance and interindividual variability of lysosomal drug‐metabolizing enzymes and transporters (DMETs) remain underexplored.
Darshak Gadara, Dilip Kumar Singh, Sandhya Subash, Guihua Yue, Deepak Ahire, Chris Bohl, Maciej Czerwinski, Stephanie Helmstetter, Scott Heyward, Robert S. Jones, Cyrus Khojasteh, Ryota Kikuchi, Priyanka Kulkarni, Bin Ma, Bernard Murray, Chris Seib, Bill Smith, David M. Stresser, Mitchell E. Taub, Ting Wang, Bhagwat Prasad   +20 more
wiley   +1 more source

Methionine Synthase Positively Regulates Plant Defence to Both RNA and DNA Viruses and Is Useful for Developing Broad-Spectrum Antiviral Resistance in Crops. [PDF]

Plant Biotechnol J
Wang Z, Zhang K, Zhang C, Yang J, Li B, Wang L, Shi Z, Guo R, Zhang S, Gao K, Li J, Jin X, Ji X, Bi H, You L, Jin H, Wang D.   +16 more
europepmc   +1 more source

Drug resistance and antiviral agents [PDF]

Journal of Antimicrobial Chemotherapy, 1976
openaire   +2 more sources

Bemnifosbuvir: An HCV NS5B Inhibitor With Multiple Modes of Action

Clinical Pharmacology &Therapeutics, EarlyView.
Bemnifosbuvir (BEM) is a potent, pan‐genotypic inhibitor targeting the hepatitis C virus (HCV) NS5B polymerase. Its antiviral activity was evaluated in an ascending dose phase I clinical trial involving 30 patients treated once a day for 7 days. After treatment initiation, plasma HCV RNA declined in a biphasic manner with a mean reduction of 2.3 log10 ...
Carolin Zitzmann, Ruy M. Ribeiro, Aurélien Marc, Xiao‐Jian Zhou, Alan S. Perelson   +4 more
wiley   +1 more source

Correction: Effect of a loss of the mda5/ifih1 gene on the antiviral resistance in a Chinook salmon Oncorhynchus tshawytscha cell line. [PDF]

PLoS One
Collins C, Chaumont L, Peruzzi M, Jamak N, Boudinot P, Béjar J, Moreno P, Torres DÁ, Collet B.   +8 more
europepmc   +1 more source

A Single Nonsynonymous Substitution in the RNA-Dependent RNA Polymerase of Potato virus Y Allows the Simultaneous Breakdown of Two Different Forms of Antiviral Resistance in Capsicum annuum. [PDF]

Viruses, 2023
Moury B, Michon T, Simon V, Palloix A.
europepmc   +1 more source

Learning Strategies from Nature's Blueprint to Cyclic Carbonate Synthesis

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
The development of sustainable synthetic methods for cyclic carbonates draws inspiration from nature, focusing on eco‐friendly processes and renewable resources like CO2 and biomass. This review explore various CO2 activation mechanisms, green chemistry principles, and green catalysts.
Erika Saccullo, Vincenzo Patamia, Chiara Zagni, Antonio Rescifina, Giuseppe Floresta   +4 more
wiley   +1 more source

Receptor-like kinases BIR1 and BIR3 modulate antiviral resistance by different mechanisms. [PDF]

New Phytol
Robinson C, Guzmán-Benito I, Sede AR, Elvira-González L, Hua C, Ciska M, Nürnberger T, Heinlein M, Llave C.   +8 more
europepmc   +1 more source