Results 71 to 80 of about 528,840 (339)

Massive B-Cell Infiltration and Organization Into Artery Tertiary Lymphoid Organs in the Aorta of Large Vessel Giant Cell Arteritis

Frontiers in Immunology, 2019
Giant cell arteritis (GCA) can be classified into Cranial(C)-GCA and Large Vessel(LV)-GCA. Based on analysis of temporal arteries, GCA is postulated to be T-cell-mediated.
Jacoba C. Graver, Annemieke M. H. Boots, Erlin A. Haacke, Erlin A. Haacke, Arjan Diepstra, Elisabeth Brouwer, Maria Sandovici   +6 more
doaj   +1 more source

Aortic Coarctation: Recent Developments in Experimental and Computational Methods to Assess Treatments for this Simple Condition [PDF]

, 2010
Coarctation of the aorta (CoA) is often considered a relatively simple disease, but long-term outcomes suggest otherwise as life expectancies are decades less than in the average population and substantial morbidity often exists.
Feinstein, Jeffrey A., LaDisa, John F., Taylor, Charles A.   +2 more
core   +2 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Mechanistic and pathological study of the genesis, growth, and rupture of abdominal aortic aneurysms [PDF]

, 2013
Postprint (published ...
Bordone, Maurizio, Loong, T. H., N.Y.Kwee, Eddy, Soudah Prieto, Eduardo, Sriram, N., Tan, C. H., Uei, P   +6 more
core   +3 more sources

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Role of the liver in splanchnic extraction of atrial natriuretic factor in the rat [PDF]

, 1992
Mesenteric, hepatic and splanchnic extraction of C-terminal and N-terminal atrial natriuretic factor was investigated in male Sprague-Dawley rats. Plasma concentrations (mean ± S.E.M.) of C-terminal atrial natriuretic factor were 55.0 ± 6.1 fmol/ml, 31.2
Alexander L. Gerbes, Arendt, Casado, Crozier, De Bold, Dieter Jüngst, Epstein, Gaétan Thibault, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gines, Gutkowska, Henriksen, Henriksen, Hollister, Inagami, Johnson, Krieter, Krieter, Kurusawa, Lang, Laragh, Manfred Bilzer, Masuda, Moreau, Nair, Needleman, Rochus Witthaut, Schütten, Sundsfjord, Tamburini, Thibault, Veit Gülberg, Veseley, Vierhapper, Vollmar, Widimsky   +39 more
core   +1 more source

Structural Motifs in Soft Fibrous Tissues: Revealing Structure‐Mechanics Relationships in Deformation and Tear Resistance for Biomimetic Material Design

Advanced Healthcare Materials, EarlyView.
This review explores how soft fibrous tissues achieve their remarkable mechanical behavior through recurring structural motifs across multiple length scales. It highlights key advances in mimicking these features using fiber‐reinforced hydrogels and hierarchical composites, offering insights into mechanical compatibility, flaw tolerance, and tear ...
Mirit Sharabi
wiley   +1 more source

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

Advanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren, Nurul Aisha Zainal Abidin, Allan Sun, Rui Gao, Yuxin Chen, Arian Nasser, Zihao Wang, Yunduo Charles Zhao, Alexander Dupuy, Anna Waterhouse, Qian Peter Su, Daniele Vigolo, Mike Chia Lun Wu, Lining Arnold Ju   +13 more
wiley   +1 more source

ANEURISM OF THE AORTA. [PDF]

The Lancet
n ...
openaire   +2 more sources

Targeting interleukin-1β protects from aortic aneurysms induced by disrupted transforming growth factor β signaling [PDF]

, 2017
Aortic aneurysms are life-threatening conditions with effective treatments mainly limited to emergency surgery or trans-arterial endovascular stent grafts, thus calling for the identification of specific molecular targets.
Bizzotto, Dario, Braghetta, Paola, Bressan, Giorgio M., Carnevale, Daniela, Carnevale, Lorenzo, Carnevale, Raimondo, Casaburo, Manuel, Cifelli, Giuseppe, DA ROS, Francesco, Fardella, Stefania, Iacobucci, Roberta, Lembo, Giuseppe, Perrotta, Marialuisa, Vinciguerra, Iolanda   +13 more
core   +1 more source