Results 161 to 170 of about 2,451,260 (295)

Orally bioavailable RORγ/DHODH dual host-targeting small molecules with broad-spectrum antiviral activity

Host-directed antivirals (HDAs) represent an attractive treatment option and a strategy for pandemic preparedness, especially due to their potential broad-spectrum antiviral activity and high barrier to resistance development.
Sparrer, Konstantin M. J., Hahn, Friedrich, Pfaender, Stephanie, Ensser, Armin, Gege, Christian, Dobner, Thomas, Cynis, Holger, Reuter, Sebastian, Vitt, Daniel, Groß, Rüdiger, Kohlhof, Hella, Ip, Wing-Hang, Hietel, Benjamin, Hunszinger, Victoria, Issmail, Leila, Wagner, Sabrina, Cordsmeier, Arne, Kögler, Melanie, Uhlig, Nadja, Münch, Jan, Irrgang, Pascal, Tenbusch, Matthias, Herrmann, Alexandra, Wangen, Christina, Grunwald, Thomas, Weil, Tatjana, Eberlein, Valentina, Heinen, Natalie, Klopfleisch, Robert   +28 more
core   +1 more source

Sierra SARS-CoV-2 sequence and antiviral resistance analysis program. [PDF]

J Clin Virol, 2022
Tzou PL, Tao K, Sahoo MK, Kosakovsky Pond SL, Pinsky BA, Shafer RW.   +5 more
europepmc   +1 more source

Drug resistance and antiviral agents [PDF]

Journal of Antimicrobial Chemotherapy, 1976
openaire   +2 more sources

Antiviral Resistance in Influenza: Clinical and Public Health Implications. [PDF]

Influenza Other Respir Viruses
Ngiam JN, Koh MCY, Hayden FG.
europepmc   +1 more source

High Frequency of Antiviral Resistance Mutations in HBV Genotypes A2 and H: Multidrug Resistance Strains in Mexico. [PDF]

J Clin Transl Hepatol, 2023
Jose-Abrego A, Roman S, Rebello Pinho JR, Gomes-Gouvêa MS, Panduro A.   +4 more
europepmc   +1 more source

Antiviral Res [PDF]

The 32nd International Conference on Antiviral Research (ICAR), sponsored by the International Society for Antiviral Research (ISAR), was held in Baltimore, Maryland, USA, on May 12-15, 2019.

core  

Targeting TaNSUN2 provides a potential route to combine antiviral resistance with improved productivity in wheat. [PDF]

Front Microbiol
Jia Q, Zhou Y, Yu W, Li J.
europepmc   +1 more source

A strategy for evaluating potential antiviral resistance to small molecule drugs and application to SARS-CoV-2. [PDF]

Sci Rep, 2023
Sargsyan K, Mazmanian K, Lim C.
europepmc   +1 more source

Antiviral Resistance Associated With Multiple Mutations Occurring in Seasonal Influenza A(H3N2) Virus in a Patient Treated With Oseltamivir. [PDF]

Clin Case Rep
Hussain S, Guo C, Deng YM, Deshpande N, Chanthalavanh P, Spirason N, Burmas L, Peck H, Gardiner BJ, Barr IG.   +9 more
europepmc   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source