Concomitant <i>RAS</i> and <i>BRAF</i> V600E Mutations in Unresectable Metastatic CRC: A Case of Long-term Survival. [PDF]
Kitagawa K +8 more
europepmc +1 more source
Primary Cancer Prevention Through Vaccination: Advances, Challenges, and Global Perspectives
ABSTRACT Oncogenic viral and bacterial infections constitute a significant portion of the global cancer burden, accounting for up to 15% of cases, particularly in low‐ and middle‐income countries. Prophylactic vaccination thus appears to be the most effective tool for preventing these preventable cancers, especially those linked to human papillomavirus
Christian Tague +5 more
wiley +1 more source
Melanomas (amelanotic type) in albino rats. [PDF]
Kurotaki T, Sato J, Tsuchitani M.
europepmc +1 more source
Safety and efficacy of weekly adalimumab 80 mg therapy in pediatric Crohn's disease
Abstract Objectives Adalimumab is commonly used to induce and maintain remission in pediatric Crohn's disease (CD). However, data on the efficacy and safety of high‐dose adalimumab in this population are limited. This study aimed to evaluate the therapeutic effectiveness and safety of weekly high‐dose adalimumab (80 mg) in pediatric CD patients ...
Eyal Cohen‐Sela +9 more
wiley +1 more source
Preoperative and Pathological Discrepancies in Colorectal Cancer: A Single-Institution Retrospective Analysis Based on Mismatch Repair/<i>BRAF</i> V600E Status. [PDF]
Iwata Y +9 more
europepmc +1 more source
Anti‐CD3 antibody induced ultra‐rapid jejunal injury with vascular congestion and edema, followed by gradual recovery. FADD‐DN mice showed exacerbated edema during injury yet accelerated remission during recovery, along with enhanced recruitment of macrophages, neutrophils, and CD4+ T cells and distinct fecal microbiota changes.
Huangru Xu +11 more
wiley +1 more source
HPV awareness and anal cancer prevention among sexual minority men living with HIV in Nigeria: insights from an affirming clinical setting. [PDF]
Volpi CR +15 more
europepmc +1 more source
Historical Records of Tumours in New Zealand Marine Fishes
Tumours were first described in New Zealand marine fishes in 1982 but those early records have been difficult to access and subsequently few tumours have been collected and little has been published. This review updates records of identified tumours from teleosts in the New Zealand marine environment and may encourage more work to identify background ...
John Brian Jones
wiley +1 more source
Age-specific trends in colorectal, appendiceal, and anal tumour incidence by histological subtype in Australia from 1990 to 2020: a population-based time-series analysis. [PDF]
Meyers AL +6 more
europepmc +1 more source
Evaluation of Photophysical Properties and Biological Applications of Diarylmethanes
The wide applications of diarylmethanes were investigated through various experimental and computational approaches. The solvent environment influences the electronic properties of diarylmethanes and hence their drug‐like properties. Interactions with PARP1 revealed stable binding supporting anticancer potential.
H. Ranjini Jenifer +2 more
wiley +1 more source

