Results 191 to 200 of about 338,477 (271)

CDKN2A deletion in p16‐negative/HPV‐positive head and neck squamous cell carcinoma: Highlighting the molecular basis behind the limitation of relying on p16 immunohistochemistry as a surrogate marker for HPV involvement

open access: yesHistopathology, Volume 88, Issue 3, Page 664-672, February 2026.
We present a case series of HPV‐positive non‐keratinizing squamous cell carcinoma of the head and neck with discordant negative p16 staining due to CDKN2A deletion. These findings highlight the genomic basis behind the diagnostic pitfall of reliance on p16 immunohistochemistry as a surrogate marker of HPV and raise practice‐changing considerations for ...
Trevor Teich   +8 more
wiley   +1 more source

European Code Against Cancer, 5th edition – cancer‐causing infections and related interventions

open access: yesMolecular Oncology, Volume 20, Issue 1, Page 96-116, January 2026.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations related to cancer‐causing infections, namely H. pylori, HPV, HBV, HCV and HIV, positioned as recommendation number 12.
Catharina Johanna Alberts   +18 more
wiley   +1 more source

Determining optimal GTV‐to‐PGTV margins for CT‐guided dose‐escalated radiotherapy with daily image guidance in locally advanced rectal cancer

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 1, January 2026.
Abstract Background Neoadjuvant chemoradiotherapy for locally advanced rectal cancer yields pathological complete response rates of only 10%–20%. Dose‐escalation strategies may improve outcomes, but optimal GTV‐to‐PGTV margins for CT‐guided radiotherapy with daily IGRT remain undefined.
Xi Qi   +12 more
wiley   +1 more source

Safety and Efficacy of Pelvic Reinforcement Procedure for Preventing Postoperative Perineal Hernia After Robotic Abdominoperineal Resection: A Single‐Center, Retrospective Cohort Study

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 1, Page 128-136, January 2026.
This study aimed to investigate the safety and efficacy of pelvic reinforcement procedure (PRP) in robotic abdominoperineal resection (Ro‐APR). PRP‐ had a significantly higher rate of imaged perineal hernia (PH) (39.2% vs. 6.7%, p = 0.005) and symptomatic PH (19.6% vs.
Yoshihiro Sakai   +8 more
wiley   +1 more source

Gastric Distension Index: A Novel Radiographic Marker Associated With Postoperative Gastric Stasis After Gastrectomy

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 1, Page 103-112, January 2026.
This study introduces the Hiki Index (HI), a novel radiographic metric based on upright abdominal X‐rays, to objectively assess postoperative gastric dilatation after gastrectomy. The HI demonstrated strong predictive value for gastrointestinal symptoms and the need for therapeutic intervention, offering a practical tool for early detection and ...
Hiroki Harada   +9 more
wiley   +1 more source

Causes of death after surgery among cancer patients: a population-based cohort study. [PDF]

open access: yesInt J Surg
Hao Y   +10 more
europepmc   +1 more source

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