Unveiling the Molecular Mechanism of Intestinal Metabolite para-Cresol in Modulating Neuroinflammation and Synaptic Dysfunction: Implications for Autism Spectrum Disorder. [PDF]
Here we investigated the effect of p‐Cresol on different brain‐cell types to speculate on their specific contribution to autism spectrum disorder (ASD) synaptic dysfunctions. Our in vitro data show that p‐Cresol impairs dendritic arborization and length, disrupts the excitatory/inhibitory balance, and induces glial activation and inflammatory responses.
Liao W +9 more
europepmc +2 more sources
Opicapone in Parkinson's Disease on Levodopa-Carbidopa Intestinal Gel Treatment: A Pilot, Randomized Study. [PDF]
ABSTRACT Background Levodopa‐carbidopa intestinal gel infusion (LCIG) is an effective therapy for advanced Parkinson's disease (PD). Opicapone (OPC) is an enzyme inhibitor that enhances the bioavailability of levodopa in the brain. Objectives This study evaluates the effect of Opicapone addition in PD‐LCIG patients, assessing its impact on motor ...
Colucci F +9 more
europepmc +2 more sources
Associations of plasma p-tau231 with serial position recall performance in free-of-dementia individuals. [PDF]
Abstract Cognitive assessment and analysis of plasma biomarkers are lower‐cost options for the early assessment of Alzheimer's disease (AD). In this study, we examined whether serial position markers in the Rey's AVLT were sensitive to plasma AD biomarkers in cognitively unimpaired older individuals.
Bruno D +6 more
europepmc +2 more sources
Concordance and Clinical Outcomes Improvement Following Oral Hygiene Motivation: A Systematic Review and Report of the Workshop of the Italian Societies of Dental Hygiene. [PDF]
Aim: A workshop on concordance and oral hygiene was held in February 2024. To address the topic, a systematic review aimed at investigating the effectiveness of motivational interventions in improving oral hygiene and focusing on periodontal clinical indices outcomes was designed.
Abbinante A +16 more
europepmc +2 more sources
The neurobiological foundation of effective repetitive transcranial magnetic brain stimulation in Alzheimer's disease. [PDF]
Abstract Noninvasive brain stimulation (NIBS) techniques, such as repetitive transcranial magnetic stimulation (rTMS), are promising candidate therapeutics for Alzheimer's disease (AD). We review the evidence supporting the fundamental mechanisms of action of rTMS treatments in AD.
Antonioni A +4 more
europepmc +2 more sources
HR practices and work relationships: A 20 year review of relational HRM research
Abstract We systematically reviewed quantitative studies of phenomena at the nexus of Human Resource Management (HRM) and interpersonal relationships. We report on the overall prevalence and trends in research methods relating to construct, internal, external, and statistical conclusion validity.
Anindita Roy Bannya +2 more
wiley +1 more source
Abstract After the Seveso disaster occurred more than 40 years ago, there has been an increasing awareness of the potential impacts that similar accident events can occur in a wide range of process establishments, where the handling and production of hazardous substances pose a real threat to society and the environment.
Mirco Peron +4 more
wiley +1 more source
Person‐organization fit theory and research: Conundrums, conclusions, and calls to action
Abstract The article presents a personal historical review of the person‐organization fit (PO) literature by Amy Kristof‐Brown, Benjamin Schneider and Rong Su. We present six conundrums and research evidence about each that we've encountered while studying fit during our careers: (1) What exactly is PO fit?—the term can be narrowly or broadly defined ...
Amy Kristof‐Brown +2 more
wiley +1 more source
Dalla Cina con rigore. Chung Kuo di Michelangelo Antonioni (molti?) anni dopo
Dalla Cina con rigore.
Paolo Caponi
doaj +1 more source
¿Está dirigido el 'Arte Nuevo' a una minoría especialmente dotada? El caso de Michelangelo Antonioni
El artículo trata de reflexionar sobre aquellos cambios que se producen en la recepción de los filmes de Michelangelo Antonioni por parte de un espectador al que, como receptor de películas hollywoodienses, principalmente, se le exige con este otro cine,
Ana MELENDO CRUZ
doaj +3 more sources

