Results 171 to 180 of about 135,285 (241)

PD‐1/PD‐L1 in Hepatocellular Carcinoma (2014–2024): A Combined Macro and Micro Analysis of Immunotherapy Implications

open access: yesiNew Medicine, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) represents a significant global health issue, with the PD‐1/PD‐L1 axis serving a pivotal target for immunotherapy in this malignancy. However, a comprehensive bibliometric analysis of PD‐1/PD‐L1 research in HCC is lacking.
Xingyu Zhu   +4 more
wiley   +1 more source

syn-tasiRnas targeting the coat protein of potato virus Y confer antiviral resistance in Nicotiana benthamiana. [PDF]

open access: yesPlant Signal Behav
Zhao X   +10 more
europepmc   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

open access: yesiNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng   +3 more
wiley   +1 more source

An Evaluation of a Molecular Point‐of‐Care Testing System Designed for Early Diagnosis of Mycoplasma pneumoniae and Respiratory Syncytial Virus Infections

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
On the basis of RT‐qPCR results, 549 oropharyngeal swabs were classified into four groups: MP‐positive (n = 109), MP‐negative (n = 160), RSV‐positive (n = 122), and RSV‐negative (n = 158). Using these as the reference standard, we evaluated a molecular point‐of‐care testing (mPOCT) system (EasyNAT) for simultaneous MP and RSV detection.
Yang Su   +13 more
wiley   +1 more source

Mortality after broad‐ versus narrow‐spectrum antibiotic treatment for patients with nursing and healthcare‐associated pneumonia: A nationwide retrospective cohort study

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background Nursing and healthcare‐associated pneumonia (NHCAP) is defined as pneumonia occurring in individuals with frequent healthcare contact, such as residents of care facilities or patients with impaired activities of daily living. The effectiveness of broad‐spectrum antibiotics in treating NHCAP remains unclear.
Jumpei Taniguchi   +4 more
wiley   +1 more source

Raman Signature of the Wings of the Globe Skimmer Dragonfly: Pantala flavescens

open access: yesJournal of Raman Spectroscopy, EarlyView.
Raman spectroscopy is used to confirm the presence of aliphatic and aromatic hydrocarbons and related derivatives including aldehydes, halides, alcohols, acids, esters, and phenols on the wings of Pantala flavescens. The analysis indicates that wing‐surface lipid composition is largely consistent across the three main ecological zones in Ghana. Notably,
Rachel Desulme   +19 more
wiley   +1 more source

Predicting antiviral resistance mutations in SARS-CoV-2 main protease with computational and experimental screening

open access: yes, 2022
Sasi VM   +7 more
europepmc   +1 more source

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