Results 161 to 170 of about 47,485 (252)

Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis

International Journal of Dermatology, Volume 65, Issue 12, Page 2497-2508, December 2026.
Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller, Helmut Beltraminelli, Wolf‐Henning Boehncke, Maximilian Böhm, Antonio Cozzio, Peter Häusermann, Ahmad Jalili, Antonios G. A. Kolios, Claudia Lang, Eva Loos, Christoph Schlapbach, Curdin Conrad   +11 more
wiley   +1 more source

Staff-mediated doll therapy in Chinese residential dementia care: an exploratory pilot and feasibility mixed-methods cluster randomized clinical trial. [PDF]

Front Public Health
Cui Z, Guan R, Xue T, Sun Y, Tan MP, Said MA, Cao Y.   +6 more
europepmc   +1 more source

Cancer co‐medication quality in older patients with polypharmacy: A large randomized trial testing a medication review versus usual care

Journal of Internal Medicine, Volume 300, Issue 6, Page 802-820, December 2026.
Abstract Background Evidence from randomized controlled trials (RCTs) testing medication reviews in geriatric oncology is sparse. Methods We conducted a single‐blinded RCT in ten rehabilitation clinics across Germany. Patients with common cancers, aged ≥ 65 years, and polypharmacy (regularly ≥ five drugs) were randomly allocated in equal proportions to
Miriam Degen, Annette Kopp‐Schneider, Tomislav Vlaski, Sigrid Carlsson, Peter Hallermann, Ludmilla Jewlanowa, Jana Barinoff, Valentin Goede, Christian Lüders, Thomas Kiefer‐Trendelenburg, Diana Lüftner, Jasmin Doll, Jürgen Wagner, Birgit Leibbrand, Hermann Brenner, Ben Schöttker   +15 more
wiley   +1 more source

Isothiocyanate-Rich Essential Oil of <i>Morisonia flexuosa</i> L. Exhibits Anxiolytic-like Effects That May Involve Serotonergic Pathways in Zebrafish. [PDF]

Plants (Basel)
Rodrigues FFG, Carvalho NKG, Souza GGO, Santos HSD, de Menezes IRA, Barros Alves AM, Menezes JESA, Rodrigues FFG, Costa JGMD.   +8 more
europepmc   +1 more source

Proto‐Panic Modulation by Caffeine‐Proteinoid Complexes

Journal of Applied Polymer Science, Volume 143, Issue 41, November 5, 2026.
Caffeine–proteinoid microspheres synthesized by thermal polymerization exhibit compartmentalized drug loading with encapsulation efficiencies of 61%–82% and triphasic release kinetics. Electrochemical monitoring reveals multi‐scale oscillatory dynamics consistent with chaotic and damped harmonic behavior, while Boolean logic operations demonstrate ...
Panagiotis Mougkogiannis, Andrew Adamatzky   +1 more
wiley   +1 more source

RETRACTED: Masataka, N. Possible Anxiolytic Effects of Cannabidiol (CBD) Administration on Feline Responses to a Fear Response Test. <i>Animals</i> 2025, <i>15</i>, 1642. [PDF]

Animals (Basel)
Masataka N.
europepmc   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, Volume 13, Issue 61, 3 November 2026.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Sedative Potential of L (+)‐Tartaric Acid: Behavioral Evidence With In Silico Insights Into Possible GABAergic Interaction

Brain and Behavior, Volume 16, Issue 11, November 2026.
ABSTRACT Purpose Insomnia is a prevalent neurological disorder often caused by stress, anxiety, and imbalances in the GABAergic system. Although benzodiazepines like diazepam (DZP) are commonly prescribed, their long‐term use is associated with adverse effects, including dependence and impaired coordination.
Sumaya Akter Bithi, Anike Chakrabarty, Khadija Akter, Chinmoy Kumar Saha, Mohammad Y. Alshahrani, Md. Arif Hossain, Emon Mia, Noshin Tasnim Yana, Afiya Ajmee, Proma Mandal, Md. Sakib Al Hasan, Muhammad Torequl Islam   +11 more
wiley   +1 more source

Pharmacological Assessment of <i>Calamus guruba</i> Methanolic Extract: Multitarget Effects on Diabetes, Inflammation, Anxiety, and Depression. [PDF]

Food Sci Nutr
Uddin M, Shorna TA, Suma KJ, Ekram MEH, Rana M, Mamun MJI.   +5 more
europepmc   +1 more source