Results 141 to 150 of about 326,342 (329)

Surgical treatment of severe aortic valve stenosis with concomitant Fabry disease

open access: diamond, 2019
Athanasia Vlachou   +3 more
openalex   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

open access: yesAdvanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong   +22 more
wiley   +1 more source

Case report: Diagnosis of a double aortic arch in the primary care setting

open access: yesJournal of Family Medicine and Primary Care
A double aortic arch is a rare congenital heart anomaly not typically diagnosed in adults. It can present with nonspecific symptoms including dysphagia, a cough, and hoarseness which can lead to a delay in diagnosis or misdiagnosis.
Mary Chick
doaj   +1 more source

Histopathological Gap in Aortic Diseases: A Prospective Analysis. [PDF]

open access: yesInt J Mol Sci, 2023
Banceu CM   +7 more
europepmc   +1 more source

Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action

open access: yesAdvanced Science, EarlyView.
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang   +27 more
wiley   +1 more source

P5.09 AORTIC/PENILE INDEX IS A MARKER OF OCCULT CORONARY ARTERY DISEASE IN MIDDLE-AGED HYPERTENSIVE PATIENTS WITH ERECTILE DYSFUNCTION

open access: hybrid, 2011
N. Ioakeimidis   +9 more
openalex   +1 more source

Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

open access: yesAdvanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li   +9 more
wiley   +1 more source

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