Results 21 to 30 of about 71,529 (343)

Investigation of Potential Antioxidant, Thrombolytic and Neuropharmacological Activities of Homalomena aromatica Leaves Using Experimental and In Silico Approaches

open access: yesMolecules, 2021
The leaves of Homalomena aromatica are traditionally used in Bangladesh for the treatment of different chronic ailments. The purpose of this study was to explore in vitro antioxidant, thrombolytic activities, and in vivo neuropharmacological effects of ...
Md. Sekendar Ali   +7 more
doaj   +1 more source

Dietary and botanical anxiolytics [PDF]

open access: yesMedical Science Monitor, 2012
Drugs used to treat anxiety have many negative side effects including addiction, depression, suicide, seizures, sexual dysfunction, headaches and more. Anxiolytic medications do not restore normal levels of neurotransmitters but instead manipulate the brain chemistry.
Mena S. Hanna   +5 more
openaire   +2 more sources

Effects of psychotropic agents on extinction of lever-press avoidance in a rat model of anxiety vulnerability

open access: yesFrontiers in Behavioral Neuroscience, 2014
Avoidance and its perseveration represent key features of anxiety disorders. Both pharmacological and behavioral approaches (i.e. anxiolytics and extinction therapy) have been utilized to modulate avoidance behavior in patients.
Xilu eJiao   +17 more
doaj   +1 more source

Citrus limon (L.) Burm f. Essential Oil Has Anxiolytic and Sedative Properties by Modulating GABAA-Receptors [PDF]

open access: yesBrazilian Archives of Biology and Technology, 2020
The high prevalence of anxiety disorders associated with pharmacotherapy side effects have motivated the search for new pharmacological agents. Species from Citrus genus, such as Citrus limon (sicilian lemon), have been used in folk medicine as a ...
Max Denisson Mauricio Viana   +7 more
doaj   +1 more source

Anxiolytic Effects of Repeated Cannabidiol Treatment in Teenagers With Social Anxiety Disorders

open access: yesFrontiers in Psychology, 2019
Accumulated evidence indicates that cannabidiol (CBD), a nonpsychotomimetic and nonaddictive main component of the Cannabis sativa plant, reverses anxiety-like behavior.
N. Masataka
semanticscholar   +1 more source

Structure-Dependent Activity of Natural GABA(A) Receptor Modulators

open access: yesMolecules, 2018
GABA(A) receptors are ligand-gated ion channels consisting of five subunits from eight subfamilies, each assembled in four hydrophobic transmembrane domains.
Serhat Sezai Çiçek
doaj   +1 more source

Anxiolytic-like effects of 4-phenyl-2-trichloromethyl-3H-1,5-benzodiazepine hydrogen sulfate in mice

open access: yesBrazilian Journal of Medical and Biological Research, 2000
The pharmacological effects of 4-phenyl-2-trichloromethyl-3H-1,5-benzodiazepine hydrogen sulfate (PTMB), a novel synthetic benzodiazepine, were examined in mice.
M.A. Rubin   +7 more
doaj   +1 more source

Patients’ desires for anxiolytic premedication – an observational study in adults undergoing elective surgery

open access: yesBMC Psychiatry, 2022
Background Most patients experiencing preoperative anxiety would welcome support in coping with their anxiety. Anxiolytic medication is a common way to address preoperative anxiety.
Frank Euteneuer   +4 more
doaj   +1 more source

Pharmacological validation of the anxiolytic, muscle relaxant and sedative like activities of Capsicum annuum in animal model

open access: yesBangladesh Journal of Pharmacology, 2017
The current study deals with anxiolytic, muscle relaxant and sedative like activities of Capsicum annuum in animal models. The crude extract was found safe in acute behavior and toxicity studies.
Muhammad Jawad   +6 more
doaj   +1 more source

Inverted U-Shaped Dose-Response Curve of the Anxiolytic Effect of Cannabidiol during Public Speaking in Real Life

open access: yesFrontiers in Pharmacology, 2017
The purpose of this study was to investigate whether the anxiolytic effect of cannabidiol (CBD) in humans follows the same pattern of an inverted U-shaped dose-effect curve observed in many animal studies.
A. Zuardi   +6 more
semanticscholar   +1 more source

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