Results 31 to 40 of about 60,205 (323)

Driving performance and neurocognitive skills of long‐term users of benzodiazepine anxiolytics and hypnotics

Human psychopharmacology, 2019
The aim of this study is to compare actual driving performance and skills related to driving of patients using benzodiazepine anxiolytics or hypnotics for at least 6 months to that of healthy controls.
N. V. D. van der Sluiszen, A. Vermeeren, J. Verster, A. J. van de Loo, J. H. van Dijken, J. Veldstra, K. Brookhuis, D. de Waard, J. Ramaekers   +8 more
semanticscholar   +1 more source

Use of antidepressants and anxiolytics in early pregnancy and the risk of preeclampsia and gestational hypertension: a prospective study

BMC Pregnancy and Childbirth, 2019
BackgroundWe investigated the association between antidepressant and anxiolytic exposure during the first and early second trimester of pregnancy (
N. Bernard, J. Forest, George M. Tarabulsy, E. Bujold, D. Bouvier, Y. Giguère   +5 more
semanticscholar   +1 more source

Non-AIDS-related comorbidities in people living with HIV-1 aged 50 years and older: The AGING POSITIVE study. [PDF]

, 2018
OBJECTIVE: To characterize the profile of non-AIDS-related comorbidities (NARC) in the older HIV-1-infected population and to explore the factors associated with multiple NARC.
Abreu, R, Almeida, J, Castro, R, Coutinho, D, Lino, S, Lopes, MJ, Maltez, F, Mansinho, K, Miranda, AC, Neves, I, Pacheco, P, Piñero, C, Pássaro, L, Sarmento, E, Serrão, R, Tavares, AP, Velez, J   +16 more
core   +1 more source

Older adults and withdrawal from benzodiazepine hypnotics in general practice: effects on cognitive function, sleep, mood and quality of life [PDF]

, 2003
Background: Older adults are the main recipients of repeat prescriptions for benzodiazepine (BZD) hypnotics. BZDs can impair cognitive function and may not aid sleep when taken continuously for years.
Collins, R., Curran, H.V., Fletcher, S., Iliffe, S., Kee, S.C.Y., Woods, B.   +5 more
core   +1 more source

Anxiolytics targeting GABAA receptors: Insights on etifoxine

World Journal of Biological Psychiatry, 2018
Objectives: Anxiety and adjustment disorders are among the most prevalent mental health conditions. This review focuses on γ-aminobutyric acid receptor type A (GABAAR)-mediated anxiolysis, describing the action of both endogenous and exogenous modulators
P. Poisbeau, G. Gazzo, L. Calvel
semanticscholar   +1 more source

The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis

Brazilian Journal of Medical and Biological Research, 2001
This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether ...
R. Andreatini, C. Blanchard, R. Blanchard, M.L. Brandão, A.P. Carobrez, G. Griebel, F.S. Guimarães, S.L. Handley, F. Jenck, J.R. Leite, J. Rodgers, L.C. Schenberg, C. Da Cunha, F.G. Graeff   +13 more
doaj   +1 more source

Tualang Honey: A Decade of Neurological Research

Molecules, 2021
Tualang honey has been shown to protect against neurodegeneration, leading to improved memory/learning as well as mood. In addition, studies have also demonstrated its anti-inflammatory and antioxidant properties.
Khairunnuur Fairuz Azman, Che Badariah Abd Aziz, Rahimah Zakaria, Asma Hayati Ahmad, Nazlahshaniza Shafin, Che Aishah Nazariah Ismail   +5 more
doaj   +1 more source

Association between prescription of hypnotics/anxiolytics and mortality in multimorbid and non-multimorbid patients: a longitudinal cohort study in primary care

BMJ Open, 2019
Objectives To assess the risk of mortality in primary care patients, multimorbid (≥2 chronic conditions) or not, prescribed hypnotics/anxiolytics. Design A longitudinal cohort study Setting Primary healthcare in the Reykjavik area.
K. Linnet, J. Sigurdsson, M. O. Tomasdottir, E. Sigurdsson, L. Gudmundsson   +4 more
semanticscholar   +1 more source

Therapeutic effects of KRM-II-81, positive allosteric modulator for α2/3 subunit containing GABAA receptors, in a mouse model of Dravet syndrome

Frontiers in Pharmacology, 2023
Introduction: Dravet syndrome (DS) is an intractable epilepsy syndrome concomitant with neurodevelopmental disorder that begins in infancy. DS is dominantly caused by mutations in the SCN1A gene, which encodes the α subunit of a voltage-gated Na channel.
Sachiko Nakakubo, Yasuyoshi Hiramatsu, Takeru Goto, Syuhei Kimura, Masashi Narugami, Midori Nakajima, Yuki Ueda, Hideaki Shiraishi, Atsushi Manabe, Dishary Sharmin, James M. Cook, Kiyoshi Egawa   +11 more
doaj   +1 more source

The efficacy of benzodiazepines as acute anxiolytics in children: A meta‐analysis

Depression and Anxiety, 2017
Current practice guidelines do not recommend benzodiazepines for acute management of anxiety disorders in pediatric patients. However, in procedural settings, benzodiazepines are commonly used to relieve acute preprocedural stress.
Heide Kuang, Jessica A. Johnson, Jilian M. Mulqueen, M. Bloch   +3 more
semanticscholar   +1 more source