Results 11 to 20 of about 47,485 (252)

Pharmacological effect of methanolic and hydro-alcoholic extract of Coconut endocarp

open access: yesJournal of Advanced Biotechnology and Experimental Therapeutics, 2020
Cocos nucifera used as natural remedies in a wide variety of diseases. The current experiment aimed to determine the qualitative phytochemicals, anxiolytic, anti-diarrheal, anti-inflammatory, thrombolytic and cytotoxic actions of C.
Saimun Akter   +9 more
doaj   +1 more source

Analgesic and Anxiolytic Effects of Gastrodin and Its Influences on Ferroptosis and Jejunal Microbiota in Complete Freund’s Adjuvant-Injected Mice

open access: yesFrontiers in Microbiology, 2022
This study investigated the effects of gastrodin (GAS) on analgesic, anxiolytic, ferroptosis, and jejunal microbiota in chronic inflammatory pain mice. The chronic inflammatory pain model of C57BL/6J mice was established by hindpaw injection of complete ...
Xin Chen   +6 more
doaj   +1 more source

Acute stress is detrimental to heart regeneration in zebrafish [PDF]

open access: yesOpen Biology, 2016
Psychological stress is one of the factors associated with human cardiovascular disease. Here, we demonstrate that acute perceived stress impairs the natural capacity of heart regeneration in zebrafish.
Pauline Sallin, Anna Jaźwińska
doaj   +1 more source

Structure-Dependent Activity of Natural GABA(A) Receptor Modulators

open access: yesMolecules, 2018
GABA(A) receptors are ligand-gated ion channels consisting of five subunits from eight subfamilies, each assembled in four hydrophobic transmembrane domains.
Serhat Sezai Çiçek
doaj   +1 more source

Latest updates on the serotonergic system in depression and anxiety

open access: yesFrontiers in Synaptic Neuroscience, 2023
Psychiatric disorders are among the leading causes of global health burden, with depression and anxiety being the most disabling subtypes. The two common disorders, depression and anxiety, usually coexist and are pathologically polygenic with complicated
Jianwen Lin   +11 more
doaj   +1 more source

Pharmacological validation of the anxiolytic, muscle relaxant and sedative like activities of Capsicum annuum in animal model

open access: yesBangladesh Journal of Pharmacology, 2017
The current study deals with anxiolytic, muscle relaxant and sedative like activities of Capsicum annuum in animal models. The crude extract was found safe in acute behavior and toxicity studies.
Muhammad Jawad   +6 more
doaj   +1 more source

Patients’ desires for anxiolytic premedication – an observational study in adults undergoing elective surgery

open access: yesBMC Psychiatry, 2022
Background Most patients experiencing preoperative anxiety would welcome support in coping with their anxiety. Anxiolytic medication is a common way to address preoperative anxiety.
Frank Euteneuer   +4 more
doaj   +1 more source

Anxiolytic-like effects of 4-phenyl-2-trichloromethyl-3H-1,5-benzodiazepine hydrogen sulfate in mice

open access: yesBrazilian Journal of Medical and Biological Research, 2000
The pharmacological effects of 4-phenyl-2-trichloromethyl-3H-1,5-benzodiazepine hydrogen sulfate (PTMB), a novel synthetic benzodiazepine, were examined in mice.
M.A. Rubin   +7 more
doaj   +1 more source

GABA and 5-HT Systems Are Involved in the Anxiolytic Effect of Gan-Mai-Da-Zao Decoction

open access: yesFrontiers in Neuroscience, 2019
The Gan-Mai-Da-Zao (GMDZ) decoction is one of the most famous Chinese medicine prescriptions to treat emotional diseases in China. Here we examined the anxiolytic-like effects of the GMDZ decoction in mice.
Hong-Shu Chen   +6 more
doaj   +1 more source

Dreams, Sleep, and Psychotropic Drugs

open access: yesFrontiers in Neurology, 2020
Over the past 60 years, the impact of psychotropic drugs on dream recall and content has been scarcely explored. A review of the few existing experimental results on the topic leads us to the following conclusions.
Alain Nicolas, Perrine M. Ruby
doaj   +1 more source

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