Results 211 to 220 of about 18,068 (256)

Synthesis, Photophysical Characterization, and Anticancer Evaluation of Novel Furochromene Derivatives

open access: yesChemistryOpen, Volume 15, Issue 6, June 2026.
This is the first study on novel furochromene derivatives. A series of novel furochromen derivatives, namely (2E)‐1‐(6‐hydroxy‐4,7‐dimethoxy‐1‐benzofuran‐5‐yl)‐3‐arylprop‐2‐en‐1‐ones 4a–c, were synthesized via the Knoevenagel condensation of 6‐hydroxy‐4,7‐dimethoxybenzofuran‐5‐ylethanone 2 with various aromatic aldehydes.
Amal Rabahi   +9 more
wiley   +1 more source

Synthesis, X‐Ray Analysis, Anticancer Activity, Computational, and in Silico Studies of New Thiophene Pyrazole Conjugates

open access: yesChemistryOpen, Volume 15, Issue 6, June 2026.
Two new thiophene–pyrazole derivatives, 8a and 8b, were synthesized from thiophene 3 precursor and fully characterized. The structure of 8a was confirmed by single‐crystal X‐ray diffraction, which revealed a nonplanar conformation stabilized by NH···O hydrogen bonding and weak intermolecular contacts.
Abdullatif Bin Muhsinah   +3 more
wiley   +1 more source

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang   +3 more
wiley   +1 more source

Long-term outcomes and anorectal functional status of patients with anal squamous cell carcinoma treated with the modern technique of intensity-modulated radiotherapy. [PDF]

open access: yesBMC Cancer
Xu T   +17 more
europepmc   +1 more source

A Combined Colon Organoid‐Sensory Neuron Model Reveals Epithelial Contribution to Moringin Efficacy Against Painful Inflammatory Bowel Disease

open access: yesPhytotherapy Research, Volume 40, Issue 6, Page 3250-3266, June 2026.
Experimental workflow and main findings of the study. ABSTRACT Visceral pain is a major symptom of inflammatory bowel diseases (IBDs), requiring effective treatment strategies. Gut epithelium, beyond maintaining barrier integrity and microbiota homeostasis, modulates neurosensorial circuitries, influencing visceral sensitivity.
Francesco Margiotta   +7 more
wiley   +1 more source

The outcomes of Swenson's pull-through in six cats with colorectal adenocarcinoma. [PDF]

open access: yesJ Vet Med Sci
Takahashi Y   +10 more
europepmc   +1 more source

Reactive Infectious Mucocutaneous Eruption (RIME): An Australian Case Series

open access: yesAustralasian Journal of Dermatology, Volume 67, Issue 4, Page 241-246, June 2026.
ABSTRACT Whilst Reactive Infectious Mucocutaneous Eruption (RIME) displays a low mortality rate, the condition results in significant morbidity and resource allocation, including prolonged hospital admission. As such, early diagnosis and optimisation of treatment is imperative.
Hamish Moore   +2 more
wiley   +1 more source

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