Targeting Intracellular Calcium Stores Alleviates Neurological Morbidities in a DFP-Based Rat Model of Gulf War Illness [PDF]
Gulf War Illness (GWI) is a chronic multi-symptom disorder afflicting the veterans of the First Gulf War, and includes neurological symptoms characterized by depression and memory deficits.
Blair, Robert+3 more
core +1 more source
The study investigates the sedative potential of naringenin (NAR) through in vivo and in silico approaches. NAR significantly enhances sleep duration and reduces latency in mice, especially when combined with diazepam. Molecular docking shows strong binding to GABAA receptors, suggesting a GABAergic mechanism.
Dipu Bishwas+8 more
wiley +1 more source
This study presents a novel, rapid method for in situ functionalization of carbon electrodes using redox‐active form of the 6‐hydroxyflavone. The resulting multiwalled carbon nanotubes with redox‐active HFLA (MWCNT@HFLA‐Redox) electrode enables sensitive, selective detection of toxic phenylhydrazine, with excellent performance (limit of detection: 7 nM)
Valisireddy Lavanya+2 more
wiley +1 more source
Evaluation of anxiolytic potential of Linum usitatissimum oil in wistar rats
The objective of the present study was to evaluate the anxiolytic potential of the Linum usitatissimum (Flax seed) oil (5ml and 2.5ml/kg) in wistar rats by using Elevated plus maze (EPM) model and 5ml and 10 ml/kg in Lithium induced head twitches model ...
Trilochan Satapathy+3 more
doaj
Opioid consumption after lower limb amputation in Medicare beneficiaries
Abstract Background Despite targeted national quality improvement initiatives, opioid prescription and use patterns after lower limb amputation are not well studied. Objective To determine risk factors associated with extended opioid use and rates of high‐risk opioid prescribing after lower limb amputation. Design and setting A retrospective population‐
Alexander N. Khouri+5 more
wiley +1 more source
Comparing the effectiveness of clomipramine and fluoxetine in dogs with anxiety-related behaviours
PICO Question In dogs with anxious behaviours, is fluoxetine more effective than clomipramine in reducing anxiety-related behaviours? Clinical bottom line Category of research Treatment.
Olivia Williamson+5 more
doaj +1 more source
Translating Research to Practice for Children With Autism Spectrum Disorder: Part 2: Behavior Management in Home and Health Care Settings [PDF]
Introduction Managing home and health care for children with autism spectrum disorder can be challenging because of the range of symptoms and behaviors exhibited. Method This article presents an overview of the emerging science related to the methods to
Bultas, Margaret W.+3 more
core +1 more source
The profiles of interaction of yohimbine with anxiolytic and putative anxiolytic agents to modify 5‐HT release in the frontal cortex of freely‐moving rats [PDF]
Celine H.K. Cheng+3 more
openalex +1 more source
After decades of dramatic reductions in their populations, Italian wolves have begun recolonizing parts of their historic range. This growth in populations can lead to potential conflicts with human activities, which remain the main cause of wolf mortality.
Ilaria Troisio+8 more
wiley +1 more source
Reduction in Dressing Change Burden in Patients With Epidermolysis Bullosa—Impact of Oleogel‐S10
ABSTRACT Epidermolysis bullosa (EB) is a severe genetic disorder marked by skin fragility and blistering from minimal trauma. Management relies on frequent and painful dressing changes. The EASE study (NCT03068780), the largest to date in EB, previously demonstrated accelerated wound healing and reduced wound burden for Oleogel‐S10 (birch triterpenes ...
Anna L. Bruckner+9 more
wiley +1 more source