Results 141 to 150 of about 47,485 (252)

Synthesis, Spectroscopic Characterization, Molecular Docking Studies Toward the GABA_A Receptor, ADMET Prediction, GABA Aminotransferase Inhibition, and Anxiolytic Evaluation of Novel Thiazine Derivatives. [PDF]

Pharmaceuticals (Basel)
Sonu, Thajudeen KY, Alshehri SA, Ahmed MM, Porwal M, Verma S.   +5 more
europepmc   +1 more source

Prevalence and Factors Associated With Falls in Individuals Aged 50 Years and Older Living in Urban and Rural Areas in Brazil: A Cross‐Sectional Analysis

Physiotherapy Research International, Volume 32, Issue 1, January 2027.
ABSTRACT Background and Purpose The factors associated with falls may differ from urban to rural areas. However, there is a paucity of studies investigating this topic. To investigate the prevalence and factors associated with falls in individuals aged 50 years and older living in urban and rural areas.
Stéfany Giacomello Piccinin, Merly Fernanda Illera Castellanos, Victória Possebon Sgaria, Bárbara Niegia Garcia de Goulart, Felipe Barreto Schuch, Debora Tornquist, Carine Cristina Callegaro   +6 more
wiley   +1 more source

The anxiolytic effect of dexmedetomidine in adult perioperative patients: a systematic review with meta-analysis of randomized controlled trials. [PDF]

Front Psychiatry
Yang K, Cui JZ, Wang WJ, Yang JX.
europepmc   +1 more source

Efficacy of Mindfulness and Cognitive Behavioral Therapies for Depression and Anxiety in Individuals With Cancer: A Meta‐Analysis

Advanced Oncology, Volume 1, Issue 1, December 2026.
A meta‐analysis of 96 randomized controlled trials (RCTs) involving 14 937 adults with cancer shows that both cognitive behavioral therapy (CBT) and mindfulness‐based interventions (MBIs) reduce anxiety and depression. CBT demonstrates larger overall effects, whereas MBIs provide sustained benefits and perform well in digital formats, supporting ...
Kenni Wojujutari Ajele, Erhabor Sunday Idemudia   +1 more
wiley   +1 more source

Integrated Phytochemical Characterisation, Pharmacological Evaluation and Computational Investigation of Acampe papillosa Stem Extract

Analytical Science Advances, Volume 7, Issue 2, December 2026.
The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Qurratul Ain Sadia, Sadia Tamanna Tamim, Faruq Mohammed Tashriq, Nasir Uddin, Fatematus Zhohara Alam Hima, Ulfat Sobha Surat, Mily Khastagir, Muhammad Abdul Jalil, Md. Hossain Rasel, Arman Ullah Rafi, S. M. Moazzem Hossen   +10 more
wiley   +1 more source

Whispering Inflammation: Sex Shapes Responses to Chronic Low‐Grade Endotoxemia Across Behavior, Brain, and Metabolism

Comprehensive Physiology, Volume 16, Issue 6, December 2026.
Sub‐febrile endotoxemia, driven by low dose LPS, produces widespread multi‐system sex‐divergent outcomes, with males showing greater central inflammatory and behavioral vulnerability and females exhibiting distinct peripheral metabolic, thermoregulatory, and reproductive consequences.
Stina Börchers, Morgan Sotzen, Suyeun Byun, Doris Olekanma, Fuhua Hao, Andrew D. Patterson, Karolina P. Skibicka   +6 more
wiley   +1 more source

The Role of 5-HT1A and 5-HT7 Receptors in Anxiety-like Behavior in Mice Treated with Subchronic Atorvastatin. [PDF]

Curr Issues Mol Biol
Espinosa-Raya J, Trejo-Lazaro A, Briones-Aranda A, Romero-Nava R, Huang F, Cruz-Trujillo R, Espinosa-Juárez JV.   +6 more
europepmc   +1 more source

The Economic Crisis and Its Impact on Mental Health: A Scoping Review

Mental Health Science, Volume 4, Issue 4, December 2026.
ABSTRACT Economic crises characterized by financial instability, rising unemployment, and austerity measures are known to have profound social and public health consequences. While their economic impacts are widely studied, their effects on mental health across diverse populations and geographic regions remain fragmented and require synthesis.
Ioannis Adamopoulos, Aida Vafae Eslahi, Niki Syrou, Maad M. Mijwil, Pramila Thapa, Panagiotis Tsirkas, Antonios Bardavouras, Harshit Mishra, Konstantina Diamanti, Antonios Valamontes, John T. Karantonis, Mustafa Younis   +11 more
wiley   +1 more source

Association Between Cerebrospinal Fluid Ghrelin Levels and Depressive Symptoms is Moderated by Smoking: A Case‐Control Study

International Journal of Methods in Psychiatric Research, Volume 35, Issue 4, December 2026.
ABSTRACT Objective Smoking has been linked to both peripheral ghrelin levels and depressive symptoms. However, the association between cerebrospinal fluid (CSF) ghrelin levels and depressive symptoms, and the moderating role of smoking, remains unclear. This study aims to investigate the specific relationship among the three categories. Methods In this
Yueling Hu, Lingling Chen, Chunshui Yu, Yu‐Hsin Chen, Xingguang Luo, Yimin Kang, Li Chen, Yanlong Liu, Jue He, Fan Wang, Zengzeng Zhang   +10 more
wiley   +1 more source

Psychometric Properties of the Choosing Wisely Questions in a Large Psychiatric Sample

International Journal of Methods in Psychiatric Research, Volume 35, Issue 4, December 2026.
ABSTRACT Objectives The Choosing Wisely Questions (CWQ) support shared decision‐making and aim to reduce low‐value care, but their psychometric properties remain unclear. This study evaluated the structural validity, reliability, and item characteristics of the Swedish CWQ in a psychiatric sample.
Johan Bengtsson, Alma Andersson, Natalie Forss Lilja, Isabella Hultgren Farsani, Ellen Lissbrant, Björn Wettermark, Ida Blomqvist   +6 more
wiley   +1 more source