Results 41 to 50 of about 471,129 (282)

A importância da anuscopia de alta resolução para o diagnóstico do papilomavírus humano anorretal na forma subclínica, das lesões anais intraepiteliais e do carcinoma "in situ"anal

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: A doença causada pelo Papilomavírus Humano (HPV) tem alta incidência na população e é considerada pré-neoplásica. O objetivo deste trabalho é estudar um método que detecte o HPV anorretal na sua forma subclínica e suas alterações neoplásicas, a
João Carlos Magi, Marcos Ricardo da Silva Rodrigues, Wladimyr Dias Moreno, João Baptista de Paula Fraga, Anderson da Costa Lino Costa, Galdino José Sitônio Formiga   +5 more
doaj   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Anal cancer: an essay on etiology, risk conditions, vulnerability, and care of carriers

DST, 2022
 Introduction: The incidence of anal cancer is influenced by individual factors and socially determined conditions of vulnerability. In Brazil, it has increased in recent decades.
William Pereira Santos, Nathália Barbosa do Espírito Santo Mendes, Alcindo Antônio Ferla   +2 more
doaj   +1 more source

Human papillomavirus-associated subsequent malignant neoplasms among childhood cancer survivors.

Cancer Epidemiology
OBJECTIVE Emerging evidence suggests a higher risk of human papillomavirus-associated subsequent malignant neoplasms (HPV-SMNs) in childhood cancer survivors. However, comprehensive population-based risk estimates for HPV-SMNs are lacking.
Yige Jia, Xu Liu, Xiang Li, Kan Wu
semanticscholar   +1 more source

Genetics of Myeloproliferative Neoplasms. [PDF]

, 2021
Myeloproliferative neoplasms are hematopoietic stem cell disorders based on somatic mutations in JAK2, calreticulin, or MPL activating JAK-STAT signaling.
Meyer, Sara C., Szybinski, Jakub
core   +2 more sources

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Metastatic or Locally Recurrent Anal Squamous Cell Carcinoma (SCAC): Current Clinical Trial Landscape and Novel Approaches

Cancer Management and Research, 2022
Jane E Rogers,1 Michael Leung,1 Benny Johnson2 1U.T. M.D. Anderson Cancer Center, Pharmacy Clinical Programs, Houston, TX, USA; 2U.T. M.D. Anderson Cancer Center, Department of Gastrointestinal Medical Oncology, Houston, TX, USACorrespondence: Jane E ...
Rogers JE, Leung M, Johnson B
doaj  

Advanced Imaging of Pancreatic Neoplasms

, 2022
Imaging has a pivotal role in pancreatic neoplasms, ranging from diagnosis to treatment monitor. It is crucial, especially for pancreatic ductal adenocarcinoma (PDAC), to obtain an early diagnosis, since the therapeutic approach is mainly surgical and ...
Cardobi N., De Robertis R., D'Onofrio M.
core   +1 more source

Low SLC8A1 in Colorectal Cancer Dictates Radiotherapy Resistance Through Calcium‐Dependent ANXA2+sEVs Driving M2 Polarization of TAMs

Advanced Science, EarlyView.
SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang, Jinghan Zhu, Qian Xiao, Qichun Wei, Xiujing He, Ping Li, Kai Jiang, Yue Liu, Yeting Hu, Weiwei Yu, Chuansheng Guo, Sheng Chen, Jian Zhao, Siqi Dai, Jingsun Wei, Hang Yang, Tongtong Bu, Kefeng Ding, Haiyan Chen   +18 more
wiley   +1 more source

Circulating vascular endothelial growth factor and cancer risk: A bidirectional mendelian randomization

Frontiers in Genetics, 2022
In observational studies, circulating vascular endothelial growth factor (VEGF) has been reported to be associated with certain types of cancer. The purpose of this study was to verify whether there is a causal relationship between circulating VEGF and ...
Hong Wu, Tianjun Ma, Dongli Li, Mei He, Hui Wang, Ying Cui   +5 more
doaj   +1 more source